fluorouracil has been researched along with Dysgeusia in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Dysgeusia: A condition characterized by alterations of the sense of taste which may range from mild to severe, including gross distortions of taste quality.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The most common side effect of this medication is localized irritant dermatitis." | 1.37 | Metallic taste as a side effect of topical fluorouracil use. ( Han, SY; Youker, S, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basset-Seguin, N | 1 |
| Han, SY | 1 |
| Youker, S | 1 |
1 review available for fluorouracil and Dysgeusia
| Article | Year |
|---|---|
Topics: Alopecia; Anilides; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Basal Cel | 2018 |
1 other study available for fluorouracil and Dysgeusia
| Article | Year |
|---|---|
Metallic taste as a side effect of topical fluorouracil use.
Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Carcinoma in Situ; Carcinoma, Squamous C | 2011 |