fluorouracil has been researched along with Complications of Diabetes Mellitus in 14 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported a 35% overall response rate (ORR) with biweekly 5-fluorouracil (5-FU) continuous infusion (TTD [Spanish Cooperative Group for Digestive Tumour Therapy] schedule) plus irinotecan as first-line therapy in elderly patients with metastatic colorectal cancer (mCRC)." | 9.16 | Oxaliplatin in combination with infusional 5-fluorouracil as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumors. ( Alfaro, J; Aparicio, J; Aranda, E; Benavides, M; Cabrera, E; Campos, JM; Carrato, A; Dueñas, R; Etxeberría, A; Gil-Calle, S; Gómez, A; Gómez, MJ; González-Flores, E; Guasch, I; Marcuello, E; Massutí, B; Pericay, C; Queralt, B; Reina, JJ; Valladares-Ayerbes, M, 2012) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 5.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| "We previously reported a 35% overall response rate (ORR) with biweekly 5-fluorouracil (5-FU) continuous infusion (TTD [Spanish Cooperative Group for Digestive Tumour Therapy] schedule) plus irinotecan as first-line therapy in elderly patients with metastatic colorectal cancer (mCRC)." | 5.16 | Oxaliplatin in combination with infusional 5-fluorouracil as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumors. ( Alfaro, J; Aparicio, J; Aranda, E; Benavides, M; Cabrera, E; Campos, JM; Carrato, A; Dueñas, R; Etxeberría, A; Gil-Calle, S; Gómez, A; Gómez, MJ; González-Flores, E; Guasch, I; Marcuello, E; Massutí, B; Pericay, C; Queralt, B; Reina, JJ; Valladares-Ayerbes, M, 2012) |
| "Treatment with fluconazole was ineffective, but amphotericin B was curative." | 1.29 | Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole. ( Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Gao, HY | 1 |
| Baba, M | 1 |
| Okada, Y | 1 |
| Okuyama, T | 1 |
| Wu, LJ | 1 |
| Zhan, LB | 1 |
| Russolillo, N | 1 |
| Ratti, F | 1 |
| Viganò, L | 1 |
| Langella, S | 1 |
| Cipriani, F | 1 |
| Aldrighetti, L | 1 |
| Ferrero, A | 1 |
| Benavides, M | 1 |
| Pericay, C | 1 |
| Valladares-Ayerbes, M | 1 |
| Gil-Calle, S | 1 |
| Massutí, B | 1 |
| Aparicio, J | 1 |
| Dueñas, R | 1 |
| González-Flores, E | 1 |
| Carrato, A | 1 |
| Marcuello, E | 1 |
| Gómez, A | 1 |
| Cabrera, E | 1 |
| Queralt, B | 1 |
| Gómez, MJ | 1 |
| Guasch, I | 1 |
| Etxeberría, A | 1 |
| Alfaro, J | 1 |
| Campos, JM | 1 |
| Reina, JJ | 1 |
| Aranda, E | 1 |
| McNaught, A | 1 |
| Lemperle, G | 1 |
| Rullan, PP | 1 |
| Gauthier-Hazan, N | 1 |
| Vokes, EE | 1 |
| Ratain, MJ | 1 |
| Mick, R | 1 |
| McEvilly, JM | 1 |
| Haraf, D | 1 |
| Kozloff, M | 1 |
| Hamasaki, V | 1 |
| Weichselbaum, RR | 1 |
| Panje, WR | 1 |
| Wenig, B | 1 |
| Arranz-Caso, JA | 1 |
| Lopez-Pizarro, VM | 1 |
| Gomez-Herruz, P | 1 |
| García-Altozano, J | 1 |
| Martinez-Martinez, J | 1 |
| Khalil, A | 1 |
| Chammas, M | 1 |
| Shamseddine, A | 1 |
| Seoud, M | 1 |
| Sadoff, L | 1 |
| Lehmann, OJ | 1 |
| Bunce, C | 1 |
| Matheson, MM | 1 |
| Maurino, V | 1 |
| Khaw, PT | 1 |
| Wormald, R | 1 |
| Barton, K | 1 |
| Chihara, E | 1 |
| Hayashida, T | 1 |
| Yamamoto, A | 1 |
| Torii, H | 1 |
| Nakamura, A | 1 |
| Yoshida, S | 1 |
| Sawada, A | 1 |
| Pearson, LH | 1 |
| Smith, JG | 1 |
| Chalker, DK | 1 |
| Lokich, JJ | 1 |
| Skarin, AT | 1 |
| Hermann, J | 1 |
| Plenert, W | 1 |
2 reviews available for fluorouracil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Avoiding and treating dermal filler complications.
Topics: Adipose Tissue; Adrenal Cortex Hormones; Animals; Autoimmune Diseases; Biocompatible Materials; Catt | 2006 |
[Generalized candida mycoses].
Topics: Amphotericin B; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Burns; Candida albicans; Candidi | 1974 |
3 trials available for fluorouracil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Oxaliplatin in combination with infusional 5-fluorouracil as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a phase II study of the Spanish Cooperative Group for the Treatment of Digestive Tumors.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diabe | 2012 |
Cisplatin, fluorouracil, and leucovorin augmented by interferon alfa-2b in head and neck cancer: a clinical and pharmacologic analysis.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Diabetes Complic | 1993 |
Combination therapy with 5-fluorouracil (5-FU; NSC-19893) and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962) for disseminated gastrointestinal carcinoma.
Topics: Adult; Aged; Anemia, Aplastic; Blood Cell Count; Carcinoma; Clinical Trials as Topic; Colonic Neopla | 1972 |
9 other studies available for fluorouracil and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Extracts and compounds with anti-diabetic complications and anti-cancer activity from Castanea mollissina Blume (Chinese chestnut).
Topics: Aldehyde Reductase; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Diabete | 2014 |
The Influence of Aging on Hepatic Regeneration and Early Outcome after Portal Vein Occlusion: A Case-Control Study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; | 2015 |
Loss of vision after phacotrabeculectomy.
Topics: Antimetabolites; Blindness; Chemotherapy, Adjuvant; Conjunctival Diseases; Cysts; Diabetes Complicat | 2005 |
Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole.
Topics: Administration, Inhalation; Amphotericin B; Biopsy; Candidiasis; Candidiasis, Oral; Diabetes Complic | 1996 |
Fatal acute tumor lysis syndrome following treatment of vulvar carcinoma: case report.
Topics: Aged; Carcinoma, Squamous Cell; Cisplatin; Diabetes Complications; Fatal Outcome; Female; Fluorourac | 1998 |
Overwhelming 5-fluorouracil toxicity in patients whose diabetes is poorly controlled.
Topics: Aged; Antimetabolites, Antineoplastic; Diabetes Complications; Female; Fluorouracil; Humans; Hypergl | 1998 |
Risk factors for development of post-trabeculectomy endophthalmitis.
Topics: Aged; Antimetabolites; Case-Control Studies; Diabetes Complications; Endophthalmitis; Female; Fluoro | 2000 |
[Treatment of neovascular glaucoma by seton and 5-FU].
Topics: Combined Modality Therapy; Diabetes Complications; Fluorouracil; Glaucoma; Humans; Male; Methods; Mi | 1987 |
Hyperkeratosis lenticularis perstans (Flegel's disease). Case report and literature review.
Topics: Administration, Cutaneous; Diabetes Complications; Fluorouracil; Humans; Keratosis; Male; Middle Age | 1987 |