fluorouracil has been researched along with Eczema, Atopic in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An allergic contact dermatitis from fluorouracil developed in two patients 8 and 18 days respectively after institution of topical fluorouracil therapy." | 7.65 | Allergic contact dermatitis from topical fluorouracil. ( Goette, DK; Odom, RB; Owens, R, 1977) |
| "We designed a prospective and retrospective study to determine the incidence of allergic contact dermatitis to topical application of fluorouracil." | 7.65 | Allergic contact dermatitis to topical fluorouracil. ( Goette, DK; Odom, RB, 1977) |
| "An allergic contact dermatitis from fluorouracil developed in two patients 8 and 18 days respectively after institution of topical fluorouracil therapy." | 3.65 | Allergic contact dermatitis from topical fluorouracil. ( Goette, DK; Odom, RB; Owens, R, 1977) |
| "We designed a prospective and retrospective study to determine the incidence of allergic contact dermatitis to topical application of fluorouracil." | 3.65 | Allergic contact dermatitis to topical fluorouracil. ( Goette, DK; Odom, RB, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goette, DK | 3 |
| Odom, RB | 2 |
| Owens, R | 1 |
1 review available for fluorouracil and Eczema, Atopic
| Article | Year |
|---|---|
Topical chemotherapy with 5-fluorouracil. A review.
Topics: Administration, Topical; Chemical Phenomena; Chemistry; Dermatitis, Atopic; Dermatitis, Contact; Fem | 1981 |
2 other studies available for fluorouracil and Eczema, Atopic
| Article | Year |
|---|---|
Allergic contact dermatitis from topical fluorouracil.
Topics: Administration, Topical; Dermatitis, Atopic; Dermatitis, Contact; Female; Fluorouracil; Humans; Kera | 1977 |
Allergic contact dermatitis to topical fluorouracil.
Topics: California; Dermatitis, Atopic; Dermatitis, Contact; Fluorouracil; Keratosis; Prospective Studies; R | 1977 |