Page last updated: 2024-10-27

fluorouracil and Contracture

fluorouracil has been researched along with Contracture in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Research Excerpts

ExcerptRelevanceReference
"We present a case of a 53-year-old female patient who was treated with 5-Fluorouracil (5-FU) after postsurgical contracture."4.02Contracture Treatment With 5-FU. ( Borrelli, M; Desales, A; Raskin, J; Talei, B, 2021)
"There was no recurrence (in six cases) and no side-effects seen in group A at final follow-up of 18."1.39Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket. ( Bodh, SA; Goel, R; Kamal, S; Kumar, S, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Talei, B1
Raskin, J1
Borrelli, M1
Desales, A1
Kamal, S1
Kumar, S1
Goel, R1
Bodh, SA1

Other Studies

2 other studies available for fluorouracil and Contracture

ArticleYear
Contracture Treatment With 5-FU.
    Ear, nose, & throat journal, 2021, Volume: 100, Issue:6_suppl

    Topics: Abscess; Anti-Bacterial Agents; Contracture; Dermatologic Agents; Drainage; Erythema; Face; Female;

2021
Serial sub-conjunctival 5-Fluorouracil for early recurrent anophthalmic contracted socket.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:12

    Topics: Adult; Anophthalmos; Antimetabolites; Conjunctiva; Contracture; Eye Enucleation; Eye, Artificial; Fl

2013