Page last updated: 2024-10-27

fluorouracil and Corneal Diseases

fluorouracil has been researched along with Corneal Diseases in 52 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Corneal Diseases: Diseases of the cornea.

Research Excerpts

ExcerptRelevanceReference
"In this prospective study, 76 patients with primary pterygium (76 eyes) were categorized into two groups: the control group with 31 patients who did not receive cyclosporine treatment, and the cyclosporine group with 45 patients who received topical cyclosporine A (0."9.30Topical cyclosporine A 0.05% before and after surgery to prevent pterygium recurrence. ( Meneghim, RLFS; Natsuaki, KL; Oliveira, AC; Padovani, CR; Satto, LH; Schellini, SA; Viveiros, MMH, 2019)
"In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery."9.07Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992)
"A 26-year-old, wild caught, male Malayan tapir at the Miami Metrozoo with bilateral corneal papillomas was serially immobilized and given subconjunctival injections of fluorouracil."7.71Fluorouracil as a treatment for corneal papilloma in a Malayan tapir. ( Karpinski, LG; Miller, CL, 2002)
"Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53."7.685-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991)
"The antimetabolite 5-fluorouracil (5-FU) has been used to inhibit fibroblastic growth to increase the success rate in glaucoma filtration surgery."7.67Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery. ( Hersh, P; Kersten, D; Lee, DA; Melamed, S, 1987)
"We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications."7.67Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil. ( Driebe, WT; Heuer, DK; Knapp, A; Stern, GA, 1987)
"In this prospective study, 76 patients with primary pterygium (76 eyes) were categorized into two groups: the control group with 31 patients who did not receive cyclosporine treatment, and the cyclosporine group with 45 patients who received topical cyclosporine A (0."5.30Topical cyclosporine A 0.05% before and after surgery to prevent pterygium recurrence. ( Meneghim, RLFS; Natsuaki, KL; Oliveira, AC; Padovani, CR; Satto, LH; Schellini, SA; Viveiros, MMH, 2019)
"In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery."5.07Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992)
"A 26-year-old, wild caught, male Malayan tapir at the Miami Metrozoo with bilateral corneal papillomas was serially immobilized and given subconjunctival injections of fluorouracil."3.71Fluorouracil as a treatment for corneal papilloma in a Malayan tapir. ( Karpinski, LG; Miller, CL, 2002)
"To investigate the incidence of complications reportedly caused by the use of 5-fluorouracil (5-FU) in glaucoma filtering surgery, we performed trabeculectomy with 5-FU on 57 eyes of 56 patients with advanced glaucoma."3.68Incidence of complications following 5-fluorouracil with trabeculectomies. ( Gieser, SC; Jacob, A; Raju, R; Sen, S; Thomas, R, 1993)
"Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53."3.685-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991)
"The antimetabolite 5-fluorouracil (5-FU) has been used to inhibit fibroblastic growth to increase the success rate in glaucoma filtration surgery."3.67Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery. ( Hersh, P; Kersten, D; Lee, DA; Melamed, S, 1987)
"We studied four patients who, having received postoperative 5-fluorouracil after glaucoma filtering operations, developed serious corneal complications."3.67Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil. ( Driebe, WT; Heuer, DK; Knapp, A; Stern, GA, 1987)
"Mitomycin C has been shown in studies to be highly effective but has short-term and long-term side-effects that may be intolerable."2.49Topical chemotherapy for ocular surface squamous neoplasia. ( Karp, CL; Nanji, AA; Sayyad, FE, 2013)
" Based on the Wuerzburg bleb classification score (WBCS) for postoperative wound healing evaluation, 30 of these operations of group A (group B: n = 26) did not receive 5 FU postoperatively (controls), 67 (93) received up to 7 postoperative injections of 5 mg 5 FU (normal dosage group), and 72 (93) received more than 7 injections (high dosage group)."1.36[Corneal epitheliopathy following trabeculectomy with postoperative adjunctive 5-fluorouracil]. ( Geerling, G; Grehn, F; Klink, T; Reiter, C; Schultheiss, A; Wimmer, S, 2010)
"Capecitabine (CPC) was administered as an oral immunosuppressive agent."1.34Histopathologic evidence of capecitabine corneal toxicity in dogs. ( Bentley, E; Dubielzig, R; McAnulty, J; Milovancev, M; Schmiedt, C; Zarfoss, M, 2007)
"To evaluate the efficacy of pulse dosing of topical 5-fluorouracil (5-FU) in the treatment of conjunctival and corneal intraepithelial neoplasia."1.315-Fluorouracil for the treatment of intraepithelial neoplasia of the conjunctiva and cornea. ( Curry, CD; Engelbrecht, NE; Ford, JG; Walter, KA; Yeatts, RP, 2000)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.69)18.7374
1990's16 (30.77)18.2507
2000's13 (25.00)29.6817
2010's15 (28.85)24.3611
2020's4 (7.69)2.80

