fluorouracil has been researched along with Dysarthosis in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 65-year-old man started chemotherapy for metastatic pancreatic adenocarcinoma with oxaliplatin-irinotecan-leucovorin-5-fluorouracil (FOLFIRINOX)." | 3.80 | A curious case of oxaliplatin-induced neurotoxicity: recurrent, self-limiting dysarthria. ( Dasanu, CA; Joseph, R, 2014) |
| "5-fluorouracil was administered after the disappearance of dysarthria." | 2.47 | [A case of sigmoid colon cancer with temporary dysarthria associated with irinotecan]. ( Asaka, M; Fukushima, H; Iwanaga, I; Kawamoto, Y; Kobayashi, Y; Komatsu, Y; Nakatsumi, H; Sasaki, T; Sogabe, S; Takano, H; Uehata, Y; Yuki, S, 2011) |
| "The capecitabine treatment was terminated, and methylprednisolone treatment was administered and plasmapheresis procedure was carried out." | 1.91 | Capecitabine-related neurotoxicity presenting with agraphia. ( Bayram, E; Bicakci, S; Demir, T; Iscan, D; Tolay, R, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Iscan, D | 1 |
| Tolay, R | 1 |
| Bayram, E | 1 |
| Demir, T | 1 |
| Bicakci, S | 1 |
| Joseph, R | 1 |
| Dasanu, CA | 1 |
| Sogabe, S | 1 |
| Yuki, S | 1 |
| Takano, H | 1 |
| Kobayashi, Y | 1 |
| Nakatsumi, H | 1 |
| Sasaki, T | 1 |
| Kawamoto, Y | 1 |
| Fukushima, H | 1 |
| Iwanaga, I | 1 |
| Uehata, Y | 1 |
| Komatsu, Y | 1 |
| Asaka, M | 1 |
| De Marco, S | 1 |
| Squilloni, E | 1 |
| Vigna, L | 1 |
| Bertagnolio, MF | 1 |
| Sternberg, CN | 1 |
| Hamberg, P | 1 |
| De Jong, FA | 1 |
| Brandsma, D | 1 |
| Verweij, J | 1 |
| Sleijfer, S | 1 |
| Baz, DV | 1 |
| Bofill, JS | 1 |
| Nogueira, JA | 1 |
3 reviews available for fluorouracil and Dysarthosis
| Article | Year |
|---|---|
[A case of sigmoid colon cancer with temporary dysarthria associated with irinotecan].
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dys | 2011 |
Irinotecan-induced central nervous system toxicity. Report on two cases and review of the literature.
Topics: Adult; Antiemetics; Antineoplastic Agents, Phytogenic; Ataxia; Camptothecin; Capecitabine; Central N | 2008 |
Irinotecan-induced dysarthria.
Topics: Adenocarcinoma; Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Proto | 2001 |
3 other studies available for fluorouracil and Dysarthosis
| Article | Year |
|---|---|
Capecitabine-related neurotoxicity presenting with agraphia.
Topics: Adult; Agraphia; Capecitabine; Dysarthria; Fluorouracil; Humans; Leukoencephalopathies; Male | 2023 |
A curious case of oxaliplatin-induced neurotoxicity: recurrent, self-limiting dysarthria.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Administrat | 2014 |
Irinotecan chemotherapy associated with transient dysarthria and aphasia.
Topics: Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aphasia; Ca | 2004 |