Page last updated: 2024-10-27

fluorouracil and Clostridium Infections

fluorouracil has been researched along with Clostridium Infections in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Clostridium Infections: Infections with bacteria of the genus CLOSTRIDIUM and closely related CLOSTRIDIOIDES species.

Research Excerpts

ExcerptRelevanceReference
"We present a patient with metastatic breast cancer treated with high-dose chemotherapy and bone marrow transplantation."1.29Clostridium septicum abscess in hepatic metastases: successful medical management. ( Ciaccia, D; Corey, GR; Peters, W; Thel, MC; Vredenburgh, JJ, 1994)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thel, MC1
Ciaccia, D1
Vredenburgh, JJ1
Peters, W1
Corey, GR1
Sweeney, T1
Rieger, N1
Mackay, J1

Other Studies

2 other studies available for fluorouracil and Clostridium Infections

ArticleYear
Clostridium septicum abscess in hepatic metastases: successful medical management.
    Bone marrow transplantation, 1994, Volume: 13, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms

1994
Neutropenic proctosigmoiditis complicating breast cancer chemotherapy.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clostridium Infections;

1999