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fluorouracil and Complex Partial Epilepsy

fluorouracil has been researched along with Complex Partial Epilepsy in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weh, HJ1
Bittner, S1
Hoffknecht, M1
Hossfeld, DK1

Other Studies

1 other study available for fluorouracil and Complex Partial Epilepsy

ArticleYear
Neurotoxicity following weekly therapy with folinic acid and high-dose 5-fluorouracil 24-h infusion in patients with gastrointestinal malignancies.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Epilepsy, Complex Partial; Female

1993