fluorouracil has been researched along with Diabetic Feet in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of a single administration of small doses of 5-fluorouracil on results of skin plasty for syndrome of the diabetic foot were studied in 61 patients who had undergone local operations for pyo-necrotic diseases of the foot against the background of diabetes mellitus." | 5.12 | [Effects of short-term immunosuppression on the engraftment of skin transplants at syndrome of the diabetic foot]. ( Belov, VV; Bordunovskiĭ, VN; Grekova, NM; Lebedeva, IuV; Tertyshnik, SS, 2007) |
| "Although squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer, clinicians have difficulty diagnosing SCC of the toe because its clinical features can mimic other less serious diseases." | 1.43 | A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema. ( Kim, HW; Kim, JE; Ko, JY; Kwon, HI; Park, HC; Ro, YS, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, HC | 1 |
| Kwon, HI | 1 |
| Kim, HW | 1 |
| Kim, JE | 1 |
| Ro, YS | 1 |
| Ko, JY | 1 |
| Grekova, NM | 2 |
| Lebedeva, IuV | 2 |
| Bordunovskiĭ, VN | 2 |
| Belov, VV | 1 |
| Tertyshnik, SS | 1 |
| Sakai, H | 1 |
| Fukami, Y | 1 |
| Ibe, M | 1 |
| Tamura, T | 1 |
| Hashimoto, Y | 1 |
| Iizuka, H | 1 |
1 trial available for fluorouracil and Diabetic Feet
| Article | Year |
|---|---|
[Effects of short-term immunosuppression on the engraftment of skin transplants at syndrome of the diabetic foot].
Topics: Biopsy; Blood Transfusion, Autologous; Diabetic Foot; Female; Fluorouracil; Follow-Up Studies; Graft | 2007 |
3 other studies available for fluorouracil and Diabetic Feet
| Article | Year |
|---|---|
A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; | 2016 |
[Method for improving results of local operations for pyo-necrotic disease of the foot associated with diabetes mellitus].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Diabetic Foot; Fluoroura | 2003 |
A verrucous lesion on skin grafted after necrotizing fasciitis in a diabetic patient successfully treated with combined topical 5-FU and tacalcitol.
Topics: Administration, Topical; Diabetic Foot; Dihydroxycholecalciferols; Drug Therapy, Combination; Fascii | 1997 |