Page last updated: 2024-10-27

fluorouracil and Condition, Preneoplastic

fluorouracil has been researched along with Condition, Preneoplastic in 104 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"A case of arsenical keratosis with multiple lesions of Bowen's disease and squamous cell carcinoma is described."7.72Successful treatment of multiple premalignant and malignant lesions in arsenical keratosis with a combination of acitretin and intralesional 5-fluorouracil. ( Khandpur, S; Sharma, VK, 2003)
"Three patients with biopsy-confirmed erythroplasia of Queyrat were treated with topically applied fluorouracil."7.65Erythroplasia of Queyrat. Treatment with topically applied fluorouracil. ( DeVillez, RL; Elgart, M; Goette, DK, 1975)
" Rat skin was observed for erythema and edema and the formulation was found safe for chronic use (p˃0."5.42Design, Development and Characterization of Topical Microemulsions of 5-Fluorouracil for the Treatment of Non Melanoma Skin Cancer and its Precursor Lesions. ( Kumar, S; Sinha, VR, 2015)
"We describe the successful treatment of porokeratosis of Mibelli of the left calf in an 83-year-old man with topical 5 percent imiquimod and topical 5 percent 5-fluorouracil."5.36Porokeratosis of Mibelli: Successful treatment with 5 percent topical imiquimod and topical 5 percent 5-fluorouracil. ( LeLeux, TM; Orengo, I; Rosen, T; Venkatarajan, S; Yang, D, 2010)
"Laser therapy appears the best option among nonsurgical approaches for actinic cheilitis, and PDT showed higher efficacy when sequentially combined with 5% imiquimod."5.05Treatments of actinic cheilitis: A systematic review of the literature. ( Cornacchia, L; Lai, M; Longo, C; Pampena, R; Pellacani, G; Peris, K, 2020)
"A case of arsenical keratosis with multiple lesions of Bowen's disease and squamous cell carcinoma is described."3.72Successful treatment of multiple premalignant and malignant lesions in arsenical keratosis with a combination of acitretin and intralesional 5-fluorouracil. ( Khandpur, S; Sharma, VK, 2003)
" Vitamin A acid and benzoyl peroxide have brought significant advances in the topical treatment of acne."3.66[Advances in topical therapy of skin diseases (author's transl)]. ( Happle, R, 1979)
"15 patients with superficial basaliomas or premalignant epithelial neoplastic disorders (actinic keratosis, leukoplakia, Bowen's disease) were treated locally over three weeks with retinoic acid (RA) alone or in combination with 5-fluorouracil (5-FU)."3.66[Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil]. ( Kurka, M; Orfanos, CE; Pullmann, H, 1978)
"Three patients with biopsy-confirmed erythroplasia of Queyrat were treated with topically applied fluorouracil."3.65Erythroplasia of Queyrat. Treatment with topically applied fluorouracil. ( DeVillez, RL; Elgart, M; Goette, DK, 1975)
" Here, we investigated the efficacy of calcipotriol, a topical TSLP inducer, in combination with 5-fluorouracil (5-FU) as an immunotherapy for actinic keratosis."2.84Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy. ( Cornelius, LA; Cunningham, TJ; Demehri, S; Eliane, JP; Kopan, R; Manivasagam, S; Mirzaalian, H; Saavedra, AP; Schaffer, A; Tabacchi, M; Tuchayi, SM; Turkoz, A; Wallendorf, M, 2017)
"In the future, the treatment of actinic keratosis can be more often done in primary health care."2.52[Diagnosis and treatment of actinic keratosis]. ( Isoherranen, K; Koskenmies, S; Overmark, M; Pitkänen, S; Saksela, O; Ylitalo, L, 2015)
"Actinic keratosis is a precancerous lesion that is commonly seen in the elderly patient and requires treatment."2.43[Actinic keratosis]. ( Dissemond, J; Grabbe, S, 2006)
"Actinic keratosis is currently believed to be an early stage in the evolution of squamous cell carcinoma."2.42Topical and light-based treatments for actinic keratoses. ( Alam, M; Goldberg, LH; Silapunt, S, 2003)
"The ability to manage non-melanoma skin cancers and pre-malignant lesions with topical pharmacologic agents is highly compelling."2.42Topical treatment strategies for non-melanoma skin cancer and precursor lesions. ( Fein, H; McGillis, ST, 2004)
"Actinic cheilitis is a common premalignant condition, significant for symptoms and potential development into invasive squamous cell carcinoma."2.40Actinic cheilitis. A treatment review. ( Curlin, MU; Dufresne, RG, 1997)
" Physiological information of treatment response derived via diffuse reflectance spectroscopy (DRS) from murine primary CRC tumors provide a better understanding for the development of new drugs and dosing strategies in CRC."1.56Diffuse reflectance spectroscopy to monitor murine colorectal tumor progression and therapeutic response. ( Bullard, EA; Fahr, MJ; Greening, GJ; Hale, LN; Muldoon, TJ; Mundo, AI; Rajaram, N, 2020)
"The cost of topical treatments for actinic keratosis (AK) has historically been evaluated in relation to the number of lesions requiring treatment or simply by the price of a single tube/sachet of the drug used."1.51Evaluation of the treatment costs and duration of topical treatments for multiple actinic keratosis based on the area of the cancerization field and not on the number of lesions. ( Calzavara-Pinton, P; Hamon, P; Tanova, N, 2019)
" Rat skin was observed for erythema and edema and the formulation was found safe for chronic use (p˃0."1.42Design, Development and Characterization of Topical Microemulsions of 5-Fluorouracil for the Treatment of Non Melanoma Skin Cancer and its Precursor Lesions. ( Kumar, S; Sinha, VR, 2015)
" DMH was given to fish by intraperitoneal injection in a dosage of 15 mg/kg body weight once a week for 6 weeks."1.37[Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine]. ( Kakuta, I; Takase, K, 2011)
"We describe the successful treatment of porokeratosis of Mibelli of the left calf in an 83-year-old man with topical 5 percent imiquimod and topical 5 percent 5-fluorouracil."1.36Porokeratosis of Mibelli: Successful treatment with 5 percent topical imiquimod and topical 5 percent 5-fluorouracil. ( LeLeux, TM; Orengo, I; Rosen, T; Venkatarajan, S; Yang, D, 2010)
"Final diagnosis stated a multilocular metastasising gastric cancer with infiltration of bone, peritoneum and dura and signet-cell infiltration of the bone marrow."1.31[Hemorrhagic diathesis as initial symptom of stomach carcinoma]. ( Dempke, W; Kellner, O; Schmoll, HJ; von Poblozki, A; Wolf, HH, 2000)
"5-Fluorouracil was used at 3."1.30Destructive procedures are the standard of care for treatment of actinic keratoses. ( Feldman, SR; Fleischer, AB; Jorizzo, JL; Williford, PM, 1999)

