Page last updated: 2024-10-27

fluorouracil and Cushing's Syndrome

fluorouracil has been researched along with Cushing's Syndrome in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome."1.25The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AbdelBaki, MS1
Waguespack, SG1
Salceda, V1
Jones, J1
Stapleton, SL1
Baskin, DS1
Okcu, MF1
Rajeev, SP1
McDougall, S1
Terlizzo, M1
Palmer, D1
Daousi, C1
Cuthbertson, DJ1
Britton, S1
Thorén, M1
Sjoberg, HE1
Wilson, CB1
Winternitz, WW1
Rush, BF1
Walton, KN1
Maddy, JA1

Reviews

1 review available for fluorouracil and Cushing's Syndrome

ArticleYear
Significant response of pituitary carcinoma to carboplatin, leucovorin and fluorouracil chemotherapy: a pediatric case report and review of the literature.
    Journal of neuro-oncology, 2017, Volume: 135, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carc

2017

Other Studies

3 other studies available for fluorouracil and Cushing's Syndrome

ArticleYear
Evolution in functionality of a metastatic pancreatic neuroendocrine tumour (pNET) causing Cushing's syndrome: treatment response with chemotherapy.
    BMC endocrine disorders, 2014, Aug-24, Volume: 14

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cushing Syndrome; Doxorubicin; Fluorouracil;

2014
The immunological hazard of Cushing's syndrome.
    British medical journal, 1975, Dec-20, Volume: 4, Issue:5998

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum

1975
Cryohypophysectomy: indications, technic, and results.
    International surgery, 1967, Volume: 48, Issue:1

    Topics: Acromegaly; Adenoma, Chromophobe; Adult; Breast Neoplasms; Carcinoma; Castration; Cryosurgery; Cushi

1967