fluorouracil has been researched along with Dyspnea in 16 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Dyspnea: Difficult or labored breathing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pulmonary fibrosis is a rare complication of oxaliplatin and capecitabine/5-fluorouracil." | 4.87 | Pulmonary toxicity with oxaliplatin and capecitabine/5-Fluorouracil chemotherapy: a case report and review of the literature. ( Chan, AK; Choo, BA; Glaholm, J, 2011) |
| "The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin." | 1.33 | Is acute dyspnea related to oxaliplatin administration? ( Monfardini, S; Pasetto, LM, 2006) |
| "Hemoptysis was negligible until he died 8 months later." | 1.32 | [Clinical benefit of bronchial arterial infusion chemotherapy to pulmonary metastasis from colorectal cancer--report of two cases]. ( Ishigaki, T; Kitai, T; Kojima, N; Miki, A; Nishikawa, S; Nomura, A; Todo, G; Ukikusa, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chay, WY | 1 |
| Chew, L | 1 |
| Yeoh, TT | 1 |
| Tan, MH | 1 |
| Svensson, H | 1 |
| Einbeigi, Z | 1 |
| Johansson, H | 1 |
| Hatschek, T | 1 |
| Brandberg, Y | 1 |
| Shipman, KE | 1 |
| Arnold, I | 1 |
| Chan, AK | 1 |
| Choo, BA | 1 |
| Glaholm, J | 1 |
| Sargen, M | 1 |
| Wanat, KA | 1 |
| Jambusaria, A | 1 |
| Rosenbach, M | 1 |
| Sobanko, J | 1 |
| Miller, CJ | 1 |
| Lucchetta, M | 1 |
| Lonardi, S | 1 |
| Bergamo, F | 1 |
| Alberti, P | 1 |
| Velasco, R | 1 |
| Argyriou, AA | 1 |
| Briani, C | 1 |
| Bruna, J | 1 |
| Cazzaniga, M | 1 |
| Cortinovis, D | 1 |
| Cavaletti, G | 1 |
| Kalofonos, HP | 1 |
| Kitai, T | 1 |
| Nomura, A | 1 |
| Miki, A | 1 |
| Ukikusa, M | 1 |
| Kojima, N | 1 |
| Nishikawa, S | 1 |
| Ishigaki, T | 1 |
| Todo, G | 1 |
| Moreno-Vega, AL | 1 |
| Fuentes-Pradera, J | 1 |
| Gordón-Santiago, Mdel M | 1 |
| Vargas-Machuca, JC | 1 |
| Pasetto, LM | 1 |
| Monfardini, S | 1 |
| O'Shaughnessy, JA | 1 |
| Denicoff, AM | 1 |
| Venzon, DJ | 1 |
| Danforth, D | 1 |
| Pierce, LJ | 1 |
| Frame, JN | 1 |
| Bastian, A | 1 |
| Ghosh, B | 1 |
| Goldspiel, B | 1 |
| Miller, L | 1 |
| Wang, HM | 1 |
| Ng, SH | 1 |
| Wang, CH | 1 |
| Liaw, CT | 1 |
| Chen, JS | 1 |
| Yang, TS | 1 |
| Chen, IH | 1 |
| Meinardi, MT | 1 |
| Van Der Graaf, WT | 1 |
| Gietema, JA | 1 |
| Van Den Berg, MP | 1 |
| Sleijfer, DT | 1 |
| De Vries, EG | 1 |
| Haaksma, J | 1 |
| Boomsma, F | 1 |
| Van Veldhuisen, DJ | 1 |
| Lowenthal, RM | 1 |
| Jestrimski, KW | 1 |
| Shinde, SR | 1 |
| Shaha, PB | 1 |
| Shetty, PA | 1 |
| Shaw, HJ | 1 |
| Donegan, WL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment With the Combination of Epirubicin and Paclitaxel Alone or Together With Capecitabine as First Line Treatment in Metastatic Breast Cancer. A Multicenter, Randomized Phase III Study[NCT01433614] | Phase 3 | 304 participants (Actual) | Interventional | 2002-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluorouracil and Dyspnea
| Article | Year |
|---|---|
Pulmonary toxicity with oxaliplatin and capecitabine/5-Fluorouracil chemotherapy: a case report and review of the literature.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; Colectom | 2011 |
Systemic toxicity from occlusive therapy with topical 5-fluorouracil: a case report and review of the literature.
Topics: Abdominal Pain; Administration, Cutaneous; Antimetabolites, Antineoplastic; Chills; Diarrhea; Drug E | 2012 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast | 1986 |
3 trials available for fluorouracil and Dyspnea
| Article | Year |
|---|---|
Quality of life in women with metastatic breast cancer during 9 months after randomization in the TEX trial (epirubicin and paclitaxel w/o capecitabine).
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitab | 2010 |
A dose intensity study of FLAC (5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide) chemotherapy and Escherichia coli-derived granulocyte-macrophage colony-stimulating factor (GM-CSF) in advanced breast cancer patients.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dox | 1994 |
Intra-arterial plus i.v. chemotherapy for advanced bulky squamous cell carcinoma of the buccal mucosa.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 2001 |
10 other studies available for fluorouracil and Dyspnea
| Article | Year |
|---|---|
An association between transient hypokalemia and severe acute oxaliplatin-related toxicity predominantly in women.
Topics: Adult; Aged; Anaphylaxis; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deglutition | 2010 |
Case of epirubicin-induced cardiomyopathy in familial cardiomyopathy.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Ductal, Breast; Cardiac | 2011 |
Incidence of atypical acute nerve hyperexcitability symptoms in oxaliplatin-treated patients with colorectal cancer.
Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecita | 2012 |
[Clinical benefit of bronchial arterial infusion chemotherapy to pulmonary metastasis from colorectal cancer--report of two cases].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bronchial Arteries; Cisplatin; Colorectal Neoplasms; | 2003 |
Intraventricular metastases from rectal-sigmoid adenocarcinoma.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cardiac Tamponad | 2006 |
Is acute dyspnea related to oxaliplatin administration?
Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic | 2006 |
Evaluation of long term cardiotoxicity after epirubicin containing adjuvant chemotherapy and locoregional radiotherapy for breast cancer using various detection techniques.
Topics: Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms | 2002 |
Cardiac tamponade as the only initial feature of malignancy: a case report and review of the literature.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiac Tamponade; Common Col | 1986 |
Value of cytotoxic infusion in dyspnoea and dysphagia due to cancer.
Topics: Antineoplastic Agents; Cyclophosphamide; Deglutition Disorders; Dyspnea; Esophageal Neoplasms; Fluor | 1973 |
Cancer of the breast. Endocrine ablation, hormone therapy and chemotherapy.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Adult; Age Factors; Breast Neoplasms; Castration; Dyspnea; F | 1967 |