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-199059 (56.73)18.7374
1990's6 (5.77)18.2507
2000's14 (13.46)29.6817
2010's22 (21.15)24.3611
2020's3 (2.88)2.80

Authors

AuthorsStudies
Lai, M1
Pampena, R1
Cornacchia, L1
Pellacani, G1
Peris, K1
Longo, C1
Gupta, S2
Jangra, RS1
Gupta, SS1
Gujrathi, AV1
Mundo, AI1
Greening, GJ1
Fahr, MJ1
Hale, LN1
Bullard, EA1
Rajaram, N1
Muldoon, TJ1
Walker, JL1
Siegel, JA1
Sachar, M1
Pomerantz, H1
Chen, SC1
Swetter, SM1
Dellavalle, RP1
Stricklin, GP1
Qureshi, AA1
DiGiovanna, JJ1
Weinstock, MA2
Al-Haseni, A1
Chitgopeker, P1
Ho, JD1
Goldberg, LJ1
Sahni, D1
Radyk, MD1
Burclaff, J1
Willet, SG1
Mills, JC1
Calzavara-Pinton, P1
Tanova, N1
Hamon, P1
Routray, S1
Dikhit, PS1
Rajani, BC1
Khan, MM1
Beatson, M1
Means, AD1
Leader, NF1
Robinson-Bostom, L1
Samrao, A1
Cockerell, CJ3
Borycka-Kiciak, K1
Białas, A1
Wejman, J1
Uchman-Musielak, M1
Tarnowski, W1
Isoherranen, K1
Koskenmies, S1
Overmark, M1
Ylitalo, L1
Saksela, O1
Pitkänen, S1
Kumar, S1
Sinha, VR1
Veloz-Martínez, MG1
Quintana-Romero, V1
Contreras-Morales, Mdel R1
Jiménez-Vieyra, CR1
Cunningham, TJ1
Tabacchi, M1
Eliane, JP1
Tuchayi, SM1
Manivasagam, S1
Mirzaalian, H1
Turkoz, A1
Kopan, R1
Schaffer, A1
Saavedra, AP1
Wallendorf, M1
Cornelius, LA1
Demehri, S1
Endrizzi, BT1
Lee, PK1
Fenske, NA1
Spencer, J1
Adam, F1
Terushkin, V1
Braga, JC1
Dusza, SW1
Scope, A1
Busam, K1
Marghoob, AA1
Gill, M1
Halpern, AC1
Shah, AY1
Doherty, SD1
Rosen, T2
Venkatarajan, S1
LeLeux, TM1
Yang, D1
Orengo, I1
Takase, K1
Kakuta, I1
Jadotte, YT1
Schwartz, RA2
Fox, PA1
Schmutz, JL1
Trechot, P1
Esmann, S1
Jemec, GB1
Robins, P1
Gupta, AK1
Tutrone, WD1
Saini, R1
Caglar, S1
Weinberg, JM1
Crespo, J1
Marcus, L1
Silapunt, S1
Goldberg, LH1
Alam, M1
Khandpur, S1
Sharma, VK1
McGillis, ST1
Fein, H1
Sorio, C1
Capelli, P1
Lissandrini, D1
Moore, PS1
Balzarini, P1
Falconi, M1
Zamboni, G1
Scarpa, A1
Dissemond, J1
Grabbe, S1
Perrett, CM1
McGregor, JM1
Warwick, J1
Karran, P1
Leigh, IM1
Proby, CM1
Harwood, CA1
Zide, MF1
Borchard, F1
Klein, E5
Holtermann, OA1
Helm, F3
Milgrom, H3
Stoll, HL3
Rosner, D1
Klein, LE1
Burgess, G2
Lin, PZ2
Cai, HY1
Shu, YJ1
Wang, GQ1
Wu, AR1
Liu, SF1
Li, MX1
Dufresne, RG1
Curlin, MU1
Barnaby, JW1
Styles, AR1
Fowble, B1
Hanlon, AL1
Patchefsky, A1
Freedman, G1
Hoffman, JP1
Sigurdson, ER1
Goldstein, LJ1
Pritchard, DM1
Potten, CS1
Hickman, JA1
Feldman, SR1
Fleischer, AB1
Williford, PM1
Jorizzo, JL1
Evans, C1
Dempke, W1
von Poblozki, A1
Kellner, O1
Wolf, HH1
Schmoll, HJ1
Podzamczer, D1
Miralles, P1
La Calle Md, Md1
Zarco, C1
Berenguer, J1
López Aldeguer, J1
Valencia, E1
Rubio, R1
Ribera, JM1
Katz, H1
Redding, KG1
Happle, R1
Cullen, SI1
Golden, GT1
Rosenthal, JD1
Shaw, A1
Melski, JW1
Kurka, M1
Orfanos, CE1
Pullmann, H1
Goette, DK3
Gartmann, H1
Medina, D1
Shepherd, F1
Jansen, GT2
Sturm, JT1
Christenson, CE1
Uecker, JH1
Perry, JF1
Elgart, M1
DeVillez, RL1
Levin, B1
Karlin, DA1
Schulman, S1
Thorp, GW1
Kirsner, JB1
Rosenberg, IH1
Poljacki, M1
Stojanović, S1
Svilar, V1
de Keizer, RJ1
de Wolff-Rouendaal, D1
van Delft, JL1
Hughes, RR1
von Koppenfels, R1
Müller, RP1
Farah, FS1
Shbaklo, Z1
Lynch, PJ1
Lowenfels, AB1
Zala, L1
Lapsa, RKh1
Graham, JH1
Helwig, EB1
Dean, RE1
Taylor, ES1
Weisbrod, DM1
Martin, JW1
