fluorouracil has been researched along with Constitutional Liver Dysfunction in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandalà, M | 1 |
| Cremonesi, M | 1 |
| Cazzaniga, M | 1 |
| Rezzani, C | 1 |
| Ghilardi, M | 1 |
| Mary, C | 1 |
| Ferretti, G | 1 |
| Barni, S | 1 |
| Komatsu, Y | 1 |
| Takei, M | 1 |
| Yuki, S | 1 |
| Fuse, N | 1 |
| Furukawa, S | 1 |
| Kato, T | 1 |
| Takeda, H | 1 |
| Kato, M | 1 |
| Asaka, M | 1 |
| Maciá Escalante, S | 1 |
| Rodríguez Lescure, A | 1 |
| Martínez Banaclocha, N | 1 |
| Gallego Plazas, J | 1 |
| Carrato Mena, A | 1 |
3 other studies available for fluorouracil and Constitutional Liver Dysfunction
| Article | Year |
|---|---|
Gilbert's syndrome and fluorouracil toxicity in colorectal cancer patients: which correlation?
Topics: Adult; Aged; Antineoplastic Agents; Camptothecin; Colorectal Neoplasms; Drug-Related Side Effects an | 2004 |
Treatment of a Gilbert's syndrome patient with irinotecan, leucovorin and 5-fluorouracil.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Fluorouracil; Gilbert Disease; G | 2005 |
[Patient with haemolytic anemia and treatment with capecitabine. Review of one case and literature].
Topics: Adult; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecita | 2006 |