fluorouracil has been researched along with Duodenal Obstruction in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Duodenal Obstruction: Hindrance of the passage of luminal contents in the DUODENUM. Duodenal obstruction can be partial or complete, and caused by intrinsic or extrinsic factors. Simple obstruction is associated with diminished or stopped flow of luminal contents. Strangulating obstruction is associated with impaired blood flow to the duodenum in addition to obstructed flow of luminal contents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is important to understand that gastric cancer diagnosed poorly differentiated adenocarcinoma pathologically sometimes occurs duodenal invasion and obstructive jaundice." | 1.36 | [A case of duodenal invasion due to recurrent gastric cancer with obstructive jaundice treated by chemotherapy]. ( Fukuda, S; Hiraki, S; Kawaoka, T; Matsukuma, S; Nagashima, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Chen, K | 1 |
| Gong, J | 1 |
| Zheng, Y | 1 |
| Wang, T | 1 |
| Kawaoka, T | 1 |
| Matsukuma, S | 1 |
| Nagashima, A | 1 |
| Hiraki, S | 1 |
| Fukuda, S | 1 |
| Cha, BH | 1 |
| Lee, SH | 1 |
| Kim, JE | 1 |
| Yoo, JY | 1 |
| Park, YS | 1 |
| Kim, JW | 1 |
| Jeong, SH | 1 |
| Kim, N | 1 |
| Lee, DH | 1 |
| Hwang, JH | 1 |
3 other studies available for fluorouracil and Duodenal Obstruction
| Article | Year |
|---|---|
Combined arterial infusion and stent implantation compared with metal stent alone in treatment of malignant gastroduodenal obstruction.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Antineoplastic Combined Chemotherapy Protocols; Camptot | 2009 |
[A case of duodenal invasion due to recurrent gastric cancer with obstructive jaundice treated by chemotherapy].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phyto | 2010 |
Endoscopic self-expandable metallic stent placement in malignant pyloric or duodenal obstruction: does chemotherapy affect stent patency?
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cholangiopancreatography, Endoscopic Retrograd | 2013 |