fluorouracil has been researched along with Dysgerminoma in 17 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Dysgerminoma: A malignant ovarian neoplasm, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. It is the counterpart of the classical seminoma of the testis, to which it is both grossly and histologically identical. Dysgerminomas comprise 16% of all germ cell tumors but are rare before the age of 10, although nearly 50% occur before the age of 20. They are generally considered of low-grade malignancy but may spread if the tumor extends through its capsule and involves lymph nodes or blood vessels. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1646)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 57-year-old woman developed severe tumor lysis syndrome characterized by acute hyperuricemic nephropathy, hyperphosphatemia, hyperkalemia, and hypocalcemia after therapy with cyclophosphamide, methotrexate, and 5-fluorouracil for metastatic infiltrating ductal carcinoma of the breast involving the chest wall, lungs, pleurae, and liver." | 3.67 | Tumor lysis syndrome in nonhematopoietic neoplasms. ( Barton, JC, 1989) |
| " Both dosage and releasing time can be adjusted." | 1.27 | [Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites]. ( Himuro, H; Inoue, N; Kaetsu, I; Kitamura, K; Kubo, O; Sakairi, M; Tajika, T; Tajika, Y; Tohyama, T; Yoshida, M, 1986) |
| "Dysgerminomas are highly sensitive not only to irradiation but also to chemotherapy." | 1.27 | [Chemotherapy of dysgerminoma]. ( Brökelmann, J; Hartlapp, JH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, JP | 1 |
| Dockerty, MB | 1 |
| Symmonds, RE | 1 |
| Hayles, AB | 1 |
| Samuels, ML | 2 |
| Holoye, PY | 2 |
| Johnson, DE | 2 |
| Lanzotti, VJ | 1 |
| Boyle, LE | 1 |
| Smith, TL | 1 |
| Montague, DK | 1 |
| Ehrhart, H | 1 |
| Werquin, S | 1 |
| Kacet, S | 1 |
| Caron, J | 1 |
| Lacroix, D | 1 |
| Libersa, C | 1 |
| Coget, JM | 1 |
| Lekieffre, J | 1 |
| Barton, JC | 1 |
| Zilling, TL | 1 |
| Ahrén, B | 1 |
| Kubo, O | 1 |
| Himuro, H | 1 |
| Inoue, N | 1 |
| Tajika, Y | 1 |
| Tajika, T | 1 |
| Tohyama, T | 1 |
| Sakairi, M | 1 |
| Yoshida, M | 1 |
| Kaetsu, I | 1 |
| Kitamura, K | 1 |
| Brökelmann, J | 1 |
| Hartlapp, JH | 1 |
| Smith, JP | 1 |
| Rutledge, F | 1 |
| Sutow, WW | 1 |
| Kissel, P | 1 |
| Bessot, M | 1 |
| Duprez, A | 1 |
| Watt, J | 1 |
| Kühböck, J | 1 |
| Pokorny, D | 1 |
| Steinbach, K | 1 |
| Eggerth, G | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Ansfield, FJ | 1 |
| Mackman, S | 1 |
| Ramirez, G | 1 |
| Mil'man, MSh | 1 |
| Chirkina, IuM | 1 |
| Shek, BA | 1 |
| Li, MI | 1 |
| Chernyshev, VK | 1 |
3 reviews available for fluorouracil and Dysgerminoma
| Article | Year |
|---|---|
[Raynaud's phenomenon and finger necrosis after treatment of ovarian seminoma with bleomycin, vinblastine and 5-fluorouracil].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dysgerminoma; Female; Fingers; Flu | 1987 |
The use of cytotoxic drugs in the surgery of malignant disease.
Topics: Abdominal Neoplasms; Alkylating Agents; Animals; Antimetabolites; Antineoplastic Agents; Carcinoma, | 1968 |
Newer concepts in chemotherapy of cancer.
Topics: Breast Neoplasms; Colonic Neoplasms; Dysgerminoma; Female; Fluorouracil; Humans; Injections, Intra-A | 1972 |
14 other studies available for fluorouracil and Dysgerminoma
| Article | Year |
|---|---|
Ovarian and parovarian tumors in infants and children.
Topics: Adenocarcinoma; Adolescent; Child; Child, Preschool; Dysgerminoma; Female; Fluorouracil; Histocytoch | 1967 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fl | 1975 |
Combination chemotherapy in germinal cell tumors.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Choriocarcinoma; Cyclophosphamide; Drug Therapy | 1976 |
Retroperitoneal germ cell tumors with no apparent testicular involvement.
Topics: Adult; Biopsy; Cyclophosphamide; Dysgerminoma; Fluorouracil; Follow-Up Studies; Humans; Male; Methot | 1975 |
[Cell cycle and carcinochemotherapy: reality or hope? (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Drug Therapy, Combination; | 1975 |
Tumor lysis syndrome in nonhematopoietic neoplasms.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast Neoplasms; Carcinoma, Intraductal, | 1989 |
Ischaemic pancolitis: a serious complication of chemotherapy in a previously irradiated patient. Case report.
Topics: Carcinoma, Squamous Cell; Cisplatin; Colitis; Combined Modality Therapy; Dysgerminoma; Esophageal Ne | 1989 |
[Treatment of malignant brain tumors with slowly releasing anticancer drug-polymer composites].
Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Implants; Dysge | 1986 |
[Chemotherapy of dysgerminoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined | 1987 |
Malignant gynecologic tumors in children: current approaches to treatment.
Topics: Age Factors; Child; Child, Preschool; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; | 1973 |
[Loco-regional and sequential chemotherapy of advanced cancer].
Topics: Adult; Carcinoma; Carcinoma, Hepatocellular; Chemotherapy, Cancer, Regional Perfusion; Dysgerminoma; | 1968 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinom | 1968 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
[Antibodies to sarcolysine and 5-fluorouracil].
Topics: Animals; Antibody Formation; Basophils; Cross Reactions; Dysgerminoma; Erythrocytes; Esophageal Neop | 1974 |