fluorouracil has been researched along with Dystonia in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cranial dystonia is usually idiopathic but may be caused by trauma or medications." | 1.30 | Focal dystonia after chemotherapy: a case series. ( Brashear, A; Siemers, E, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ngeow, JY | 1 |
| Prakash, KM | 1 |
| Chowbay, B | 1 |
| Quek, ST | 1 |
| Choo, SP | 1 |
| Brashear, A | 1 |
| Siemers, E | 1 |
1 review available for fluorouracil and Dystonia
| Article | Year |
|---|---|
Capecitabine-induced oromandibular dystonia: a case report and literature review.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Asian People; Brain Stem; Capecitabine; Deoxycytidi | 2008 |
1 other study available for fluorouracil and Dystonia
| Article | Year |
|---|---|
Focal dystonia after chemotherapy: a case series.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Dyst | 1997 |