Authors

AuthorsStudies
Godin, F1
Mercado, C3
Larco, P1
Pacheco L, MA1
Borroni, D1
Chacon Aponte, A1
Agarwal, A1
Kaliki, S1
Murthy, SI1
Le, VNH1
Wabnig, F1
Bachmann, B1
Cursiefen, C1
Aboumourad, RJ1
Galor, A5
Karp, CL7
Chaugule, SS1
Park, J1
Finger, PT1
Polski, A1
Sibug Saber, M1
Kim, JW1
Berry, JL1
Venkateswaran, N1
Koenig, SB1
Koenig, LR1
Connor, TB1
Simons, KB1
Meneghim, RLFS1
Satto, LH1
Natsuaki, KL1
Oliveira, AC1
Padovani, CR1
Viveiros, MMH1
Schellini, SA1
Nanji, AA1
Sayyad, FE1
Wong, RK1
Greene, DP1
Shield, DR1
Eberhart, CG1
Huang, JJ1
Shayegani, A1
Overton, TL1
Allbaugh, RA1
Whitley, D1
Ben-Shlomo, G1
Griggs, A1
Tofflemire, KL1
Whitley, EM1
Joag, MG1
Sise, A1
Murillo, JC1
Sayed-Ahmed, IO1
Wong, JR1
Parrozzani, R1
Frizziero, L1
Trainiti, S1
Testi, I1
Miglionico, G1
Pilotto, E1
Blandamura, S1
Fassina, A1
Midena, E1
Ashkenazy, N1
Wang, G1
Acosta, CM1
Lenhart, PD1
Randleman, JB1
Grossniklaus, HE1
Stulting, RD1
Hau, S1
Barton, K1
Reiter, C1
Wimmer, S1
Schultheiss, A1
Klink, T1
Grehn, F1
Geerling, G1
Shousha, MA1
Perez, VL1
Hoffmann, R1
Ventura, R1
Chang, V1
Dubovy, SR2
Wang, J1
Oellers, P1
Kao, AA1
Abdelaziz, A1
Feuer, W1
Hirji, N1
Griffiths, M1
Karpinski, LG1
Miller, CL1
Schechter, BA2
Nagler, RS2
Stone, DU1
Butt, AL1
Chodosh, J1
Tomlins, PJ1
Savant, V1
Quinlan, M1
Zarfoss, M1
Bentley, E1
Milovancev, M1
Schmiedt, C1
Dubielzig, R1
McAnulty, J1
Slezak, H1
Thomas, R1
Jacob, A1
Raju, R1
Gieser, SC1
Sen, S1
Hayashi, M1
Ibaraki, N1
Tsuru, T1
Baldassare, RD1
Brunette, I1
Desjardins, DC1
Amyot, M1
Yeatts, RP2
Ford, JG2
Stanton, CA1
Reed, JW1
Fechtner, RD1
Manche, EE1
Afshari, MA1
Singh, K1
Rothman, RF1
Liebmann, JM1
Ritch, R1
Pires, RT1
Chokshi, A1
Tseng, SC1
Waikhom, B1
Fraunfelder, FT1
Henner, WD1
Walkhom, B1
Engelbrecht, NE1
Curry, CD1
Walter, KA1
Doe, EA1
Budenz, DL1
Gedde, SJ1
Imami, NR1
Lai, MM1
Haller, JA1
Skuta, GL3
Beeson, CC1
Higginbotham, EJ1
Lichter, PR1
Musch, DC1
Bergstrom, TJ1
Klein, TB1
Falck, FY1
Phelan, MJ2
Franks, WA1
Hitchings, RA1
Loane, ME2
Weinreb, RN2
Wright, MM1
Grajewski, AL1
Cristol, SM1
Parrish, RK1
Lemp, MA1
Peterson, MR1
Stanley, SA1
Stank, TM1
Krupin, T1
Feitl, ME1
de Keizer, RJ1
de Wolff-Rouendaal, D1
van Delft, JL1
Lee, DA1
Hersh, P1
Kersten, D1
Melamed, S1
Knapp, A1
Heuer, DK1
Stern, GA1
Driebe, WT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489]Phase 470 participants Interventional2004-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fluorouracil and Corneal Diseases

