Page last updated: 2024-10-27

fluorouracil and Dyslipidemias

fluorouracil has been researched along with Dyslipidemias in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Dyslipidemias: Abnormalities in the serum levels of LIPIDS, including overproduction or deficiency. Abnormal serum lipid profiles may include high total CHOLESTEROL, high TRIGLYCERIDES, low HIGH DENSITY LIPOPROTEIN CHOLESTEROL, and elevated LOW DENSITY LIPOPROTEIN CHOLESTEROL.

Research Excerpts

ExcerptRelevanceReference
"Several reports have described hypertriglyceridemia (HTG) in cancer patients, including breast cancer patients treated with capecitabine (CAP)."7.79Hypertriglyceridemia in patients with metastatic breast cancer and treatment with capecitabine. ( Ariad, S; Geffen, DB; Geva, S; Lazarev, I, 2013)
"Several reports have described hypertriglyceridemia (HTG) in cancer patients, including breast cancer patients treated with capecitabine (CAP)."3.79Hypertriglyceridemia in patients with metastatic breast cancer and treatment with capecitabine. ( Ariad, S; Geffen, DB; Geva, S; Lazarev, I, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Geva, S1
Lazarev, I1
Geffen, DB1
Ariad, S1
Michie, CO1
Sakala, M1
Rivans, I1
Strachan, MW1
Clive, S1
Kanzaki, M1
Wada, J1
Nakatsuka, A1
Teshigawara, S1
Murakami, K1
Inoue, K1
Terami, T1
Katayama, A1
Nasu, J1
Yamamoto, K1
Makino, H1

Other Studies

3 other studies available for fluorouracil and Dyslipidemias

ArticleYear
Hypertriglyceridemia in patients with metastatic breast cancer and treatment with capecitabine.
    Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast

2013
The frequency and severity of capecitabine-induced hypertriglyceridaemia in routine clinical practice: a prospective study.
    British journal of cancer, 2010, Aug-24, Volume: 103, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Diabetes Mellitus; Dyslip

2010
A case of type 2 diabetes and metastatic liver cancer exhibiting hypercholesterolemia with abnormal lipoproteins.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure

2012