fluorouracil has been researched along with Cicatrix in 72 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Cicatrix: The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 8.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "The objective of this review is to assess the effects of post-operative injections of 5-Fluorouracil in eyes of people undergoing surgery for glaucoma." | 8.81 | Post-operative 5-Fluorouracil for glaucoma surgery. ( Bunce, C; Wilkins, MR; Wormald, R, 2001) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 7.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 7.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 7.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 7.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 7.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| "Four cases of cicatricial ectropion secondary to prolonged systemic administration of 5-fluorouracil are described." | 7.65 | Cicatricial ectropion secondary to 5-fluorouracil therapy. ( Ellerby, RA; Mausolf, FA; McCracken, JD; Straus, DJ, 1977) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 6.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 6.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 5.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| "We conducted a prospective, randomized study to compare mitomycin with fluorouracil for efficacy and safety as an adjunct to trabeculectomy in eyes with glaucoma with poor surgical prognosis." | 5.07 | Trabeculectomy with mitomycin. A comparative study with fluorouracil. ( Kawase, K; Kitazawa, Y; Matsushita, H; Minobe, M, 1991) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 4.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "The objective of this review is to assess the effects of post-operative injections of 5-Fluorouracil in eyes of people undergoing surgery for glaucoma." | 4.81 | Post-operative 5-Fluorouracil for glaucoma surgery. ( Bunce, C; Wilkins, MR; Wormald, R, 2001) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 3.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "to investigate the ability of drug-loaded N,O-carboxymethyl chitosan (CMCS) hydrogels to modulate wound healing after glaucoma filtration surgery." | 3.76 | Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation. ( CAI, X; CHEN, RF; CHENG, LZ; FAN, JZ; GUO, H; LAN, YQ; YANG, LQ; ZHANG, LM; ZHOU, HS, 2010) |
| "To investigate the influence of 5-fluorouracil (5-FU) and mitomycin C (MMC) on the postoperative adhesions following strabismus surgery in rabbits." | 3.72 | Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits. ( Düzcan, E; Eşme, A; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004) |
| "To determine whether 5-fluorouracil is effective in reducing scarring after strabismus surgery we used rectus muscle surgery in experimental animals to compare a single intraoperative dose of 5-fluorouracil with mitomycin C and to compare results in similarly treated controls not receiving these antimetabolites." | 3.69 | Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery. ( Evan, AP; Helveston, EM; Mora, JS; Sprunger, DT, 1997) |
| "Repeated doses of 5mg of 5-fluorouracil (5-FU) were injected subconjunctivally in 25 poor-prognosis glaucomatous eyes after filtering surgery to prevent filtering bleb scarring." | 3.68 | Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring. ( Ophir, A; Ticho, U, 1991) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 3.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 3.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| "Four cases of cicatricial ectropion secondary to prolonged systemic administration of 5-fluorouracil are described." | 3.65 | Cicatricial ectropion secondary to 5-fluorouracil therapy. ( Ellerby, RA; Mausolf, FA; McCracken, JD; Straus, DJ, 1977) |
| "The oral mucositis is a mucosal alteration that usually arises from oncological treatments, such as chemotherapy, and it is characterized as an inflammatory process." | 3.30 | The chromatographic constitution of andiroba oil and his healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option. ( Alcantara, DDFA; Burbano, RMR; Gomes, JT; Júnior, SMA; Oliveira, CP; Rodrigues, EM; Soares, BM; Soares, RHFC; Tuji, FM; Wanzeler, AMV, 2023) |
| "Hypertrophic scars and keloids may complicate wound healing secondary to trauma or surgery." | 2.69 | Treatment of inflamed hypertrophic scars using intralesional 5-FU. ( Fitzpatrick, RE, 1999) |
| "An approach to scar management that targets specific characteristics of a scar using a combination of surgical and nonsurgical modalities can significantly improve the appearance of most scars." | 2.55 | Treating Scars of the Cheek Region. ( Boahene, KD; Owusu, JA, 2017) |
| "Periorbital scarring with eyelid retraction can have serious visual effects and can lead to loss of vision or even loss of the eye." | 2.55 | Periorbital Scar Correction. ( Chambers, CB; Moe, KS, 2017) |