Riedel, B1
Brosig, W1
Nagel, R1
Pust, R1
Goto, M1
Muramoto, S1
Nakagaki, K1
Zackheim, HS1
Farber, EM1
Miller, E1
Walker, MJ1
Trnka, J1
Ott, F3
Chevrel, B1
Chevrel, JP1
Storck, H2
Eller, JJ1
Epstein, E1
Uthida-Tanaka, AM1
Nakamura, S1
de Britto-Costa, R1
de Tavares Mello, E1
Ebner, H1
Williams, AC1
Landes, E1
Schuppli, R1
Basset, A1
Grosshans, E1
Maleville, J1
Eichenberger-De Beer, H1
Achten, G1
Van Oost, A1
Ledoux-Corbusier, M1
Midana, A1
Leigheb, G1
Llombart Bosch, M1
Espinosa Cabañero, JA1
Lewis, RJ1
Bendl, BJ1
Fulton, JE1
Carter, DM1
Hurley, HJ1
Rossman, RE1
Hueser, JN1
Strand, ME1
Pugh, RP1
Weitgasser, H1
Anderson, FE1
Johnson, AM1
Havyatt, MT1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial[NCT00847912]Phase 4954 participants (Actual)Interventional2009-06-26Completed
Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention: A Long-term (3 Years) Follow-up of Prospective, Randomized, Multicenter-clinical Trial[NCT03642535]Phase 4300 participants (Anticipated)Interventional2018-08-30Recruiting
The Role of Calcipotriol in Treatment of Pre-cancerous Skin Lesions[NCT02019355]Early Phase 1132 participants (Actual)Interventional2013-10-31Completed
Combination Topical 5-fluorouracil 5% / Calcipotriene 0.005% Cream for Treatment of in Situ and Superficially Invasive Squamous Cell Carcinoma of the Skin[NCT04839731]Early Phase 130 participants (Anticipated)Interventional2021-04-14Recruiting
Combination Calcipotriene 0.005% Foam and Fluorouracil 5% Cream for the Treatment of Actinic Keratoses on the Scalp[NCT03996252]Early Phase 115 participants (Actual)Interventional2019-07-01Terminated (stopped due to The study team was not able to start the study and they never completed the IRB submission, so the study was terminated.)
Calcipotriol Plus 5-Fluorouracil Immunotherapy for Skin Cancer Prevention in Organ Transplant Recipients[NCT04642287]Phase 264 participants (Anticipated)Interventional2026-01-31Not yet recruiting
Calcipotriol Plus 5-Flourouracil Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients[NCT04329221]Phase 262 participants (Anticipated)Interventional2026-01-01Not yet recruiting
Efficacy and Safety of Topical Trichloroacetic Acid vs. Electrocautery for the Treatment of Anal Intraepithelial Neoplasia in HIV-positive Patients (TECAIN) - a Randomized Controlled Trial[NCT02615860]560 participants (Actual)Interventional2015-11-30Completed
Pilot Study of the Pragmatic Use of Mobile Phone Based Follow up of Actinic Keratoses Treated With Topical 5-fluorouracil[NCT02938715]26 participants (Actual)Interventional2016-10-31Completed
Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358]Phase 149 participants (Actual)Interventional2019-03-23Terminated (stopped due to Study terminated because of COVID19 pandemics.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hazard Ratio for Surgically Treated KC

(NCT00847912)
Timeframe: date of randomization to last visit before end of study follow up (6/30/2013), assessed up to four years

Interventionparticipants (Number)
Arm 1: 5-fluorouracil182
Arm 2: Placebo, Vehicle Control177

The Time to Diagnosis of the First Keratinocyte Carcinoma (KC) on the Face or Ears for Which Surgery is Performed

