fluorouracil has been researched along with Cystic Echinococcosis in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since 5-FU treatments did not cause toxic effect in mice, further in vivo studies will be performed by adjusting the dosage and the frequency of treatments." | 5.46 | Experimental cystic echinococcosis therapy: In vitro and in vivo combined 5-fluorouracil/albendazole treatment. ( Benoit, JP; Elissondo, MC; Elissondo, N; Gambino, G; Gamboa, GU; Pensel, PE, 2017) |
| "Human cystic echinococcosis is a zoonosis caused by the metacestode stage of the tapeworm Echinococcus granulosus." | 1.40 | In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells. ( Albani, C; Benoit, JP; Elissondo, MC; Gamboa, GU; Pensel, PE, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, P | 1 |
| Li, J | 1 |
| Mao, R | 1 |
| Qi, H | 1 |
| Yang, L | 1 |
| Zhou, Q | 1 |
| Tian, M | 1 |
| Zhang, W | 1 |
| Bao, Y | 1 |
| Pensel, PE | 2 |
| Elissondo, N | 1 |
| Gambino, G | 1 |
| Gamboa, GU | 2 |
| Benoit, JP | 2 |
| Elissondo, MC | 2 |
| Albani, C | 1 |
| Coltorti, EA | 1 |
| Varela-Diaz, VM | 1 |
4 other studies available for fluorouracil and Cystic Echinococcosis
| Article | Year |
|---|---|
In vitro Scolicidal Efficacy of 5-Fluorouracil and Radiation Against Protoscoleces of Echinococcus granulosus Sensu Lato.
Topics: Animals; Echinococcosis; Echinococcus granulosus; Fluorouracil; Real-Time Polymerase Chain Reaction; | 2022 |
Experimental cystic echinococcosis therapy: In vitro and in vivo combined 5-fluorouracil/albendazole treatment.
Topics: Albendazole; Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echinococcosis; E | 2017 |
In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells.
Topics: Animals; Anticestodal Agents; Dose-Response Relationship, Drug; Echinococcosis; Echinococcus granulo | 2014 |
Survival and viability criteria of hydatid cysts maintained in vitro.
Topics: Animals; Azides; Culture Media; Echinococcosis; Echinococcus; Fluorouracil; Freezing; Gerbillinae; M | 1975 |