fluorouracil has been researched along with Colicky Pain in 27 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholinergic syndrome is an acute adverse reaction associated with irinotecan." | 7.88 | Predictive factors for the development of irinotecan-related cholinergic syndrome using ordered logistic regression analysis. ( Hosokawa, T; Ishikawa, T; Kanazawa, M; Kanbayashi, Y; Kawano, R; Nakajima, Y; Tabuchi, Y; Taguchi, T; Takayama, K; Yoshida, N; Yoshioka, T, 2018) |
| " Patients exhibited high compliance in dosing administration." | 6.74 | Phase II, randomized, double-blind, placebo-controlled study of recombinant human intestinal trefoil factor oral spray for prevention of oral mucositis in patients with colorectal cancer who are receiving fluorouracil-based chemotherapy. ( Akhmadullina, LI; Barker, NP; Davidenko, IS; Firsov, I; Gertner, JM; Gotovkin, EA; Kopp, MV; Kulikov, EP; Moiseyenko, VM; Peterson, DE; Rakovskaya, GN; Rodionova, I; Sherman, NZ; Shinkarev, SA; Tuleneva, T; Woon, CW; Yarosh, A, 2009) |
| "Gemcitabine (dFdC) is a prodrug that undergoes metabolism by cytidine deaminase to form an inactive metabolite, 2',2'-difluorodeoxyuridine (dFdU)." | 5.31 | Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites. ( Delauter, BJ; Egorin, MJ; Plunkett, W; Ramanathan, RK; Stover, LL; Zamboni, WC; Zuhowski, EG, 2000) |
| "Cholinergic syndrome is an acute adverse reaction associated with irinotecan." | 3.88 | Predictive factors for the development of irinotecan-related cholinergic syndrome using ordered logistic regression analysis. ( Hosokawa, T; Ishikawa, T; Kanazawa, M; Kanbayashi, Y; Kawano, R; Nakajima, Y; Tabuchi, Y; Taguchi, T; Takayama, K; Yoshida, N; Yoshioka, T, 2018) |
| "For patients with incurable stage IV colorectal cancer, minimally symptomatic primary tumours were left in situ and 5-fluorouracil-based chemotherapy was administered systemically." | 3.71 | Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer. ( Guillou, PJ; Guthrie, JA; O'Riordain, DS; Ride, E; Sarela, AI; Seymour, MT, 2001) |
| " Patients exhibited high compliance in dosing administration." | 2.74 | Phase II, randomized, double-blind, placebo-controlled study of recombinant human intestinal trefoil factor oral spray for prevention of oral mucositis in patients with colorectal cancer who are receiving fluorouracil-based chemotherapy. ( Akhmadullina, LI; Barker, NP; Davidenko, IS; Firsov, I; Gertner, JM; Gotovkin, EA; Kopp, MV; Kulikov, EP; Moiseyenko, VM; Peterson, DE; Rakovskaya, GN; Rodionova, I; Sherman, NZ; Shinkarev, SA; Tuleneva, T; Woon, CW; Yarosh, A, 2009) |
| "To evaluate the association of age with treatment-related adverse events and survival in patients with mCRC and explore the potential underlying factors." | 1.91 | Association of Age With Treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal Cancer. ( Delgado, MG; Gomez, MF; Hubbard, JM; Ji, R; Kim, RD; Knepper, TC; Laber, DA; Meng, L; Permuth, JB; Thapa, R; Wang, X; Xie, H, 2023) |