ArticleYear
Topical chemotherapy for ocular surface squamous neoplasia.
    Current opinion in ophthalmology, 2013, Volume: 24, Issue:4

    Topics: Administration, Topical; Antimetabolites, Antineoplastic; Carcinoma in Situ; Conjunctival Neoplasms;

2013
Corneal complications of glaucoma surgery.
    Current opinion in ophthalmology, 2009, Volume: 20, Issue:2

    Topics: Corneal Diseases; Corneal Transplantation; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Graft

2009

Trials

2 trials available for fluorouracil and Corneal Diseases

ArticleYear
Topical cyclosporine A 0.05% before and after surgery to prevent pterygium recurrence.
    Arquivos brasileiros de oftalmologia, 2019, 06-27, Volume: 82, Issue:5

    Topics: Adult; Combined Modality Therapy; Conjunctiva; Corneal Diseases; Cyclosporine; Female; Fluorouracil;

2019
Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery.
    Ophthalmology, 1992, Volume: 99, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Corneal Diseases; Epithelium; Female; Fluorouracil; Glaucoma; Humans

1992

Other Studies

48 other studies available for fluorouracil and Corneal Diseases

ArticleYear
Epithelial downgrowth leading to graft rejection after penetrating keratoplasty.
    European journal of ophthalmology, 2023, Volume: 33, Issue:4

    Topics: Cornea; Corneal Diseases; Fluorouracil; Graft Rejection; Humans; Infant; Keratoplasty, Penetrating;

2023
Corneal squamous neoplasia: masquerades and management outcomes at a rural eyecare centre.
    BMJ case reports, 2023, May-02, Volume: 16, Issue:5

    Topics: Carcinoma, Squamous Cell; Conjunctival Neoplasms; Corneal Diseases; Eye Neoplasms; Fluorouracil; Hum

2023
Epithelial downgrowth after Descemet membrane endothelial keratoplasty.
    European journal of ophthalmology, 2021, Volume: 31, Issue:2

    Topics: Aged; Antimetabolites; Corneal Diseases; Descemet Stripping Endothelial Keratoplasty; Endothelium, C

2021
Case Series: High-resolution Optical Coherence Tomography as an Optical Biopsy in Ocular Surface Squamous Neoplasia.
    Optometry and vision science : official publication of the American Academy of Optometry, 2021, 05-01, Volume: 98, Issue:5

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biopsy; C

2021
Topical chemotherapy for giant ocular surface squamous neoplasia of the conjunctiva and cornea: Is surgery necessary?
    Indian journal of ophthalmology, 2018, Volume: 66, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma,

