fluorouracil has been researched along with Dermatitis Exfoliativa in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The management of patients with advanced colorectal cancer remains dependent on the optimal use of 5-Fluorouracil (5-FU)." | 9.07 | Protracted venous infusion 5-fluorouracil and interferon-alpha in advanced and refractory colorectal cancer. ( Carter, R; Cunningham, D; Evans, C; Findlay, M; Ford, H; Hill, A; Husband, J; Nicolson, M; Norman, A, 1994) |
| "The management of patients with advanced colorectal cancer remains dependent on the optimal use of 5-Fluorouracil (5-FU)." | 5.07 | Protracted venous infusion 5-fluorouracil and interferon-alpha in advanced and refractory colorectal cancer. ( Carter, R; Cunningham, D; Evans, C; Findlay, M; Ford, H; Hill, A; Husband, J; Nicolson, M; Norman, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsuda, K | 1 |
| Namiki, T | 1 |
| Ueno, M | 1 |
| Hashimoto, T | 1 |
| Hanafusa, T | 1 |
| Yokozeki, H | 1 |
| SULLIVAN, RD | 1 |
| ZUREK, WZ | 1 |
| Findlay, M | 1 |
| Hill, A | 1 |
| Cunningham, D | 1 |
| Norman, A | 1 |
| Nicolson, M | 1 |
| Ford, H | 1 |
| Husband, J | 1 |
| Evans, C | 1 |
| Carter, R | 1 |
| Vukelja, SJ | 1 |
| Lombardo, FA | 1 |
| James, WD | 1 |
| Weiss, RB | 1 |
| Atkins, JN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicentre Randomized Phase II Study of Neoadjuvant Trastuzumab Plus Docetaxel With and Without Bevacizumab and Trastuzumab Plus Docetaxel Plus Non-pegylated Liposome-encapsulated Doxorubicin (NPLD) With and Without Bevacizumab in HER2-positive Early Bre[NCT01367028] | Phase 2 | 100 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluorouracil and Dermatitis Exfoliativa
| Article | Year |
|---|---|
Protracted venous infusion 5-fluorouracil and interferon-alpha in advanced and refractory colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms | 1994 |
4 other studies available for fluorouracil and Dermatitis Exfoliativa
| Article | Year |
|---|---|
Tegafur/gimeracil/oteracil (TS-1)-induced erythroderma with an extensive mucosal involvement and hand-foot syndrome.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neop | 2017 |
PROTRACTED AMBULATORY INFUSION CANCER CHEMOTHERAPY BY THE WATKINS CHRONOMETRIC INFUSOR.
Topics: Adenoma; Antineoplastic Agents; Breast Neoplasms; Carcinosarcoma; Colonic Neoplasms; Dermatitis, Exf | 1964 |
Pyridoxine for the palmar-plantar erythrodysesthesia syndrome.
Topics: Dermatitis, Exfoliative; Fluorouracil; Hand Dermatoses; Humans; Male; Middle Aged; Nervous System Di | 1989 |
Fluorouracil and the palmar-plantar erythrodysesthesia syndrome.
Topics: Dermatitis, Exfoliative; Female; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Middle Aged | 1985 |