| "Thus, pancreatic cancer of the tail often presents late with a very poor prognosis." | 1.51 | The seemingly innocuous presentation of metastatic pancreatic tail cancer: a case report. ( Rahman, M; Washington, L, 2019) |
| "The authors conclude that multiple synchronous neoplasms can be treated with individualized chemotherapeutic protocol with good efficacy and few adverse reactions." | 1.42 | [Individualized therapy of synchronous ovarian and colon cancers with lymph]. ( Bishr, AM; Deme, D; Nizar, J; Telekes, A, 2015) |
| "Abdominal pain was the most frequent symptom (36." | 1.40 | Retrospective analysis of 119 small bowel adenocarcinoma in Chinese patients. ( Bai, L; Guo, XC; Mao, ZY; Su, D; Wang, LJ; Zhang, TT, 2014) |
| "Computed tomography showed intussusception caused by a large tumor in the pelvis and absence of distant metastases." | 1.40 | Intussusception due to rectal adenocarcinoma in a young adult: a case report. ( Fujiwara, T; Inada, R; Kishimoto, H; Kondo, Y; Mori, Y; Nagasaka, T; Toshima, T, 2014) |
| "Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin." | 1.31 | Squamous cell carcinoma of the pancreas with cystic degeneration. ( Colarian, J; Fowler, D; Poolos, S; Schor, J, 2000) |
| "Gemcitabine (dFdC) is a prodrug that undergoes metabolism by cytidine deaminase to form an inactive metabolite, 2',2'-difluorodeoxyuridine (dFdU)." | 1.31 | Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites. ( Delauter, BJ; Egorin, MJ; Plunkett, W; Ramanathan, RK; Stover, LL; Zamboni, WC; Zuhowski, EG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 11 (40.74) | 24.3611 |
| 2020's | 4 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Meng, L | 1 |
| Thapa, R | 1 |
| Delgado, MG | 1 |
| Gomez, MF | 1 |
| Ji, R | 1 |
| Knepper, TC | 1 |
| Hubbard, JM | 1 |
| Wang, X | 1 |
| Permuth, JB | 1 |
| Kim, RD | 1 |
| Laber, DA | 1 |
| Xie, H | 1 |
| Loi, M | 1 |
| Magallon-Baro, A | 1 |
| Suker, M | 1 |
| Van Eijck, C | 1 |
| Hoogeman, M | 1 |
| Nuyttens, JJ | 1 |
| Kanbayashi, Y | 1 |
| Ishikawa, T | 1 |
| Kanazawa, M | 1 |
| Nakajima, Y | 1 |
| Tabuchi, Y | 1 |
| Kawano, R | 1 |
| Yoshioka, T | 1 |
| Yoshida, N | 1 |
| Hosokawa, T | 1 |
| Takayama, K | 1 |
| Taguchi, T | 1 |
| Kao, CT | 1 |
| Aziz, M | 1 |
| Kasi, A | 1 |
| Paula, DP | 1 |
| do Brasil Costa, VI | 1 |
| Jorge, RV | 1 |
| Nobre, FF | 1 |
| Rahman, M | 1 |
| Washington, L | 1 |
| Yasuda, T | 1 |
| Tanaka, O | 1 |
| Hayashi, S | 1 |
| Nakahata, Y | 1 |
| Yasuda, Y | 1 |
| Omatsu, T | 1 |
| Obora, A | 1 |
| Kojima, T | 1 |
| Matsuo, M | 1 |
| Yagi, N | 1 |
| Ryan, EM | 1 |
| Hanly, A | 1 |
| Morrin, MM | 1 |
| McNamara, DA | 1 |
| Guo, XC | 1 |
| Mao, ZY | 1 |
| Su, D | 1 |
| Wang, LJ | 1 |
| Zhang, TT | 1 |
| Bai, L | 1 |
| Inada, R | 1 |
| Nagasaka, T | 1 |
| Toshima, T | 1 |
| Mori, Y | 1 |
| Kondo, Y | 1 |
| Kishimoto, H | 1 |
| Fujiwara, T | 1 |
| Deme, D | 1 |
| Bishr, AM | 1 |
| Nizar, J | 1 |
| Telekes, A | 1 |
| Lee, J | 1 |
| Axilbund, J | 1 |
| Dalton, WB | 1 |
| Laheru, D | 1 |
| Watkins, S | 1 |
| Chu, D | 1 |
| Cravero, K | 1 |
| Button, B | 1 |
