fluorouracil has been researched along with Endometriosis in 12 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Endometriosis: A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis." | 7.76 | Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010) |
| "Although anastrozole, methotrexate, and progesterone were ineffective, 5-FU significantly decreased the proliferation of endometriotic cells in vitro and controlled the growth of both cells from ovarian endometrioma and deep infiltrating endometriosis." | 3.76 | Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo. ( Batteux, F; Chapron, C; Chéreau, C; Leconte, M; Ngô, C; Nicco, C; Weill, B, 2010) |
| " Treatment with oral contraceptive (OC) for endometriosis and later with cyclophosphamide, methotrexate, fluorouracil (CMF) for breast cancer produced a higher number of attacks." | 3.74 | Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura. ( Maggioni, F; Palmieri, A; Tropea, M; Zanchin, G, 2008) |
| "Endometriosis was not independently associated with the prognosis of the OCCC patients, even when the tumor was confined to stage I." | 1.43 | Prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma: Experiences at three academic institutions. ( Bai, H; Cao, D; Chen, J; Sha, G; Shen, K; Wang, Y; Yang, J; Yuan, F; Zhang, Z, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, H | 1 |
| Cao, D | 1 |
| Yuan, F | 1 |
| Sha, G | 1 |
| Yang, J | 1 |
| Chen, J | 1 |
| Wang, Y | 1 |
| Zhang, Z | 1 |
| Shen, K | 1 |
| Ngô, C | 1 |
| Nicco, C | 1 |
| Leconte, M | 1 |
| Chéreau, C | 1 |
| Weill, B | 1 |
| Batteux, F | 1 |
| Chapron, C | 1 |
| MOORE, JG | 1 |
| VANCAMPENHOUT, JL | 1 |
| BRANDKAMP, WW | 1 |
| Maggioni, F | 1 |
| Palmieri, A | 1 |
| Tropea, M | 1 |
| Zanchin, G | 1 |
| Scarabelli, C | 1 |
| Campagnutta, E | 1 |
| Yoshizawa, H | 1 |
| Kanazawa, K | 1 |
| Takeuchi, S | 1 |
| Okamura, Y | 1 |
| Goto, S | 1 |
| Kajiwara, T | 1 |
| Frank, S | 1 |
| Richter, K | 1 |
| Ehrhart, H | 1 |
| Penning, W | 1 |
| Meister, P | 1 |
| Schmidt, D | 1 |
| Götz, A | 1 |
| Bocklage, T | 1 |
| Lee, KR | 1 |
| Belinson, JL | 1 |
| Conte, PF | 1 |
| Sertoli, MR | 1 |
| Bruzzone, M | 1 |
| Rubagotti, A | 1 |
| Rosso, R | 1 |
| Bentivoglio, G | 1 |
| Conio, A | 1 |
| Pescetto, G | 1 |
| Schein, PS | 1 |
| Gear, EV | 1 |
| Speckhard, ME | 1 |
| Hurley, JD | 1 |
| Fetherston, WC | 1 |
| Grueninger, AJ | 1 |
2 reviews available for fluorouracil and Endometriosis
| Article | Year |
|---|---|
Chemotherapy in advanced ovarian cancer.
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Cystadenocarcinoma; Cystadeno | 1973 |
Dobbins WO 3d,+DOBBINS WO III: Rectal biopsy. A review of its diagnostic usefulness.
Topics: Amyloidosis; Biopsy; Colitis, Ulcerative; Crohn Disease; Cystic Fibrosis; Cysts; Deficiency Diseases | 1968 |
1 trial available for fluorouracil and Endometriosis
| Article | Year |
|---|---|
[Clinical trial of cisplatin in the treatment of ovarian carcinoma].
Topics: Adenocarcinoma; Adult; Aged; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Cystadenocarcino | 1982 |
9 other studies available for fluorouracil and Endometriosis
| Article | Year |
|---|---|
Prognostic value of endometriosis in patients with stage I ovarian clear cell carcinoma: Experiences at three academic institutions.
Topics: Adenocarcinoma, Clear Cell; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-125 Antigen; Ca | 2016 |
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation | 2010 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; C | 1964 |
Influence of physiologic hormonal modification and of hormonal treatment in a patient with a history of migraine with aura.
Topics: Amitriptyline; Analgesics; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Pro | 2008 |
Intraarterial infusion chemotherapy in the treatment of liver metastases from ovarian cancer.
Topics: Antineoplastic Agents; Cystadenocarcinoma; Doxorubicin; Drug Therapy, Combination; Endometriosis; Fe | 1981 |
[1st report on programmed chemotherapy of ovarian carcinoma].
Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinoma; Cystadenoma; Drug Thera | 1975 |
Uterine mullerian adenosarcoma following adenomyoma in a woman on tamoxifen therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltr | 1992 |
Cisplatin, methotrexate, and 5-fluorouracil combination chemotherapy for advanced ovarian cancer.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol | 1985 |
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide; | 1972 |