Diagnosis of the first Primary Basil Cell Carcinoma (BCC) or primary Squamous Cell Carcinoma (SCC) on the face or ears that was removed surgically. (NCT00847912)
Timeframe: From randomization to last visit prior to end of study date (6/30/2013), assessed up to four years

Interventionyears (Median)
Arm 1: 5-fluorouracil3.37
Arm 2: Placebo, Vehicle Control3.52

Reviews

18 reviews available for fluorouracil and Condition, Preneoplastic

ArticleYear
Treatments of actinic cheilitis: A systematic review of the literature.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:3

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Dermabrasion; D

2020
Pharmacotherapeutic management of actinic keratosis: focus on newer topical agents.
    American journal of clinical dermatology, 2013, Volume: 14, Issue:4

    Topics: Administration, Topical; Aminoquinolines; Cryotherapy; Diclofenac; Dose-Response Relationship, Drug;

2013
[Diagnosis and treatment of actinic keratosis].
    Duodecim; laaketieteellinen aikakauskirja, 2015, Volume: 131, Issue:9

    Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Ag

2015
Actinic keratoses: past, present and future.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:5 Suppl OD

    Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamou

2010
Actinic cheilitis: a treatment review.
    International journal of dermatology, 2010, Volume: 49, Issue:11

    Topics: Aminoquinolines; Antineoplastic Agents; Carcinoma, Squamous Cell; Caustics; Cheilitis; Cryosurgery;

2010
Treatment options for anal intraepithelial neoplasia and evidence for their effectiveness.
    Sexual health, 2012, Volume: 9, Issue:6

    Topics: Adult; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Anus Neoplasms; Cido

2012
The use of topical fluorouracil to treat actinic keratosis.
    Cutis, 2002, Volume: 70, Issue:2 Suppl

    Topics: Administration, Topical; Antimetabolites, Antineoplastic; Dermatologic Agents; Fluorouracil; Humans;

2002
Topical therapy for actinic keratoses, I: 5-Fluorouracil and imiquimod.
    Cutis, 2003, Volume: 71, Issue:5

    Topics: Administration, Cutaneous; Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents;

2003
Topical and light-based treatments for actinic keratoses.
    Seminars in cutaneous medicine and surgery, 2003, Volume: 22, Issue:3

    Topics: Adjuvants, Immunologic; Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Antineoplasti

2003
Topical treatment strategies for non-melanoma skin cancer and precursor lesions.
    Seminars in cutaneous medicine and surgery, 2004, Volume: 23, Issue:3

    Topics: Administration, Topical; Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Ag

2004
[Actinic keratosis].
    MMW Fortschritte der Medizin, 2006, Jun-15, Volume: 148, Issue:24

    Topics: Adjuvants, Immunologic; Age Factors; Aged; Aminoquinolines; Antimetabolites, Antineoplastic; Antineo

2006
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C

1982
Therapeutic perspectives in actinic and other keratoses.
    International journal of dermatology, 1996, Volume: 35, Issue:8

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Cryosurgery; Fluorouracil; Humans; Kerat

1996
Actinic cheilitis. A treatment review.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1997, Volume: 23, Issue:1

    Topics: Cheilitis; Cryosurgery; Electrocoagulation; Fluorouracil; Humans; Laser Therapy; Precancerous Condit

1997
Actinic keratoses. Differential diagnosis and treatment.
    Drugs & aging, 1997, Volume: 11, Issue:3

    Topics: Aging; Chemexfoliation; Combined Modality Therapy; Cryosurgery; Curettage; Dermabrasion; Diagnosis,

1997
[Recommendations of GESIDA/Spanish National Plan of AIDS on diagnosis and treatment of Kaposi's sarcoma and cervical cancer in HIV-infected patients].
    Medicina clinica, 2002, Jun-01, Volume: 118, Issue:20

    Topics: Acquired Immunodeficiency Syndrome; Algorithms; Antimetabolites, Antineoplastic; Antineoplastic Agen

2002
Review of erythroplasia of Queyrat and its treatment.
    Urology, 1976, Volume: 8, Issue:4

    Topics: Adult; Aged; Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penile Neoplasms; Precancerous

1976
Topical antimetabolites.
    Annual review of medicine, 1970, Volume: 21

    Topics: Antimetabolites; Antineoplastic Agents; Carcinoma, Basal Cell; Fluorouracil; Folic Acid Antagonists;

1970

Trials

4 trials available for fluorouracil and Condition, Preneoplastic

ArticleYear
Characteristics of Keratinocyte Carcinomas and Patients with Keratinocyte Carcinomas Following a Single 2-4 Week Course of Topical 5-fluorouracil on the Face and Ears.
    Acta dermato-venereologica, 2019, Jun-01, Volume: 99, Issue:7

    Topics: Administration, Topical; Aged; Aged, 80 and over; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; D

2019
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
    The Journal of clinical investigation, 2017, 01-03, Volume: 127, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Animals; Antineoplastic Combined Chemotherapy Prot

2017
Treatment of post-transplant premalignant skin disease: a randomized intrapatient comparative study of 5-fluorouracil cream and topical photodynamic therapy.
    The British journal of dermatology, 2007, Volume: 156, Issue:2

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Bowen's Disease

2007
The effects of 5-fluorouracil (5-FU) ointment in the treatment of neoplastic dermatoses.
    Dermatologica, 1970, Volume: 140

    Topics: Clinical Trials as Topic; Fluorouracil; Humans; Neoplasm Metastasis; Ointments; Precancerous Conditi