2018
Extending far and wide: the role of biopsy and staging in the management of ocular surface squamous neoplasia.
    Clinical & experimental ophthalmology, 2019, Volume: 47, Issue:2

    Topics: Aged; Antineoplastic Agents; Biopsy; Carcinoma, Squamous Cell; Conjunctival Neoplasms; Corneal Disea

2019
Comparison of Topical 5-Fluorouracil and Interferon Alfa-2b as Primary Treatment Modalities for Ocular Surface Squamous Neoplasia.
    American journal of ophthalmology, 2019, Volume: 199

    Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic

2019
Successful management of epithelial ingrowth after sequential intracameral 5-fluorouracil and Descemet-stripping automated endothelial keratoplasty.
    Journal of cataract and refractive surgery, 2019, Volume: 45, Issue:5

    Topics: Aged; Anterior Chamber; Antimetabolites; Combined Modality Therapy; Cornea; Corneal Diseases; Descem

2019
5-Fluorouracil for epithelial downgrowth after Descemet stripping automated endothelial keratoplasty.
    Cornea, 2013, Volume: 32, Issue:12

    Topics: Aged; Antimetabolites; Corneal Diseases; Descemet Stripping Endothelial Keratoplasty; Female; Fluoro

2013
A pulse-dose topical 1% 5-fluorouracil treatment regimen in a young dog with corneal squamous cell carcinoma.
    Veterinary ophthalmology, 2015, Volume: 18, Issue:4

    Topics: Administration, Ophthalmic; Animals; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Corn

2015
Topical 5-Fluorouracil 1% as Primary Treatment for Ocular Surface Squamous Neoplasia.
    Ophthalmology, 2016, Volume: 123, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Conjuncti

2016
Topical 1% 5-fluoruracil as a sole treatment of corneoconjunctival ocular surface squamous neoplasia: long-term study.
    The British journal of ophthalmology, 2017, Volume: 101, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamo

2017
Immunosuppression as a Possible Risk Factor for Interferon Nonresponse in Ocular Surface Squamous Neoplasia.
    Cornea, 2017, Volume: 36, Issue:4

    Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Conjunctiv

2017
Confocal microscopic diagnosis of epithelial downgrowth.
    Cornea, 2008, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Aged; Cell Nucleus; Corneal Diseases; Epithelium, Corneal; Eye Injuries, Penetrat

2008
[Corneal epitheliopathy following trabeculectomy with postoperative adjunctive 5-fluorouracil].
    Klinische Monatsblatter fur Augenheilkunde, 2010, Volume: 227, Issue:11

    Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy; Corne

2010
Diagnosis and management of conjunctival and corneal intraepithelial neoplasia using ultra high-resolution optical coherence tomography.
    Ophthalmology, 2011, Volume: 118, Issue:8

    Topics: Administration, Topical; Aged; Aged, 80 and over; Biopsy; Carcinoma in Situ; Conjunctival Neoplasms;

2011
Predictors of ocular surface squamous neoplasia recurrence after excisional surgery.
    Ophthalmology, 2012, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma in Situ; Carcinoma, Squamous Cell; Conjunctival Neoplasms;

2012
Snailtrack corneal changes following subconjunctival injection of 5-fluorouracil.
    Eye (London, England), 2012, Volume: 26, Issue:11

    Topics: Antimetabolites; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Glaucoma; Humans

2012
Fluorouracil as a treatment for corneal papilloma in a Malayan tapir.
    Veterinary ophthalmology, 2002, Volume: 5, Issue:3

    Topics: Animals; Animals, Zoo; Antimetabolites, Antineoplastic; Conjunctiva; Corneal Diseases; Diagnosis, Di

