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fluorouracil and Encephalitis, Herpes Simplex

fluorouracil has been researched along with Encephalitis, Herpes Simplex in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Encephalitis, Herpes Simplex: An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

Research Excerpts

ExcerptRelevanceReference
"In advanced esophageal cancer patients, standard treatment involves chemoradiotherapy and surgery."1.43Herpes simplex virus-1 encephalitis induced by chemoradiotherapy and steroids in an esophageal cancer patient: a case report. ( Imoto, H; Kiyozaki, H; Obitsu, T; Rikiyama, T; Saito, M; Takata, O; Taniyama, Y, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saito, M1
Kiyozaki, H1
Obitsu, T1
Imoto, H1
Taniyama, Y1
Takata, O1
Rikiyama, T1
Cathomas, R1
Pelosi, E1
Smart, J1
Murray, N1
Simmonds, P1

Other Studies

2 other studies available for fluorouracil and Encephalitis, Herpes Simplex

ArticleYear
Herpes simplex virus-1 encephalitis induced by chemoradiotherapy and steroids in an esophageal cancer patient: a case report.
    BMC cancer, 2016, Mar-17, Volume: 16

    Topics: Acyclovir; Aged; Chemoradiotherapy; Cisplatin; Dexamethasone; Encephalitis, Herpes Simplex; Esophage

2016
Herpes simplex encephalitis as a complication of adjuvant chemotherapy treatment for breast cancer.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2005, Volume: 17, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosp

2005