1970

Other Studies

82 other studies available for fluorouracil and Condition, Preneoplastic

ArticleYear
A novel method to enhance efficacy of topical drugs by condom occlusion in penile dermatoses.
    Postgraduate medical journal, 2020, Volume: 96, Issue:1135

    Topics: Administration, Topical; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Balanitis; Condo

2020
Diffuse reflectance spectroscopy to monitor murine colorectal tumor progression and therapeutic response.
    Journal of biomedical optics, 2020, Volume: 25, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Colorectal Neoplasms; Disease Models, A

2020
5-Fluorouracil for Actinic Keratosis Treatment and Chemoprevention: A Randomized Controlled Trial.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:6

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Double

2017
5-Fluorouracil for Actinic Keratosis Treatment and Chemoprevention: A Randomized Controlled Trial.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:6

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Double

2017
5-Fluorouracil for Actinic Keratosis Treatment and Chemoprevention: A Randomized Controlled Trial.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:6

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Double

2017
5-Fluorouracil for Actinic Keratosis Treatment and Chemoprevention: A Randomized Controlled Trial.
    The Journal of investigative dermatology, 2017, Volume: 137, Issue:6

    Topics: Administration, Cutaneous; Antimetabolites, Antineoplastic; Dose-Response Relationship, Drug; Double

2017
Amelanotic melanoma arising within a lesion of disseminated superficial actinic porokeratosis: An unusual presentation leading to a novel therapeutic approach.
    Dermatologic therapy, 2018, Volume: 31, Issue:1

    Topics: Administration, Cutaneous; Aged; Antimetabolites, Antineoplastic; Bandages; Biopsy; Cell Transformat

2018
Metaplastic Cells in the Stomach Arise, Independently of Stem Cells, via Dedifferentiation or Transdifferentiation of Chief Cells.
    Gastroenterology, 2018, Volume: 154, Issue:4

    Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Cell Lineage; Cell Proliferation; Cell Transdifferentiat

2018
Evaluation of the treatment costs and duration of topical treatments for multiple actinic keratosis based on the area of the cancerization field and not on the number of lesions.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:2

    Topics: Administration, Topical; Aminolevulinic Acid; Cohort Studies; Cost of Illness; Diclofenac; Diterpene

2019
Can topical 5-fluorouracil be used as a viable treatment option for oral premalignant lesions and tumors?
    Oral oncology, 2019, Volume: 91

    Topics: Administration, Topical; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male; Precan

2019
Perianal infection of highly oncogenic human papilloma virus: how to prevent from cancer? Case report.
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2015, Volume: 68, Issue:2

    Topics: Anal Canal; Anus Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Hemorrhoidectomy; He

2015
Design, Development and Characterization of Topical Microemulsions of 5-Fluorouracil for the Treatment of Non Melanoma Skin Cancer and its Precursor Lesions.
    Anti-cancer agents in medicinal chemistry, 2015, Volume: 16, Issue:2

    Topics: Administration, Cutaneous; Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relatio

2015
[Treatment results for different categories of vaginal intraepithelial neoplasia with electrocoagulation, 5-fluorouracil and combined treatment].
    Ginecologia y obstetricia de Mexico, 2015, Volume: 83, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma in Situ; Carcinoma, Squam

2015
Management of carcinoma of the skin in solid organ transplant recipients with oral capecitabine.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:10

    Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Fluorourac

2009
Over the last several years, I've had several small spots of skin on my shoulder cut out due to skin cancer concerns. Now, my doctor say I have precancerous areas on my face that need treatment, but he's recommending I use a cream. Is that likely to wor
    Mayo Clinic health letter (English ed.), 2010, Volume: 28, Issue:6

    Topics: Administration, Topical; Antimetabolites, Antineoplastic; Face; Fluorouracil; Humans; Precancerous C

2010
Agreement on the clinical diagnosis and management of cutaneous squamous neoplasms.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2010, Volume: 36, Issue:10

    Topics: Algorithms; Aminoquinolines; Biopsy; Carcinoma in Situ; Carcinoma, Squamous Cell; Cryosurgery; Curet

2010
Porokeratosis of Mibelli: Successful treatment with 5 percent topical imiquimod and topical 5 percent 5-fluorouracil.
    Dermatology online journal, 2010, Dec-15, Volume: 16, Issue:12

    Topics: Administration, Cutaneous; Aged, 80 and over; Aminoquinolines; Antimetabolites; Carcinoma, Basal Cel

2010
[Chemopreventive effects of 5-fluorouracil and lactoferrin on goldfish intestinal carcinogenesis induced by 1,2-dimethylhydrazine].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:10

    Topics: 1,2-Dimethylhydrazine; Animals; Anti-Infective Agents; Antimetabolites, Antineoplastic; Blood Cell C

2011
Solar cheilosis: an ominous precursor part II. Therapeutic perspectives.
    Journal of the American Academy of Dermatology, 2012, Volume: 66, Issue:2

    Topics: Administration, Topical; Aminoquinolines; Biopsy; Carcinoma, Squamous Cell; Cheilitis; Combined Moda

2012
[Resolution of actinic keratosis with capecetabin].
    Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:11

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Capecitabine; Colonic Neoplasms; Deoxycytidine; Fluorou

2012
Patients' perceptions of topical treatments of actinic keratosis.
    The Journal of dermatological treatment, 2014, Volume: 25, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents; Diclofenac

