fluorouracil has been researched along with Electrolytes in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Fluorouracil (5-FU) is a commonly used chemotherapy agent in clinical oncology practice." | 5.35 | Gastrointestinal microflora and mucins may play a critical role in the development of 5-Fluorouracil-induced gastrointestinal mucositis. ( Bowen, JM; Gibson, RJ; Hamilton, J; Keefe, DM; Logan, RM; Stringer, AM; Yeoh, AS, 2009) |
| "Here, we examined 95 patients with oesophageal cancer who received 5-fluorouracil and cisplatin (FP) to determine whether nephrotoxicity was affected by SLC22A2 808G>T polymorphism." | 1.39 | Absence of effect of SLC22A2 genotype on cisplatin-induced nephrotoxicity in oesophageal cancer patients receiving cisplatin and 5-fluorouracil: report of results discordant with those of earlier studies. ( Hinai, Y; Miura, M; Motoyama, S; Niioka, T, 2013) |
| "5-Fluorouracil (5-FU) is a commonly used chemotherapy agent in clinical oncology practice." | 1.35 | Gastrointestinal microflora and mucins may play a critical role in the development of 5-Fluorouracil-induced gastrointestinal mucositis. ( Bowen, JM; Gibson, RJ; Hamilton, J; Keefe, DM; Logan, RM; Stringer, AM; Yeoh, AS, 2009) |
| "Glucaric acid was also influenced by methotrexate and vincristine." | 1.28 | Biological monitoring screening of patients provided antineoplastic drugs including adriamycin, cyclophosphamide, 5-fluorouracil, methotrexate, and vincristine. ( Hee, SQ; Lowry, L; Newman, MA; Schoeny, R, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Byrne, JD | 1 |
| Jajja, MRN | 1 |
| O'Neill, AT | 1 |
| Schorzman, AN | 1 |
| Keeler, AW | 1 |
| Luft, JC | 1 |
| Zamboni, WC | 1 |
| DeSimone, JM | 1 |
| Yeh, JJ | 1 |
| Li, G | 1 |
| Meng, Y | 1 |
| Guo, L | 1 |
| Zhang, T | 1 |
| Liu, J | 1 |
| Hinai, Y | 1 |
| Motoyama, S | 1 |
| Niioka, T | 1 |
| Miura, M | 1 |
| Stringer, AM | 1 |
| Gibson, RJ | 1 |
| Logan, RM | 1 |
| Bowen, JM | 1 |
| Yeoh, AS | 1 |
| Hamilton, J | 1 |
| Keefe, DM | 1 |
| Newman, MA | 1 |
| Hee, SQ | 1 |
| Schoeny, R | 1 |
| Lowry, L | 1 |
5 other studies available for fluorouracil and Electrolytes
| Article | Year |
|---|---|
Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Drug Combinations; Dr | 2018 |
Formation of thermo-sensitive polyelectrolyte complex micelles from two biocompatible graft copolymers for drug delivery.
Topics: Antimetabolites, Antineoplastic; Biocompatible Materials; Drug Carriers; Electrolytes; Fluorouracil; | 2014 |
Absence of effect of SLC22A2 genotype on cisplatin-induced nephrotoxicity in oesophageal cancer patients receiving cisplatin and 5-fluorouracil: report of results discordant with those of earlier studies.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Agents; Blood Cell Count; Chemoradioth | 2013 |
Gastrointestinal microflora and mucins may play a critical role in the development of 5-Fluorouracil-induced gastrointestinal mucositis.
Topics: Animals; Antimetabolites, Antineoplastic; Bacteria; Colony Count, Microbial; Electrolytes; Female; F | 2009 |
Biological monitoring screening of patients provided antineoplastic drugs including adriamycin, cyclophosphamide, 5-fluorouracil, methotrexate, and vincristine.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Cyclopho | 1990 |