| Kyker-Snowman, K | 1 |
| Waters, I | 1 |
| Gocke, CD | 1 |
| Lauring, J | 1 |
| Park, BH | 1 |
| Peterson, DE | 1 |
| Barker, NP | 1 |
| Akhmadullina, LI | 1 |
| Rodionova, I | 1 |
| Sherman, NZ | 1 |
| Davidenko, IS | 1 |
| Rakovskaya, GN | 1 |
| Gotovkin, EA | 1 |
| Shinkarev, SA | 1 |
| Kopp, MV | 1 |
| Kulikov, EP | 1 |
| Moiseyenko, VM | 1 |
| Gertner, JM | 1 |
| Firsov, I | 1 |
| Tuleneva, T | 1 |
| Yarosh, A | 1 |
| Woon, CW | 1 |
| Mastoraki, A | 1 |
| Papanikolaou, IS | 1 |
| Kanakis, D | 1 |
| Safioleas, P | 1 |
| Sakorafas, G | 1 |
| Safioleas, M | 1 |
| Sargen, M | 1 |
| Wanat, KA | 1 |
| Jambusaria, A | 1 |
| Rosenbach, M | 1 |
| Sobanko, J | 1 |
| Miller, CJ | 1 |
| Peddi, PF | 1 |
| Lubner, S | 1 |
| McWilliams, R | 1 |
| Tan, BR | 1 |
| Picus, J | 1 |
| Sorscher, SM | 1 |
| Suresh, R | 1 |
| Lockhart, AC | 1 |
| Wang, J | 1 |
| Menias, C | 1 |
| Gao, F | 1 |
| Linehan, D | 1 |
| Wang-Gillam, A | 1 |
| Takahashi, K | 1 |
| Mori, T | 1 |
| Ohue, M | 1 |
| Yamaguchi, T | 2 |
| Blanke, CD | 2 |
| Mattek, NC | 1 |
| Deloughery, TG | 1 |
| Koop, DR | 1 |
| Kawakami, H | 1 |
| Uno, T | 1 |
| Isobe, K | 1 |
| Ueno, N | 1 |
| Aruga, T | 1 |
| Sudo, K | 1 |
| Saisho, H | 1 |
| Kawata, T | 1 |
| Ito, H | 1 |
| Sugihara, K | 1 |
| Sanz-Altamira, PM | 1 |
| Spence, LD | 1 |
| Huberman, MS | 1 |
| Posner, MR | 1 |
| Steele, G | 1 |
| Perry, LJ | 1 |
| Stuart, KE | 1 |
| Fujii, K | 1 |
| Nakashima, K | 1 |
| Ohno, T | 1 |
| Anai, H | 1 |
| Ukarapol, N | 1 |
| Wongsawasdi, L | 1 |
| Singhavejsakul, J | 1 |
| Colarian, J | 1 |
| Fowler, D | 1 |
| Schor, J | 1 |
| Poolos, S | 1 |
| Delauter, BJ | 1 |
| Ramanathan, RK | 1 |
| Egorin, MJ | 1 |
| Stover, LL | 1 |
| Zuhowski, EG | 1 |
| Plunkett, W | 1 |
| Zamboni, WC | 1 |
| Stipanov, M | 1 |
| Morrow, J | 1 |
| Rothenberg, M | 1 |
| Chinery, R | 1 |
| Shyr, Y | 1 |
| Coffey, R | 1 |
| Johnson, DH | 1 |
| Leach, SD | 1 |
| Beauchamp, RD | 1 |
| Sarela, AI | 1 |
| Guthrie, JA | 1 |
| Seymour, MT | 1 |
| Ride, E | 1 |
| Guillou, PJ | 1 |
| O'Riordain, DS | 1 |
2 reviews available for fluorouracil and Colicky Pain
| Article | Year |
|---|---|
Systemic toxicity from occlusive therapy with topical 5-fluorouracil: a case report and review of the literature.
Topics: Abdominal Pain; Administration, Cutaneous; Antimetabolites, Antineoplastic; Chills; Diarrhea; Drug E | 2012 |
Colonic carcinoma: a case report in a child and review literature.
Topics: Abdominal Pain; Adenocarcinoma; Biopsy, Needle; Child; Colectomy; Colonic Neoplasms; Fluorouracil; F | 2000 |
8 trials available for fluorouracil and Colicky Pain
| Article | Year |
|---|---|
Daily dose to organs at risk predicts acute toxicity in pancreatic stereotactic radiotherapy.
Topics: Abdominal Pain; Acute Disease; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; | 2020 |
Phase II, randomized, double-blind, placebo-controlled study of recombinant human intestinal trefoil factor oral spray for prevention of oral mucositis in patients with colorectal cancer who are receiving fluorouracil-based chemotherapy.
