Page last updated: 2024-10-27

fluorouracil and Dystonia

fluorouracil has been researched along with Dystonia in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"Cranial dystonia is usually idiopathic but may be caused by trauma or medications."1.30Focal dystonia after chemotherapy: a case series. ( Brashear, A; Siemers, E, 1997)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ngeow, JY1
Prakash, KM1
Chowbay, B1
Quek, ST1
Choo, SP1
Brashear, A1
Siemers, E1

Reviews

1 review available for fluorouracil and Dystonia

ArticleYear
Capecitabine-induced oromandibular dystonia: a case report and literature review.
    Acta oncologica (Stockholm, Sweden), 2008, Volume: 47, Issue:6

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Asian People; Brain Stem; Capecitabine; Deoxycytidi

2008

Other Studies

1 other study available for fluorouracil and Dystonia

ArticleYear
Focal dystonia after chemotherapy: a case series.
    Journal of neuro-oncology, 1997, Volume: 34, Issue:2

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Dyst

1997