Page last updated: 2024-10-27

fluorouracil and Cornea Injuries

fluorouracil has been researched along with Cornea Injuries in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gordon, SR1
Climie, M1
Hitt, AL1

Other Studies

1 other study available for fluorouracil and Cornea Injuries

ArticleYear
5-Fluorouracil interferes with actin organization, stress fiber formation and cell migration in corneal endothelial cells during wound repair along the natural basement membrane.
    Cell motility and the cytoskeleton, 2005, Volume: 62, Issue:4

    Topics: Actins; Animals; Basement Membrane; Cell Movement; Cornea; Corneal Injuries; Endothelium, Corneal; F

2005