Topics: Abdominal Pain; Aged; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Diarrhea | 2009 |
Multi-institutional experience with FOLFIRINOX in pancreatic adenocarcinoma.
Topics: Abdominal Pain; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptot | 2012 |
A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer.
Topics: Abdominal Pain; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Colorectal Neoplasms; Cyc | 2005 |
Continuous hepatic arterial infusion of 5-fluorouracil for unresectable colorectal liver metastases: phase II study.
Topics: Abdominal Pain; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Follow-Up Stu | 1995 |
Selective chemoembolization in the management of hepatic metastases in refractory colorectal carcinoma: a phase II trial.
Topics: Abdominal Pain; Adult; Aged; Alkaline Phosphatase; Angiography; Antimetabolites, Antineoplastic; Ant | 1997 |
[Evaluation of 5-fluorouracil concentration in peripheral blood and side effects in continuous hepatic arterial infusion chemotherapy for patients with unresectable liver cancer].
Topics: Abdominal Pain; Aged; Anorexia; Antimetabolites, Antineoplastic; Drug Administration Schedule; Femal | 1997 |
A phase I study of vitamin E, 5-fluorouracil and leucovorin for advanced malignancies.
Topics: Abdominal Pain; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Dinoprost; Do | 2001 |
17 other studies available for fluorouracil and Colicky Pain
| Article | Year |
|---|---|
Association of Age With Treatment-Related Adverse Events and Survival in Patients With Metastatic Colorectal Cancer.
Topics: Abdominal Pain; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Female; Fluorouracil; Human | 2023 |
Predictive factors for the development of irinotecan-related cholinergic syndrome using ordered logistic regression analysis.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bloo | 2018 |
Pathological complete response in pancreatic adenocarcinoma with FOLFIRINOX.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th | 2018 |
Impact of protocol change on individual factors related to course of adverse reactions to chemotherapy for breast cancer.
Topics: Abdominal Pain; Adult; Aged; Alcohol Oxidoreductases; Antineoplastic Combined Chemotherapy Protocols | 2020 |
The seemingly innocuous presentation of metastatic pancreatic tail cancer: a case report.
Topics: Abdominal Pain; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Diabe | 2019 |
Successful treatment of unresectable advanced rectal cancer with liver metastases by hemostasis re-irradiation of the rectal cancer and palliative low-dose whole-liver radiation therapy: a case report.
Topics: Abdominal Pain; Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothe | 2020 |
Unusual ischemic complication of bevacizumab treatment for metastatic colorectal carcinoma.
Topics: Abdominal Pain; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Co | 2013 |
Retrospective analysis of 119 small bowel adenocarcinoma in Chinese patients.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Cap | 2014 |
Intussusception due to rectal adenocarcinoma in a young adult: a case report.
Topics: Abdominal Pain; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; B | 2014 |
[Individualized therapy of synchronous ovarian and colon cancers with lymph].
Topics: Abdominal Pain; Adenocarcinoma; Adenocarcinoma, Papillary; Aged; Antineoplastic Agents, Phytogenic; | 2015 |
A Polycythemia Vera JAK2 Mutation Masquerading as a Duodenal Cancer Mutation.
Topics: Abdominal Pain; Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; C | 2016 |
A case of signet ring carcinoma of the appendix: dilemmas in differential diagnosis and management.
Topics: Abdominal Pain; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Appendiceal Neoplasms; | 2010 |
[The prevention of negative side effects in homeochemotherapy].
Topics: Abdominal Pain; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neop | 2002 |
Toxicities and effects of involved-field irradiation with concurrent cisplatin for unresectable carcinoma of the pancreas.
Topics: Abdominal Pain; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Back Pa | 2005 |
Squamous cell carcinoma of the pancreas with cystic degeneration.
Topics: Abdominal Pain; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Squamou | 2000 |
Pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in a patient with ascites.
Topics: Abdominal Pain; Adenocarcinoma; Antimetabolites, Antineoplastic; Ascites; Catheters, Indwelling; Chr | 2000 |
Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer.
Topics: Abdominal Pain; Adult; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neop | 2001 |