2002
Successful treatment with 5-Fu.
    Ophthalmology, 2003, Volume: 110, Issue:4

    Topics: Administration, Topical; Aged; Antineoplastic Agents; Carcinoma in Situ; Conjunctival Neoplasms; Cor

2003
Successful treatment with 5-Fu.
    Ophthalmology, 2003, Volume: 110, Issue:6

    Topics: Administration, Topical; Aged; Antineoplastic Agents; Carcinoma in Situ; Conjunctival Neoplasms; Cor

2003
Ocular surface squamous neoplasia: a standard of care survey.
    Cornea, 2005, Volume: 24, Issue:3

    Topics: Administration, Topical; Antineoplastic Agents; Biopsy; Combined Modality Therapy; Conjunctival Neop

2005
Failure of intracameral fluorouracil to resolve an epithelial ingrowth following clear corneal cataract surgery.
    Journal of cataract and refractive surgery, 2007, Volume: 33, Issue:5

    Topics: Antimetabolites; Cataract Extraction; Corneal Diseases; Epithelium, Corneal; Fluorouracil; Glaucoma,

2007
Histopathologic evidence of capecitabine corneal toxicity in dogs.
    Veterinary pathology, 2007, Volume: 44, Issue:5

    Topics: Animals; Capecitabine; Cornea; Corneal Diseases; Deoxycytidine; Dog Diseases; Dogs; Female; Fluorour

2007
[Drug-induced eye lesions in the aged].
    Aktuelle Gerontologie, 1983, Volume: 13, Issue:5

    Topics: Aged; Antipsychotic Agents; Aspirin; Cataract; Conjunctival Diseases; Corneal Diseases; Eye Diseases

1983
Incidence of complications following 5-fluorouracil with trabeculectomies.
    Indian journal of ophthalmology, 1993, Volume: 41, Issue:4

    Topics: Combined Modality Therapy; Corneal Diseases; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inci

1993
Lamellar keratoplasty after trabeculectomy with 5-fluorouracil.
    American journal of ophthalmology, 1994, Feb-15, Volume: 117, Issue:2

    Topics: Corneal Diseases; Corneal Transplantation; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Middl

1994
Corneal ectasia secondary to excessive ocular massage following trabeculectomy with 5-fluorouracil.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1996, Volume: 31, Issue:5

    Topics: Adult; Antimetabolites; Corneal Diseases; Dilatation, Pathologic; Fluorouracil; Glaucoma; Humans; Ma

1996
Topical 5-fluorouracil in treating epithelial neoplasia of the conjunctiva and cornea.
    Ophthalmology, 1995, Volume: 102, Issue:9

    Topics: Administration, Topical; Adult; Aged; Antimetabolites, Antineoplastic; Biopsy; Carcinoma in Situ; Ch

1995
Management of coexisting pseudophakic bullous keratopathy and open-angle glaucoma.
    Journal of glaucoma, 1998, Volume: 7, Issue:1

    Topics: Administration, Topical; Aged; Cataract Extraction; Corneal Diseases; Female; Fluorouracil; Follow-U

1998
Delayed corneal epitheliopathy after antimetabolite-augmented trabeculectomy.
    Journal of glaucoma, 1998, Volume: 7, Issue:4

    Topics: Aged; Antimetabolites; Cornea; Corneal Diseases; Epithelium; Female; Fluorouracil; Humans; Mitomycin

1998
Noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil.
    American journal of ophthalmology, 1999, Volume: 128, Issue:2

    Topics: Aged; Antimetabolites; Conjunctiva; Cornea; Corneal Diseases; Diagnosis, Differential; Exfoliation S

1999
Amniotic membrane transplantation or conjunctival limbal autograft for limbal stem cell deficiency induced by 5-fluorouracil in glaucoma surgeries.
    Cornea, 2000, Volume: 19, Issue:3

    Topics: Aged; Amnion; Cell Transplantation; Conjunctiva; Corneal Diseases; Epithelial Cells; Epithelium, Cor

