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fluorouracil and Circulatory Collapse

fluorouracil has been researched along with Circulatory Collapse in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
" In December 2004, paclitaxel and trastuzumab combination therapy was tried, but she went into shock just during administration of paclitaxel, and this therapy was discontinued."7.76[A case of HER2 overexpressing advanced breast cancer with CTF therapy [cyclophosphamide, pirarubicin (THPADM), fluorouracil] showed long-term effectiveness after paclitaxel shock]. ( Fujii, S; Ikeda, M; Kurebayashi, J; Miyake, A; Nakashima, K; Nomura, T; Oota, Y; Seki, M; Shiiki, S; Shimo, T; Sonoo, H; Tanaka, K; Yamamoto, Y, 2010)
"During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure."3.91Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019)
" In December 2004, paclitaxel and trastuzumab combination therapy was tried, but she went into shock just during administration of paclitaxel, and this therapy was discontinued."3.76[A case of HER2 overexpressing advanced breast cancer with CTF therapy [cyclophosphamide, pirarubicin (THPADM), fluorouracil] showed long-term effectiveness after paclitaxel shock]. ( Fujii, S; Ikeda, M; Kurebayashi, J; Miyake, A; Nakashima, K; Nomura, T; Oota, Y; Seki, M; Shiiki, S; Shimo, T; Sonoo, H; Tanaka, K; Yamamoto, Y, 2010)
"Patients with malignancy may present with acute circulatory compromise requiring ICU monitoring and care."2.41Circulatory shock. ( Bogolioubov, A; Groeger, JS; Keefe, DL, 2001)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giuliani, A1
Romanzi, F1
Di Sibio, A1
Calvisi, G1
Lombardi, L1
Marchese, M1
Di Staso, M1
Schietroma, M1
Carlei, F1
Romano, L1
Ikeda, M1
Sonoo, H1
Oota, Y1
Fujii, S1
Shimo, T1
Miyake, A1
Seki, M1
Nomura, T1
Yamamoto, Y1
Shiiki, S1
Nakashima, K1
Tanaka, K1
Kurebayashi, J1
Bogolioubov, A1
Keefe, DL1
Groeger, JS1
Classen, JN1
Martin, RE1
Sabagal, J1

Reviews

2 reviews available for fluorouracil and Circulatory Collapse

ArticleYear
Circulatory shock.
    Critical care clinics, 2001, Volume: 17, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Anthracyclines; Antineoplastic Agents; Carcinoid Tu

2001
Iatrogenic lesions of the colon and rectum.
    Southern medical journal, 1975, Volume: 68, Issue:11

    Topics: Adult; Aged; Angiography; Barium Sulfate; Cathartics; Colon; Colonic Diseases; Cyclophosphamide; Ele

1975

Other Studies

2 other studies available for fluorouracil and Circulatory Collapse

ArticleYear
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
    Annali italiani di chirurgia, 2019, Jun-26, Volume: 8

    Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si

2019
[A case of HER2 overexpressing advanced breast cancer with CTF therapy [cyclophosphamide, pirarubicin (THPADM), fluorouracil] showed long-term effectiveness after paclitaxel shock].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:13

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineopl

2010