Page last updated: 2024-10-27

fluorouracil and Cystadenocarcinoma

fluorouracil has been researched along with Cystadenocarcinoma in 28 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Cystadenocarcinoma: A malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix."7.68Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990)
"Intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil has been used to rescue patients from peritoneal carcinomatosis after perforated cystadenocarcinoma of the large bowel or appendix."3.68Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix. ( Jaffe, G; Landy, D; Pascal, R; Sugarbaker, PH, 1990)
" Except for melatonin, all neuroendocrine hormones used in this study inhibited proliferation of KF cells derived from human serous cystadenocarcinoma of the ovary in a dose-dependent manner."3.67Inhibition of human ovarian cancer cell proliferation in vitro by neuroendocrine hormones. ( Iwano, I; Kato, K; Kikuchi, Y; Kita, T; Miyauchi, M, 1989)
" Other adverse sequelae, such as abdominal pain, were manageable with medication."1.28Adverse effects of intraperitoneal fluorouracil in patients with optimal residual ovarian cancer after second-look laparotomy: a Gynecologic Oncology Group Study. ( Blessing, JA; Homesley, HD; Walton, LA, 1989)
"A case of brain metastasis in ovarian cancer is reported."1.27[Metastatic brain tumor after chemotherapy of ovarian cancer]. ( Chen, JT; Fujimoto, I; Fukuda, K; Hasumi, K; Masubuchi, K; Sakamoto, A; Yamauchi, K, 1987)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199021 (75.00)18.7374
1990's6 (21.43)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iyama, S1
Takahashi, Y1
Shintani, N1
Fujikawa, K1
Ohkubo, S1
Sato, Y2
Sato, T1
Ohnuma, K1
Niitsu, Y1
Scarabelli, C1
Campagnutta, E1
Benedetti Panici, P1
Di Roberto, P1
Margariti, PA1
Villani, L1
Sacco, F1
Cognetti, F1
Bompiani, A1
Hashimi, LA1
Khalyl, MF1
Salem, PA1
Yoshizawa, H1
Kanazawa, K1
Takeuchi, S1
Okamura, Y1
Goto, S1
Kajiwara, T1
Nuutinen, LS1
Kauppila, A1
Ryhänen, P1
Niinimäki, A1
Kivinen, S1
Saarela, M1
Pakarinen, A1
Hollmén, A1
Rózewicki, S1
Rzepka, I1
Górski, H1
Ogorodnikova, IS1
Zubkova, TV1
Gaĭrabed'iants, NG1
Frank, S1
Richter, K1
Ehrhart, H1
Penning, W1
Meister, P1
Schmidt, D1
Götz, A1
Wu, JZ1
Dempke, WC1
Hosking, LK1
Hill, BT1
Gebbia, V1
Russo, A1
Gebbia, N1
Rausa, L1
Ingria, F1
Spatafora, G1
Zerillo, G1
Cimino, A1
Pastorello, T1
Ferrara, P1
Novikova, EG1
Borisov, VI1
Dmitriev, DG1
Zel'vin, BM1
Karseladze, AI1
Shchitkov, KG1
Li, AD1
Sugarbaker, PH1
Landy, D1
Jaffe, G1
Pascal, R1
Wood, D1
Silberman, AW1
Heifetz, L1
Memsic, L1
Shabot, MM1
Tanaka, Y1
Ueda, G1
Tanizawa, O1
Miyake, H1
Kohno, M1
Nishiyama, S1
Inoue, H1
Ikeuchi, H1
Sekigawa, S1
Matsunaga, S1
Kikuchi, Y1
Kita, T1
Miyauchi, M1
Iwano, I1
Kato, K1
Walton, LA1
Blessing, JA1
Homesley, HD1
Barlow, JJ1
Lele, SB1
Emrich, LJ1
Fukuda, K1
Chen, JT1
Fujimoto, I1
Yamauchi, K1
Hasumi, K1
Masubuchi, K1
Sakamoto, A1
Theissig, P1
Theissig, F1
Lotze, W1
Paule, B1
Frydman, R1
Chasseray, JM1
Schein, PS1
Smith, JP3
Rutledge, F2
Speckhard, ME1
Hurley, JD1
Fetherston, WC1
Grueninger, AJ1
Wharton, JT1
Rutledge, FN1
Baer, JW1

Reviews

2 reviews available for fluorouracil and Cystadenocarcinoma

ArticleYear
[A case of recurrent biliary cystadenocarcinoma successfully treated with 5FU/CDDP systemic chemotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2006, Volume: 103, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Cystadenocarcino

2006
Chemotherapy in advanced ovarian cancer.
    Geriatrics, 1973, Volume: 28, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Cystadenocarcinoma; Cystadeno

1973

Trials

3 trials available for fluorouracil and Cystadenocarcinoma

ArticleYear
[Clinical trial of cisplatin in the treatment of ovarian carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Cystadenocarcino

1982
Intensified nutrition as an adjunct to cytotoxic chemotherapy in gynaecological cancer patients.
    Clinical oncology, 1982, Volume: 8, Issue:2

    Topics: Antineoplastic Agents; Body Weight; Cisplatin; Cyclophosphamide; Cystadenocarcinoma; Doxorubicin; Dr

1982
Long-term survival rates with various chemotherapeutic regimens in stages III and IV ovarian adenocarcinoma. The influence of optimum pretreatment surgical resection.
    American journal of obstetrics and gynecology, 1985, Jun-01, Volume: 152, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Antineoplastic Combined Chemotherapy Protocol

