fluorouracil has been researched along with Concomitant Strabismus in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 7.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 7.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 3.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 3.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eşme, A | 1 |
| Yildirim, C | 1 |
| Tatlipinar, S | 1 |
| Düzcan, E | 1 |
| Yaylali, V | 1 |
| Ozden, S | 1 |
| Hwang, JM | 1 |
| Chang, BL | 1 |
| Mora, JS | 1 |
| Sprunger, DT | 1 |
| Helveston, EM | 1 |
| Evan, AP | 1 |
| Flynn, JT | 1 |
4 other studies available for fluorouracil and Concomitant Strabismus
| Article | Year |
|---|---|
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo | 2004 |
Combined effect of Interceed and 5-fluorouracil on delayed adjustable strabismus surgery.
Topics: Adaptation, Physiological; Animals; Antimetabolites; Cellulose, Oxidized; Chondroitin; Chondroitin S | 1999 |
Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery.
Topics: Administration, Topical; Animals; Antimetabolites; Cicatrix; Conjunctiva; Fluorouracil; Intraoperati | 1997 |
Problems in strabismus management.
Topics: Adolescent; Child; Cicatrix; Female; Fluorouracil; Humans; Male; Postoperative Complications; Strabi | 1986 |