fluorouracil has been researched along with Corneal Opacity in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Corneal Opacity: Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 2-month-old female infant with intractable congenital glaucoma and diffuse corneal opacification underwent trabeculectomy with 5-fluorouracil (5-FU) injection in both eyes followed by penetrating keratoplasty (PKP) combined with partial cyclocryotherapy in the right eye." | 3.69 | Ultrasonographic findings of the optic disc in congenital glaucoma. ( Barash, D; Kremer, I; Lusky, M; Snir, M; Yassur, Y, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, TI | 1 |
| Lee, SY | 1 |
| Pak, JH | 1 |
| Tchah, H | 1 |
| Kook, MS | 1 |
| Hurvitz, LM | 1 |
| Bergman, RH | 1 |
| Spigelman, AV | 1 |
| Snir, M | 1 |
| Kremer, I | 1 |
| Barash, D | 1 |
| Lusky, M | 1 |
| Yassur, Y | 1 |
4 other studies available for fluorouracil and Corneal Opacity
| Article | Year |
|---|---|
Mitomycin C, ceramide, and 5-fluorouracil inhibit corneal haze and apoptosis after PRK.
Topics: Animals; Apoptosis; Ceramides; Cornea; Corneal Opacity; Fluorouracil; Lasers, Excimer; Mitomycin; Ph | 2006 |
Corneal opacification after 5-fluorouracil injections.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Corneal Opacity; Female; Fluorouracil; Glaucoma, Open- | 1994 |
The role of fibroblast inhibitors on corneal healing following photorefractive keratectomy with 193-nanometer excimer laser in rabbits.
Topics: Animals; Cornea; Corneal Opacity; Corneal Stroma; Fibroblasts; Fluorouracil; Heparin; Laser Therapy; | 1994 |
Ultrasonographic findings of the optic disc in congenital glaucoma.
Topics: Antimetabolites; Corneal Opacity; Cryotherapy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Hu | 1996 |