Page last updated: 2024-10-27

fluorouracil and Coccidioidomycosis

fluorouracil has been researched along with Coccidioidomycosis in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Coccidioidomycosis: Infection with a fungus of the genus COCCIDIOIDES, endemic to the SOUTHWESTERN UNITED STATES. It is sometimes called valley fever but should not be confused with RIFT VALLEY FEVER. Infection is caused by inhalation of airborne, fungal particles known as arthroconidia, a form of FUNGAL SPORES. A primary form is an acute, benign, self-limited respiratory infection. A secondary form is a virulent, severe, chronic, progressive granulomatous disease with systemic involvement. It can be detected by use of COCCIDIOIDIN.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takeda, K1
Oritsu, M1
Sakuta, M1
Busey, JF1

Reviews

1 review available for fluorouracil and Coccidioidomycosis

ArticleYear
Modern concepts in the diagnosis and management of the pulmonary mycoses.
    Clinical notes on respiratory diseases, 1976,Spring, Volume: 14, Issue:4

    Topics: Amphotericin B; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Complement Fixation T

1976

Other Studies

1 other study available for fluorouracil and Coccidioidomycosis

ArticleYear
[A case of coccidioidomycosis with central nervous system involvement].
    Rinsho shinkeigaku = Clinical neurology, 1993, Volume: 33, Issue:11

    Topics: Adult; Chronic Disease; Coccidioides; Coccidioidomycosis; Fluorouracil; Humans; Hydrocephalus; Male;

1993