fluorouracil has been researched along with Duodenitis in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Duodenitis: Inflammation of the DUODENUM section of the small intestine (INTESTINE, SMALL). Erosive duodenitis may cause bleeding in the UPPER GI TRACT and PEPTIC ULCER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One patient had severe ileitis caused by intravenous administration of 5-fluorouracil; the other had severe duodenitis caused by infusion of 5-floxuridine into the hepatic artery by an implanted pump." | 3.68 | Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings. ( Hiehle, JF; Levine, MS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chon, YE | 1 |
| Seong, J | 1 |
| Kim, BK | 1 |
| Cha, J | 1 |
| Kim, SU | 1 |
| Park, JY | 1 |
| Ahn, SH | 1 |
| Han, KH | 1 |
| Chon, CY | 1 |
| Shin, SK | 1 |
| Kim, DY | 1 |
| Hiehle, JF | 1 |
| Levine, MS | 1 |
2 other studies available for fluorouracil and Duodenitis
| Article | Year |
|---|---|
Gastroduodenal complications after concurrent chemoradiation therapy in patients with hepatocellular carcinoma: endoscopic findings and risk factors.
Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemoradiotherapy; Duodenal Ulcer | 2011 |
Gastrointestinal toxicity of 5-FU and 5-FUDR: radiographic findings.
Topics: Aged; Carcinoma; Duodenitis; Female; Floxuridine; Fluorouracil; Hepatic Artery; Humans; Ileitis; Inf | 1991 |