Page last updated: 2024-10-27

fluorouracil and Cranial Nerve Diseases

fluorouracil has been researched along with Cranial Nerve Diseases in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Cranial Nerve Diseases: Disorders of one or more of the twelve cranial nerves. With the exception of the optic and olfactory nerves, this includes disorders of the brain stem nuclei from which the cranial nerves originate or terminate.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, Y1
Sun, Y1
Liang, SB1
Zong, JF1
Li, WF1
Chen, M1
Chen, L1
Mao, YP1
Tang, LL1
Guo, Y1
Lin, AH1
Liu, MZ1
Ma, J1
Du, CR1
Ying, HM1
Kong, FF1
Zhai, RP1
Hu, CS1

Reviews

1 review available for fluorouracil and Cranial Nerve Diseases

ArticleYear
Concurrent chemoradiotherapy was associated with a higher severe late toxicity rate in nasopharyngeal carcinoma patients compared with radiotherapy alone: a meta-analysis based on randomized controlled trials.
    Radiation oncology (London, England), 2015, Mar-26, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Cisplatin; Confidence

2015

Trials

1 trial available for fluorouracil and Cranial Nerve Diseases

ArticleYear
Progress report of a randomized trial comparing long-term survival and late toxicity of concurrent chemoradiotherapy with adjuvant chemotherapy versus radiotherapy alone in patients with stage III to IVB nasopharyngeal carcinoma from endemic regions of Ch
    Cancer, 2013, Jun-15, Volume: 119, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Chemother

2013