2014
Photodynamic therapy for actinic keratosis followed by 5-fluorouracil reaction.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2003, Volume: 29, Issue:10

    Topics: Aminolevulinic Acid; Antimetabolites, Antineoplastic; Emollients; Female; Fluorouracil; Humans; Kera

2003
Successful treatment of multiple premalignant and malignant lesions in arsenical keratosis with a combination of acitretin and intralesional 5-fluorouracil.
    The Journal of dermatology, 2003, Volume: 30, Issue:10

    Topics: Acitretin; Arsenic; Biopsy, Needle; Bowen's Disease; Carcinoma, Squamous Cell; Drug Therapy, Combina

2003
Mucinous cystic carcinoma of the pancreas: a unique cell line and xenograft model of a preinvasive lesion.
    Virchows Archiv : an international journal of pathology, 2005, Volume: 446, Issue:3

    Topics: Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cystadenocarcinoma, Mucinous; Disease Models

2005
Actinic keratosis: from the skin to the lip.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:6

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemexfoliation; Cryosurgery; Elec

2008
Topical therapy for cutaneous tumors.
    Transplantation proceedings, 1984, Volume: 16, Issue:2

    Topics: Administration, Topical; Antineoplastic Agents; Fluorouracil; Humans; Hypersensitivity; Immunotherap

1984
[Treatment of marked epithelial dysplasia of esophagus. II. Microspectophotometric studies on DNA content in epithelial cells of esophagus treated with antitumor B III or tilorone (author's transl)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1981, Volume: 3, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; DNA, Neoplasm; Drug Combinations; Drugs, Chinese Herbal; Epitheli

1981
[Therapy of severe epithelial dysplasia of esophagus. I. Therapeutic effects of Antitumor B III, Antitumor B and tilorone (author's transl)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1980, Volume: 2, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents, Phytogenic; Drug Combinations; Drugs, Chinese Herbal; Esophag

1980
The presence of proliferative breast disease with atypia does not significantly influence outcome in early-stage invasive breast cancer treated with conservative surgery and radiation.
    International journal of radiation oncology, biology, physics, 1998, Aug-01, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neopl

1998
The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia.
    Cancer research, 1998, Dec-01, Volume: 58, Issue:23

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Division; Colon; Cyclin-Dependent Kinase I

1998
Destructive procedures are the standard of care for treatment of actinic keratoses.
    Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:1

    Topics: Antimetabolites, Antineoplastic; Florida; Fluorouracil; Health Care Surveys; Humans; Keratosis; Medi

1999
Actinic keratosis: time to call a spade a spade.
    Southern medical journal, 2000, Volume: 93, Issue:7

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Epidermis; Fluorouracil; Humans; Keratino

2000
[Hemorrhagic diathesis as initial symptom of stomach carcinoma].
    Wiener klinische Wochenschrift, 2000, Dec-22, Volume: 112, Issue:24

    Topics: Algorithms; Anemia, Hemolytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplasti

2000
Therapeutic challenge of premalignant and malignant skin lesions.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Acetates; Adrenal Cortex Hormones; Adult; Aged; Balanitis; Bowen's Disease; Clioquinol; Cryosurgery;

1975
[Advances in topical therapy of skin diseases (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1979, Jan-26, Volume: 121, Issue:4

    Topics: Acne Vulgaris; Administration, Topical; Alopecia; Benzoyl Peroxide; Dinitrochlorobenzene; Fluocortol

1979
Topical fluorouracil therapy for precancers and cancers of the skin.
    Journal of the American Geriatrics Society, 1979, Volume: 27, Issue:12

    Topics: Administration, Topical; Drug Eruptions; Fluorouracil; Humans; Keratosis; Precancerous Conditions; S

1979
Carcinoma of the rectum in adolescence.
    American journal of diseases of children (1960), 1975, Volume: 129, Issue:6

    Topics: Adenocarcinoma, Mucinous; Adolescent; Age Factors; Cyclophosphamide; Fluorouracil; Humans; Hydroneph

1975
Surgical treatment of erythroplasia of Queyrat.
    Plastic and reconstructive surgery, 1978, Volume: 61, Issue:2

    Topics: Erythroplasia; Fluorouracil; Humans; Male; Precancerous Conditions

1978
[Vitamin A acid for the topical management of epithelial neoplasms. Combination with 5-fluorouracil].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1978, Volume: 29, Issue:6

    Topics: Aged; Carcinoma, Basal Cell; Drug Therapy, Combination; Female; Fluorouracil; Humans; Keratosis; Leu

1978
[Topical use of antineoplastic agents in precancerous conditions of the skin].
    Zeitschrift fur Hautkrankheiten, 1977, Apr-15, Volume: 52, Issue:8

    Topics: Administration, Topical; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Kera

1977
Enhancement and inhibition of mammary tumor formation and growth by cytostatic drugs.
    Cancer research, 1977, Volume: 37, Issue:10

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Female; Fluorouracil; Mammary Neoplasms, Experimen

1977
Practical therapy for hyperkeratotic skin lesions.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Acetates; Aged; Bandages; Callosities; Electrosurgery; Female; Fluorouracil; Foot; Humans; Keratoaca

1975
Squamous-cell carcinoma of the anus arising in a giant condyloma acuminatum: report of a case.
    Diseases of the colon and rectum, 1975, Volume: 18, Issue:2

    Topics: Administration, Topical; Anal Canal; Anus Diseases; Anus Neoplasms; Carcinoma, Squamous Cell; Condyl

