fluorouracil has been researched along with Deafness, Transitory in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 18 patients, 14 with colorectal cancer and 4 with pancreatic cancer, were included in this study." | 2.79 | Oxaliplatin and ototoxicity: is it really safe for hearing? ( Babacan, NA; Doğan, M; Kaçan, T; Kiliçkap, S; Koç, S; Seker, MM; Uysal, IO; Yüce, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yüce, S | 1 |
| Seker, MM | 1 |
| Koç, S | 1 |
| Uysal, IO | 1 |
| Kaçan, T | 1 |
| Doğan, M | 2 |
| Babacan, NA | 1 |
| Kiliçkap, S | 1 |
| Schifter, M | 1 |
| Barrett, AP | 1 |
1 trial available for fluorouracil and Deafness, Transitory
| Article | Year |
|---|---|
Oxaliplatin and ototoxicity: is it really safe for hearing?
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Co | 2014 |
1 other study available for fluorouracil and Deafness, Transitory
| Article | Year |
|---|---|
Multiple cranial nerve involvement leading to diagnosis of nasopharyngeal carcinoma: case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cranial Nerves; Deglutition Disorders; Fl | 1992 |