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fluorouracil and Cytomegalovirus Retinitis

fluorouracil has been researched along with Cytomegalovirus Retinitis in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Cytomegalovirus Retinitis: Infection of the retina by cytomegalovirus characterized by retinal necrosis, hemorrhage, vessel sheathing, and retinal edema. Cytomegalovirus retinitis is a major opportunistic infection in AIDS patients and can cause blindness.

Research Excerpts

ExcerptRelevanceReference
" Cyclosporine A devices were prepared for the treatment of uveitis."4.79Review: implants. ( Ashton, P; Blandford, DL; Jaffe, GJ; Martin, DF; Nussenblatt, RB; Pearson, PA, 1994)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashton, P1
Blandford, DL1
Pearson, PA1
Jaffe, GJ1
Martin, DF1
Nussenblatt, RB1

Reviews

1 review available for fluorouracil and Cytomegalovirus Retinitis

ArticleYear
Review: implants.
    Journal of ocular pharmacology, 1994,Winter, Volume: 10, Issue:4

    Topics: Animals; Cyclosporine; Cytomegalovirus Retinitis; Delayed-Action Preparations; Drug Implants; Filter

1994