1975
Erythroplasia of Queyrat. Treatment with topically applied fluorouracil.
    JAMA, 1975, Jun-02, Volume: 232, Issue:9

    Topics: Administration, Topical; Aged; Biopsy; Erythroplasia; Fluorouracil; Humans; Male; Middle Aged; Penil

1975
The gasteointestinal oncology clinic. A multidisciplinary approach to cancer diagnosis and management at a University Medical Center.
    The Surgical clinics of North America, 1976, Volume: 56, Issue:1

    Topics: Adenocarcinoma; Colitis, Ulcerative; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination;

1976
[The importance of local administration of 5% 5-fluorouracil in the therapy of senile keratoses and basocellular carcinoma].
    Medicinski pregled, 1989, Volume: 42, Issue:3-4

    Topics: Administration, Topical; Aged; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Keratosis; Male;

1989
Topical application of 5-fluorouracil in premalignant lesions of cornea, conjunctiva and eyelid.
    Documenta ophthalmologica. Advances in ophthalmology, 1986, Dec-30, Volume: 64, Issue:1

    Topics: Aged; Carcinoma in Situ; Conjunctival Diseases; Corneal Diseases; Drug Administration Schedule; Eyel

1986
Early diagnosis and management of premalignant lesions and early invasive cancers of the vulva.
    Southern medical journal, 1971, Volume: 64, Issue:12

    Topics: Adult; Aged; Carcinoma; Female; Fluorouracil; Follow-Up Studies; Humans; Middle Aged; Neoplasm Metas

1971
[Clinical picture and radiotherapy of malignant vulvar neoplasms].
    Strahlentherapie, 1973, Volume: 146, Issue:5

    Topics: Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Melanoma; Middle A

1973
The treatment of premalignant and malignant skin lesions with 5-fluorouracil.
    Le Journal medical libanais. The Lebanese medical journal, 1971, Volume: 24, Issue:1

    Topics: Drug Eruptions; Female; Fluorouracil; Humans; Keratosis; Male; Precancerous Conditions; Skin; Skin N

1971
Tumors of the skin. Premalignment and malignant.
    Minnesota medicine, 1974, Volume: 57, Issue:10

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Diagnosis, Differential; Fluorouracil; Humans; Kera

1974
Local chemotherapy of skin cancer.
    Panminerva medica, 1974, Volume: 16, Issue:3

    Topics: Administration, Topical; Fluorouracil; Humans; Precancerous Conditions; Skin Neoplasms

1974
[Histological findings during the treatment of skin neoplasias with 5-fluorouracil ointment].
    Dermatologica, 1972, Volume: 145, Issue:5

    Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Melanoma; Middl

1972
[The reactivity of the RES in cancer of the gastrointestinal tract and during treatment with fluorofur].
    Voprosy onkologii, 1972, Volume: 18, Issue:12

    Topics: Achlorhydria; Adult; Aged; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Furans; Go

1972
Erythroplasia of Queyrat. A clinicopathologic and histochemical study.
    Cancer, 1973, Volume: 32, Issue:6

    Topics: Adult; Age Factors; Aged; Biopsy; Erythroplasia; Ethnicity; Female; Fluorouracil; Histocytochemistry

1973
Proceedings: Chemotherapy and immunotherapy for cancer involving the skin.
    Proceedings. National Cancer Conference, 1972, Volume: 7

    Topics: Administration, Topical; Antigens, Bacterial; Antineoplastic Agents; Carcinoma, Basal Cell; Carcinom

1972
Letter: Erythroplasia of Queyrat.
    Archives of dermatology, 1974, Volume: 109, Issue:4

    Topics: Erythroplasia; Fluorouracil; Humans; Precancerous Conditions

1974
The treatment of premalignant and malignant lesions of the vulva.
    American journal of obstetrics and gynecology, 1974, May-01, Volume: 119, Issue:1

    Topics: Administration, Topical; Adult; Aged; Carcinoma in Situ; Carcinoma, Squamous Cell; Female; Fluoroura

1974
[Preoperative treatment of the carcinoma of the urinary bladder (author's transl)].
    Der Urologe. Ausg. A, 1974, Volume: 13, Issue:2

    Topics: Bone Marrow; Cystitis; Diarrhea; Fluorouracil; Humans; Precancerous Conditions; Preoperative Care; R

1974
[Experience with 5-fluorouracil in malignant skin tumors].
    Gan no rinsho. Japan journal of cancer clinics, 1967, Volume: 13, Issue:11

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Male

1967
Topical therapy with 5-Fluorouracil.
    Journal of surgical oncology, 1971, Volume: 3, Issue:3

    Topics: DNA; Fluorouracil; Humans; Keratosis; Pharmaceutical Vehicles; Precancerous Conditions; Propylene Gl

1971
Tumors of the skin. XII. Topical 5-Fluorouracil for epidermal neoplasms.
    Journal of surgical oncology, 1971, Volume: 3, Issue:3

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatitis; Esthetics; Female; Fluorouracil; Humans

1971
[Topical therapy of superficial basalioma and senile keratoma with 5-fluorouracil].
    Ceskoslovenska dermatologie, 1971, Volume: 46, Issue:5

    Topics: Aged; Carcinoma, Basal Cell; Fluorouracil; Humans; Keratosis; Precancerous Conditions; Skin Neoplasm

