Page last updated: 2024-10-27

fluorouracil and Colitis, Ischemic

fluorouracil has been researched along with Colitis, Ischemic in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Colitis, Ischemic: Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.

Research Excerpts

ExcerptRelevanceReference
"An endoscopy showed a mild, transient ischemic colitis."1.37Ischemic colitis after capecitabine plus cisplatin treatment in advanced gastric cancer. ( Benekli, M; Buyukberber, S; Cetin, B; Coskun, U; Güzel, E; Sentürk, S, 2011)
"Especially ischemic colitis can rapidly develop into bowel perforation, so an emergency operation often is needed."1.37[A case of severe bevacizumab-induced ischemic pancolitis, treated with conservative management]. ( Chun, SH; Kim, SW; Lee, H; Lee, HM; Lee, HN; Lee, MA; Lim, Y; Won, HS, 2011)
"Gastrointestinal perforation is a known risk factor of unknown etiology associated with the use of bevacizumab."1.35[Ischemic anastomotic bowel perforation during treatment with bevacizumab 10 months after surgery]. ( Abbrederis, K; Kremer, M; Schuhmacher, C, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cetin, B1
Buyukberber, S1
Sentürk, S1
Güzel, E1
Coskun, U1
Benekli, M1
Lee, HN1
Lee, MA1
Kim, SW1
Lim, Y1
Lee, H1
Lee, HM1
Won, HS1
Chun, SH1
Abbrederis, K1
Kremer, M1
Schuhmacher, C1
Paran, H1
Edelstein, E1
Klein, B1
Gutman, M1

Other Studies

4 other studies available for fluorouracil and Colitis, Ischemic

ArticleYear
Ischemic colitis after capecitabine plus cisplatin treatment in advanced gastric cancer.
    Journal of thrombosis and thrombolysis, 2011, Volume: 31, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Colitis, Ischemic; Deoxycyt

2011
[A case of severe bevacizumab-induced ischemic pancolitis, treated with conservative management].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Volume: 58, Issue:1

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2011
[Ischemic anastomotic bowel perforation during treatment with bevacizumab 10 months after surgery].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2008, Volume: 79, Issue:4

    Topics: Anastomosis, Surgical; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Huma

2008
Extensive colonic ischemia following treatment with bevacizumab, fluouracil and CPT-11 in a young patient with advanced adenocarcinoma of the rectum.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Huma

2007