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fluorouracil and Developmental Coordination Disorder

fluorouracil has been researched along with Developmental Coordination Disorder in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Kuilenburg, AB1
Dobritzsch, D1
Meinsma, R1
Haasjes, J1
Waterham, HR1
Nowaczyk, MJ1
Maropoulos, GD1
Hein, G1
Kalhoff, H1
Kirk, JM1
Baaske, H1
Aukett, A1
Duley, JA1
Ward, KP1
Lindqvist, Y1
van Gennip, AH1

Other Studies

1 other study available for fluorouracil and Developmental Coordination Disorder

ArticleYear
Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure.
    The Biochemical journal, 2002, May-15, Volume: 364, Issue:Pt 1

    Topics: Age of Onset; Amino Acids; Animals; Cells, Cultured; Child, Preschool; Crystallography, X-Ray; Dihyd

2002