2000
Severe ocular irritation and corneal deposits associated with capecitabine use.
    The New England journal of medicine, 2000, Sep-07, Volume: 343, Issue:10

    Topics: Antineoplastic Agents; Breast Neoplasms; Capecitabine; Corneal Diseases; Deoxycytidine; Female; Fluo

2000
5-Fluorouracil for the treatment of intraepithelial neoplasia of the conjunctiva and cornea.
    Ophthalmology, 2000, Volume: 107, Issue:12

    Topics: Administration, Topical; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma in Situ

2000
Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.
    Ophthalmology, 2001, Volume: 108, Issue:10

    Topics: Adult; Antihypertensive Agents; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follow-Up Stud

2001
Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil.
    American journal of ophthalmology, 2002, Volume: 133, Issue:4

    Topics: Adult; Anterior Chamber; Antimetabolites; Corneal Diseases; Epithelial Cells; Eye Injuries; Fluorour

2002
Reversible corneal keratinization following trabeculectomy and treatment with 5-fluorouracil.
    Ophthalmic surgery, 1990, Volume: 21, Issue:4

    Topics: Aged; Conjunctiva; Corneal Diseases; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pressur

1990
Complications of 5--fluorouracil after trabeculectomy.
    Eye (London, England), 1991, Volume: 5 ( Pt 4)

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conjunctiva; Conjunctival Diseases; Corneal Diseases; Fe

1991
Reducing corneal toxicity of 5-fluorouracil in the early postoperative period following glaucoma filtering surgery.
    Australian and New Zealand journal of ophthalmology, 1991, Volume: 19, Issue:3

    Topics: Aged; Aged, 80 and over; Aphakia; Corneal Diseases; Female; Fluorouracil; Glaucoma, Open-Angle; Huma

1991
5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome.
    Ophthalmology, 1991, Volume: 98, Issue:3

    Topics: Adult; Cataract Extraction; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follo

1991
Striate melanokeratosis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1991, Volume: 109, Issue:7

    Topics: Corneal Diseases; Fluorouracil; Humans; Keratosis; Melanosis

1991
Striate melanokeratosis following trabeculectomy with 5-fluorouracil.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:9

    Topics: Corneal Diseases; Fluorouracil; Glaucoma, Open-Angle; Humans; Keratosis; Male; Melanosis; Middle Age

1990
Glaucoma secondary to epithelial downgrowth and 5-fluorouracil.
    Ophthalmic surgery, 1990, Volume: 21, Issue:10

    Topics: Anterior Chamber; Cataract Extraction; Cell Division; Corneal Diseases; Epithelium; Eye Enucleation;

1990
Subconjunctival 5-fluorouracil-induced transient striate melanokeratosis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:9

    Topics: Adult; Aged; Corneal Diseases; Fluorouracil; Humans; Keratosis; Melanosis; Middle Aged

1990
Topical application of 5-fluorouracil in premalignant lesions of cornea, conjunctiva and eyelid.
    Documenta ophthalmologica. Advances in ophthalmology, 1986, Dec-30, Volume: 64, Issue:1

    Topics: Aged; Carcinoma in Situ; Conjunctival Diseases; Corneal Diseases; Drug Administration Schedule; Eyel

1986
Complications of subconjunctival 5-fluorouracil following glaucoma filtering surgery.
    Ophthalmic surgery, 1987, Volume: 18, Issue:3

    Topics: Aged; Aged, 80 and over; Conjunctiva; Conjunctival Diseases; Corneal Diseases; Fluorouracil; Glaucom

1987
Serious corneal complications of glaucoma filtering surgery with postoperative 5-fluorouracil.
    American journal of ophthalmology, 1987, Feb-15, Volume: 103, Issue:2

    Topics: Aged; Corneal Diseases; Corneal Ulcer; Female; Fluorouracil; Glaucoma; Humans; Male; Middle Aged; Po

1987