fluorouracil has been researched along with Cutaneous T-Cell Lymphoma in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 83-year-old Caucasian man with cutaneous T-cell lymphoma developed an aggressive squamous cell carcinoma of the left forearm, which recurred and metastasized after Mohs micrographic surgery and systemic chemotherapy with cis-platin and 5-fluorouracil." | 3.70 | Invasive squamous cell carcinoma with sporotrichoid metastasis in a patient with cutaneous T cell lymphoma treated with chronic extracorporeal photopheresis. ( Beer, R; Elizeri, Y; Gmyrek, R; Grossman, ME; Oster, MW; Schneiderman, P; Silvers, DN, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lindberg, MR | 1 |
| DiLorenzo, A | 1 |
| DeSimone, JA | 1 |
| Kannangara, AP | 1 |
| Levitan, D | 1 |
| Fleischer, AB | 1 |
| Gmyrek, R | 1 |
| Beer, R | 1 |
| Elizeri, Y | 1 |
| Oster, MW | 1 |
| Silvers, DN | 1 |
| Schneiderman, P | 1 |
| Grossman, ME | 1 |
3 other studies available for fluorouracil and Cutaneous T-Cell Lymphoma
| Article | Year |
|---|---|
Cutaneous T-Cell Lymphoma Treatment: Case Series of Combination Therapy With Intralesional Injections of 5-Fluorouracil and Topical Imiquimod.
Topics: Fluorouracil; Humans; Imiquimod; Injections, Intralesional; Lymphoma, T-Cell, Cutaneous; Skin Neopla | 2023 |
Six patients with early-stage cutaneous T-cell lymphoma successfully treated with topical 5-fluorouracil.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Female; | 2010 |
Invasive squamous cell carcinoma with sporotrichoid metastasis in a patient with cutaneous T cell lymphoma treated with chronic extracorporeal photopheresis.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Carci | 1999 |