1985

Other Studies

23 other studies available for fluorouracil and Cystadenocarcinoma

ArticleYear
Intraarterial infusion chemotherapy in the treatment of liver metastases from ovarian cancer.
    European journal of gynaecological oncology, 1981, Volume: 2, Issue:3

    Topics: Antineoplastic Agents; Cystadenocarcinoma; Doxorubicin; Drug Therapy, Combination; Endometriosis; Fe

1981
The treatment of 48 patients affected by ovarian carcinoma at stages III and IV F.I.G.O.
    European journal of gynaecological oncology, 1981, Volume: 2, Issue:3

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Cyclophosphamide; Cystadenocarcinoma; Female; Fluorouracil; H

1981
Supraventricular tachycardia. A probable complication of platinum treatment.
    Oncology, 1984, Volume: 41, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cystadenocarcinoma; Dox

1984
[Early results of polychemotherapy in advanced ovarian tumors].
    Ginekologia polska, 1979, Volume: 50, Issue:11

    Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Adult; Aged; Carcinoma, Papillary; Cyclophosphamide; Cyst

1979
[Ultrastructural changes in ovarian tumor cancer cells under the influence of preoperative chemotherapy].
    Arkhiv patologii, 1976, Volume: 38, Issue:2

    Topics: Cell Nucleolus; Chromatin; Cystadenocarcinoma; Female; Fluorouracil; Humans; Mitochondria; Ovarian N

1976
[1st report on programmed chemotherapy of ovarian carcinoma].
    Fortschritte der Medizin, 1975, Oct-09, Volume: 93, Issue:28

    Topics: Adenocarcinoma; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinoma; Cystadenoma; Drug Thera

1975
[Chemosensitivity testing of adenocystic tongue and gingival cancer cell lines].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 1992, Volume: 27, Issue:2

    Topics: Antineoplastic Agents; Cystadenocarcinoma; Doxorubicin; Drug Screening Assays, Antitumor; Fluorourac

1992
Expression of collateral sensitivity to cisplatin, methotrexate, and fluorouracil in a human ovarian carcinoma cell line following exposure to fractionated x-irradiation in vitro.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3

    Topics: Cisplatin; Combined Modality Therapy; Cystadenocarcinoma; Drug Resistance; Female; Fluorouracil; Glu

1992
High-dose folinic acid and 5-fluorouracil plus cisplatin on a weekly schedule in the treatment of advanced cancer of the head and neck.
    Journal of cancer research and clinical oncology, 1992, Volume: 118, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squamous Cell;

1992
[Polymer-drug complexes in the treatment of extensive ovarian cancer].
    Sovetskaia meditsina, 1991, Issue:11

    Topics: Adult; Cellulose; Cyclophosphamide; Cystadenocarcinoma; Doxorubicin; Evaluation Studies as Topic; Fe

1991
Histologic changes induced by intraperitoneal chemotherapy with 5-fluorouracil and mitomycin C in patients with peritoneal carcinomatosis from cystadenocarcinoma of the colon or appendix.
    Cancer, 1990, Apr-01, Volume: 65, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Colonic Neoplasm

1990
Cystadenocarcinoma of the pancreas: neo-adjuvant therapy and CEA monitoring.
    Journal of surgical oncology, 1990, Volume: 43, Issue:1

    Topics: Carcinoembryonic Antigen; Combined Modality Therapy; Cystadenocarcinoma; Fluorouracil; Humans; Male;

1990
[A case of amylase-producing ovarian tumor].
    Gan no rinsho. Japan journal of cancer clinics, 1986, Volume: 32, Issue:1

    Topics: Amylases; Antineoplastic Combined Chemotherapy Protocols; Cystadenocarcinoma; Cytarabine; Female; Fl

1986
Inhibition of human ovarian cancer cell proliferation in vitro by neuroendocrine hormones.
    Gynecologic oncology, 1989, Volume: 32, Issue:1

    Topics: beta-Endorphin; Cell Division; Cystadenocarcinoma; DNA, Neoplasm; Dose-Response Relationship, Drug;

1989
Adverse effects of intraperitoneal fluorouracil in patients with optimal residual ovarian cancer after second-look laparotomy: a Gynecologic Oncology Group Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling;

1989
[Metastatic brain tumor after chemotherapy of ovarian cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1987, Volume: 33, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cisplatin; Cyclop

1987
[Rare late metastasis of a successfully treated advanced ovarian cancer].
    Zentralblatt fur Gynakologie, 1986, Volume: 108, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cyclopho

1986
Multimodal approach to the treatment of stage III ovarian carcinoma: preliminary report of a pilot study and critical review.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1985, Volume: 39, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; C

1985
Chemotherapy in the treatment of cancer of the ovary.
    American journal of obstetrics and gynecology, 1970, Jul-01, Volume: 107, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Female

1970
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
    Oncology, 1972, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide;

1972
Chemotherapy of ovarian cancer. New approaches to treatment.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Antineoplastic Agents; Cyclophosphamide; Cystadenocarcinom

1972
Metastatic ovarian cancer.
    Clinical obstetrics and gynecology, 1973, Volume: 16, Issue:2

    Topics: Adenocarcinoma, Mucinous; Cyclophosphamide; Cystadenocarcinoma; Dactinomycin; Drug Combinations; Fem

1973
An unusual case of adenocarcinoma of the pancreas.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:7

    Topics: Adenocarcinoma, Mucinous; Adult; Antibiotics, Antineoplastic; Aorta, Abdominal; Calcinosis; Cystaden

1974