fluorouracil has been researched along with Corneal Angiogenesis in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We conclude that there is greater risk of toxic anterior segment effects when mitomycin C is used as adjunctive therapy following filtration or pterygium surgery." | 1.29 | Ocular toxicity of mitomycin C and 5-fluorouracil in the rabbit. ( Feldman, F; Heathcote, JG; Ikeda-Douglas, JV; Morrow, GL; Stein, RM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morrow, GL | 1 |
| Stein, RM | 1 |
| Heathcote, JG | 1 |
| Ikeda-Douglas, JV | 1 |
| Feldman, F | 1 |
1 other study available for fluorouracil and Corneal Angiogenesis
| Article | Year |
|---|---|
Ocular toxicity of mitomycin C and 5-fluorouracil in the rabbit.
Topics: Animals; Corneal Edema; Corneal Neovascularization; Eye; Eyelids; Fluorouracil; Mitomycin; Necrosis; | 1994 |