Page last updated: 2024-10-27

fluorouracil and Eardrum Perforation

fluorouracil has been researched along with Eardrum Perforation in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The mean patency of tympanic membrane perforations following incisional myringotomy was significantly longer in the 5-fluorouracil-treated group (11."3.73[The effect of topical application of 5-fluorouracil on patency times after incisional myringotomy of guinea pig tympanic membrane]. ( Ateş, G; Aydin, S; Bozkurt, Z; Eken, M; Evren, C; Sanli, A, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eken, M1
Evren, C1
Ateş, G1
Bozkurt, Z1
Sanli, A1
Aydin, S1

Other Studies

1 other study available for fluorouracil and Eardrum Perforation

ArticleYear
[The effect of topical application of 5-fluorouracil on patency times after incisional myringotomy of guinea pig tympanic membrane].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2006, Volume: 16, Issue:5

    Topics: Administration, Topical; Animals; Antimetabolites; Disease Models, Animal; Fluorouracil; Guinea Pigs

2006