1971
[Trials using local 5-FU therapy in precancerous states and cancer of the skin].
    Dermatologica, 1971, Volume: 142, Issue:5

    Topics: Carcinoma, Basal Cell; Fluorouracil; Follow-Up Studies; Humans; Keratosis; Ointments; Precancerous C

1971
[Gallbladder cancer].
    La Presse medicale, 1971, Dec-04, Volume: 79, Issue:52

    Topics: Adenocarcinoma; Adenoma; Carcinoma; Cholelithiasis; Fluorouracil; Gallbladder Neoplasms; Humans; Mel

1971
[5-Fluorouracil in local therapy of precancerous conditions and carcinoma of the skin].
    Schweizerische medizinische Wochenschrift, 1971, Aug-28, Volume: 101, Issue:34

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Keratosis; Neoplasm Recurrenc

1971
Topical fluorouracil (5-FU) for premalignant keratoses.
    The Medical letter on drugs and therapeutics, 1971, May-28, Volume: 13, Issue:11

    Topics: Fluorouracil; Humans; Keratosis; Precancerous Conditions

1971
Cancer and precancer of the skin, review of 40 years experience in therapy.
    IMS, Industrial medicine and surgery, 1971, Volume: 40, Issue:1

    Topics: Carcinoma, Squamous Cell; Fluorouracil; Humans; Methods; Precancerous Conditions; Radiotherapy Dosag

1971
Treatment of precancerous dermatoses with topical 5-Fluorouracil.
    Asthetische Medizin, 1969, Jul-20, Volume: 18, Issue:7

    Topics: Fluorouracil; Humans; Keratosis; Ointments; Precancerous Conditions; Skin Diseases; Solutions

1969
[Topical therapy of precancerous lesions and skin carcinomas using a 5-fluorouracil ointment].
    Hospital (Rio de Janeiro, Brazil), 1969, Volume: 76, Issue:6

    Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Female; Fluorouracil

1969
[New possibilities in the treatment of epithelioma].
    Wiener klinische Wochenschrift, 1969, Nov-04, Volume: 81, Issue:46

    Topics: Animals; Fluorouracil; Humans; Precancerous Conditions; Rats; Skin Neoplasms; Thymine; Uracil

1969
Experiences with local chemotherapy and immunotherapy in premalignant and malignant skin lesions.
    Cancer, 1970, Volume: 25, Issue:2

    Topics: Antigen-Antibody Reactions; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatitis; Dermatitis,

1970
[Treatment of carcinoma and precancerosis using 5-fluorouracil].
    Archiv fur klinische und experimentelle Dermatologie, 1970, Volume: 237, Issue:1

    Topics: Aged; Carcinoma; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Keratosis; Occlusive Dressings

1970
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
    Minerva medica, 1970, Jul-11, Volume: 61, Issue:55

    Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive

1970
[Our experience with the local chemotherapy of cutaneous precancerous conditions, epithelioma and of kerato-acanthoma].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:1

    Topics: Colchicine; Diagnosis, Differential; Fluorouracil; Humans; Keratoacanthoma; Ointments; Precancerous

1970
The local treatment of precancerous skin conditions with 5-fluorouracil ointment.
    Dermatologica, 1970, Volume: 140

    Topics: Fluorouracil; Humans; Ointments; Precancerous Conditions; Skin Neoplasms; Time Factors

1970
5-fluorouracil (5-FU) ointment in the treatment of basal cell epithelioma. Histological control over a long duration.
    Dermatologica, 1970, Volume: 140

    Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Male; Middle Ag

1970
5-fluorouracil (5-FU) ointment in the treatment of benign and malignant skin lesions.
    Dermatologica, 1970, Volume: 140

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Keratoacanthoma; Keratosis; L

1970
Preliminary experience with 5-fluorouracil ointment in the treatment of neoplasias and precancerous lesions of the skin.
    Dermatologica, 1970, Volume: 140

    Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Neoplasm Metast

1970
Erythroplasia of Queyrat: repor. of a patient successfully treated with topical 5-fluorouracil.
    Canadian Medical Association journal, 1971, Jan-23, Volume: 104, Issue:2

    Topics: Adult; Drug Hypersensitivity; Erythroplasia; Fluorouracil; Humans; Male; Penile Diseases; Precancero

1971
Treatment of Bowen's disease with topical 5-fluorouracil under occlusion.
    Archives of dermatology, 1968, Volume: 97, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Fluorouracil; Humans; Precancerous Conditions; Skin Neoplasms; Thigh

1968
Topical chemotherapy of precancerous dermatoses.
    Texas medicine, 1968, Volume: 64, Issue:8

    Topics: Fluorouracil; Humans; Keratosis; Precancerous Conditions

1968
Topical 5-fluorouracil in the treatment of actinic keratoses.
    Missouri medicine, 1968, Volume: 65, Issue:12

    Topics: Aged; Fluorouracil; Humans; Keratosis; Male; Neoplasms, Radiation-Induced; Precancerous Conditions;

1968
[Experiences with a cytostaticly active ointment in the dermatologic practice. (5 per cent--5-fluorouracil ointment)].
    Wiener medizinische Wochenschrift (1946), 1969, Mar-29, Volume: 119, Issue:13

    Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Lichen P

1969
Preliminary studies in the use of 5-fluoro-uracil cream in the treatment of malignant and premalignant skin tumours.
    The Medical journal of Australia, 1969, Aug-23, Volume: 2, Issue:8

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Keratoacanthoma; Keratosis; O

1969