fluorouracil has been researched along with Cushing's Syndrome in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome." | 1.25 | The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| AbdelBaki, MS | 1 |
| Waguespack, SG | 1 |
| Salceda, V | 1 |
| Jones, J | 1 |
| Stapleton, SL | 1 |
| Baskin, DS | 1 |
| Okcu, MF | 1 |
| Rajeev, SP | 1 |
| McDougall, S | 1 |
| Terlizzo, M | 1 |
| Palmer, D | 1 |
| Daousi, C | 1 |
| Cuthbertson, DJ | 1 |
| Britton, S | 1 |
| Thorén, M | 1 |
| Sjoberg, HE | 1 |
| Wilson, CB | 1 |
| Winternitz, WW | 1 |
| Rush, BF | 1 |
| Walton, KN | 1 |
| Maddy, JA | 1 |
1 review available for fluorouracil and Cushing's Syndrome
| Article | Year |
|---|---|
Significant response of pituitary carcinoma to carboplatin, leucovorin and fluorouracil chemotherapy: a pediatric case report and review of the literature.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc | 2017 |
3 other studies available for fluorouracil and Cushing's Syndrome
| Article | Year |
|---|---|
Evolution in functionality of a metastatic pancreatic neuroendocrine tumour (pNET) causing Cushing's syndrome: treatment response with chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cushing Syndrome; Doxorubicin; Fluorouracil; | 2014 |
The immunological hazard of Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum | 1975 |
Cryohypophysectomy: indications, technic, and results.
Topics: Acromegaly; Adenoma, Chromophobe; Adult; Breast Neoplasms; Carcinoma; Castration; Cryosurgery; Cushi | 1967 |