fluorouracil has been researched along with Colitis Gravis in 14 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present an additional case of rectal squamous cell carcinoma (SCC) complicating chronic ulcerative colitis in a 33-year-old woman who had the disease for 15 years." | 2.39 | Squamous cell carcinoma complicating idiopathic inflammatory bowel disease. ( Butler, B; Doerr, R; Kulaylat, MN; Satchidanand, SK; Singh, A, 1995) |
| "Anal squamous cell carcinoma has rarely been reported in the setting of ulcerative colitis." | 1.62 | Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols? ( Click, B; Hull, TL; Lightner, AL; McMichael, J; Regueiro, M; Steele, SR; Vaidya, P, 2021) |
| "Eighteen cases of stage IV CAC (7 ulcerative colitis, 11 Crohn disease) and 18 CRC were identified." | 1.56 | Systemic Chemotherapy for Metastatic Colitis-Associated Cancer Has a Worse Outcome Than Sporadic Colorectal Cancer: Matched Case Cohort Analysis. ( Bates, DDB; Capanu, M; Chatila, W; Chou, J; Hersch, J; Kelsen, D; Paroder, V; Schultz, N; Tang, L; Yaeger, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (50.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, W | 1 |
| Ren, D | 1 |
| Shao, H | 1 |
| Zhang, X | 1 |
| Li, T | 1 |
| Zhang, L | 1 |
| Liu, L | 1 |
| Zhao, Y | 1 |
| Niu, P | 1 |
| Yang, X | 1 |
| Yaeger, R | 1 |
| Paroder, V | 1 |
| Bates, DDB | 1 |
| Capanu, M | 1 |
| Chou, J | 1 |
| Tang, L | 1 |
| Chatila, W | 1 |
| Schultz, N | 1 |
| Hersch, J | 1 |
| Kelsen, D | 1 |
| Lightner, AL | 1 |
| Vaidya, P | 1 |
| McMichael, J | 1 |
| Click, B | 1 |
| Regueiro, M | 1 |
| Steele, SR | 1 |
| Hull, TL | 1 |
| Chen, Y | 1 |
| Schaeffer, DF | 1 |
| Yoshida, EM | 1 |
| Iseki, Y | 1 |
| Maeda, K | 1 |
| Shibutani, M | 1 |
| Nagahara, H | 1 |
| Ikeya, T | 1 |
| Tamura, T | 1 |
| Ohira, G | 1 |
| Sakurai, K | 1 |
| Yamazoe, S | 1 |
| Kimura, K | 1 |
| Toyokawa, T | 1 |
| Kubo, N | 1 |
| Tanaka, H | 1 |
| Muguruma, K | 1 |
| Hirakawa, K | 1 |
| GOLDGRABER, MB | 1 |
| KIRSNER, JB | 2 |
| Kulaylat, MN | 1 |
| Doerr, R | 1 |
| Butler, B | 1 |
| Satchidanand, SK | 1 |
| Singh, A | 1 |
| Welch, CE | 1 |
| Levin, B | 1 |
| Karlin, DA | 1 |
| Schulman, S | 1 |
| Thorp, GW | 1 |
| Rosenberg, IH | 1 |
| Brinkmann, J | 1 |
| Breier, B | 1 |
| Goos, M | 1 |
| Gear, EV | 1 |
| Kaufmann, HJ | 1 |
| Spiro, HM | 1 |
| Floch, MH | 1 |
| Donaldson, GA | 1 |
| Welch, JP | 1 |
| Barrett, O | 1 |
| Bourgeois, C | 1 |
| Plecha, FR | 1 |
4 reviews available for fluorouracil and Colitis Gravis
| Article | Year |
|---|---|
Squamous cell carcinoma complicating idiopathic inflammatory bowel disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Carcinoma, Transiti | 1995 |
Abdominal surgery (second of three parts).
Topics: Abdomen; Acute Disease; Anus Diseases; Appendectomy; Appendicitis; Appendix; Carcinoembryonic Antige | 1975 |
Dobbins WO 3d,+DOBBINS WO III: Rectal biopsy. A review of its diagnostic usefulness.
Topics: Amyloidosis; Biopsy; Colitis, Ulcerative; Crohn Disease; Cystic Fibrosis; Cysts; Deficiency Diseases | 1968 |
Management of cancer of the colon.
Topics: Colitis, Ulcerative; Colon; Colonic Diseases; Colonic Neoplasms; Diagnostic Errors; Fluorouracil; Hu | 1974 |
10 other studies available for fluorouracil and Colitis Gravis
| Article | Year |
|---|---|
Theabrownin from Fu Brick Tea Improves Ulcerative Colitis by Shaping the Gut Microbiota and Modulating the Tryptophan Metabolism.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Fluorouracil; | 2023 |
Systemic Chemotherapy for Metastatic Colitis-Associated Cancer Has a Worse Outcome Than Sporadic Colorectal Cancer: Matched Case Cohort Analysis.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Case-C | 2020 |
Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel | 2021 |
Hepatoid adenocarcinoma of the colon in a patient with inflammatory bowel disease.
Topics: Adenocarcinoma; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; B | 2014 |
[A Patient with Recurrent Ulcerative Colitis-Associated Rectal Cancer Attaining a Complete Response with FOLFIRI plus Bevacizumab].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colitis, Ulcerative; Comb | 2015 |
CARCINOMA OF THE COLON IN ULCERATIVE COLITIS.
Topics: Aged; Aging; Cell Biology; Colitis; Colitis, Ulcerative; Colonic Neoplasms; Fluorouracil; Humans; Me | 1964 |
The gasteointestinal oncology clinic. A multidisciplinary approach to cancer diagnosis and management at a University Medical Center.
Topics: Adenocarcinoma; Colitis, Ulcerative; Colonic Neoplasms; Cyclophosphamide; Drug Therapy, Combination; | 1976 |
[Hypertrichosis lanuginosa acquisita in ulcerative colitis with colon cancer].
Topics: Adenocarcinoma; Adult; Biopsy; Cecal Neoplasms; Chemotherapy, Adjuvant; Colectomy; Colitis, Ulcerati | 1992 |
Intestinal epithelial enzyme abnormalities induced by 5-fluorouracil: translocation of NADPH2-dehydrogenase.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Autopsy; Biopsy; Colitis, Ulcerative; Colon; Estera | 1967 |
Fluorouracil toxicity following gastrointestinal surgery.
Topics: Adenocarcinoma; Colitis, Ulcerative; Colostomy; Fluorouracil; Humans; Intestinal Mucosa; Intestinal | 1965 |