| "New modalities such as the scar team approach, autologous fat transfer, and ablative fractional laser resurfacing suggest a promising future for children who suffer symptomatically from their scars." | 2.53 | Scar Management in the Pediatric and Adolescent Populations. ( Donelan, MB; Krakowski, AC; Shumaker, PR; Totri, CR, 2016) |
| "Surgical scars are best treated with a combination approach to address various features of the scar." | 2.53 | A Combination Approach to Surgical Scars. ( Cohen, JL; Eilers, RE; Ortiz, AE; Ross, EV, 2016) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 2.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Though both forms of pathologic scarring are distinct entities at the macro and microscopic level, their etiologies and treatment are often similar." | 2.46 | The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review. ( Basdag, B; Magarakis, M; Manson, PN; Rosson, GD; Shridharani, SM; Singh, NK, 2010) |
| "For atrophic scars, different types of lasers represent modern treatment modalities with satisfactory results." | 2.42 | Novel opportunities in the treatment and prevention of scarring. ( Berman, B; Ramirez, CC; Villa, AM, 2004) |
| "The use of antiscarring agents, particularly the antimetabolites 5-fluorouracil and mitomycin C, have revolutionized glaucoma surgery over the past decade." | 2.39 | Current techniques in wound healing modulation in glaucoma surgery. ( Khaw, PT; Migdal, CS, 1996) |
| "The implantation of cervical cancer in an episiotomy scar is very rare." | 2.38 | Squamous cell carcinoma of the cervix implanting in the episiotomy site. ( Issa, PY; Khalil, AM; Khatib, RA; Mufarrij, AA; Tawil, AN, 1993) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 2.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "Filtering bleb encapsulation may, in some cases, be a severe complication following filtering surgery." | 2.38 | Encapsulated filtering bleb. A selective review--new deductions. ( Ophir, A, 1992) |
| "The area and the height of the bleb in the conjunctivae with radial incision (Ain and Hin, respectively) were compared with the area and the height of the bleb in the conjunctivae without radial incision (Ano and Hno, respectively)." | 1.35 | Restricted post-trabeculectomy bleb formation by conjunctival scarring. ( Inatani, M; Iwao, K; Ogata-Iwao, M; Takihara, Y; Tanihara, H, 2009) |
| "To study the effect of tissue plasminogen activator (t-PA) in combination with 5-fluorouracil (5-Fu) polyphase liposome on the prevention of scar formation in filtration surgery." | 1.30 | [The inhibitory effect of tissue plasminogen activator combined with 5-fluorouracil polyphase liposome on the scar formation in experimental filtration surgery]. ( Chen, R; Jing, M; Xi, S, 1997) |
| "A review of 20 patients with postburn scar carcinoma is presented." | 1.28 | Postburn scar carcinoma. ( Aron, NK; Tajuri, S, 1989) |
| " In addition, toxic effects of 5-FU on existing fibroblasts, in rabbits and in vitro, were demonstrated." | 1.28 | Toxic effects of 5-fluorouracil on fibroblasts following trabeculectomy. ( Ophir, A; Ticho, U, 1992) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 1.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| "Ater eight days, a hypertrophic scar formed, with the corneal endothelium extending over the scarred surface." | 1.27 | Q-switched neodymium-YAG laser trabeculopuncture in monkeys. ( Epstein, DL; Melamed, S; Pei, J; Puliafito, CA, 1985) |
| "A case of extensive Bowen's disease of the skin treated successfully with topical 5-fluor-uracil is described." | 1.26 | [Therapy of morbus Bowen with 5-fluoro-uracil ointment (author's transl)]. ( Grussendorf, EI; Krause, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (22.22) | 18.7374 |
| 1990's | 19 (26.39) | 18.2507 |
| 2000's | 13 (18.06) | 29.6817 |
| 2010's | 20 (27.78) | 24.3611 |
| 2020's | 4 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, R | 1 |
| Thomas, R | 1 |
| Almukhtar, F | 1 |
| Kiran, A | 1 |
| Gomes, JT | 1 |
| Wanzeler, AMV | 1 |
| Júnior, SMA | 1 |
| Soares, RHFC | 1 |
| Oliveira, CP | 1 |
| Rodrigues, EM | 1 |
| Soares, BM | 1 |
| Alcantara, DDFA | 1 |
| Burbano, RMR | 1 |
| Tuji, FM | 1 |
| Chen, KT | 1 |
| Madison, R | 1 |
| Moore, J | 1 |
| Jin, D | 1 |
| Fleischmann, Z | 1 |
| Newberg, J | 1 |
| Schrock, A | 1 |
| Bhardwaj, N | 1 |
| Lofgren, KT | 1 |
| He, J | 1 |
| Frampton, G | 1 |
| Hegde, P | 1 |
| Fabrizio, D | 1 |
| Pishvaian, MJ | 1 |
| Ebot, E | 1 |
| Singhi, A | 1 |
| Sokol, E | 1 |
| Searle, T | 1 |
| Al-Niaimi, F | 1 |
| Ali, FR | 1 |
| Wenande, E | 1 |
| Erlendsson, AM | 1 |
| Haedersdal, M | 1 |
| Pimentel, E | 1 |
| Schmidt, J | 1 |
| Irvine, LE | 1 |
| Nassif, PS | 1 |
| Green, E | 1 |
| Wilkins, M | 1 |
| Bunce, C | 2 |
| Wormald, R | 2 |
| Cabourne, E | 1 |
| Clarke, JC | 1 |
| Schlottmann, PG | 1 |
| Evans, JR | 1 |
| Bi, XZ | 1 |
| Pan, WH | 1 |
| Yu, XP | 1 |
| Song, ZM | 1 |
| Ren, ZJ | 1 |
| Sun, M | 1 |
| Li, CH | 1 |
| Nan, KH | 1 |
| Krakowski, AC | 1 |
| Totri, CR | 1 |
| Donelan, MB | 1 |
| Shumaker, PR | 1 |
| Eilers, RE | 1 |
| Ross, EV | 1 |
| Cohen, JL | 1 |
| Ortiz, AE | 1 |
| Tsui, M | 1 |
| Tajirian, A | 1 |
| Boahene, KD | 1 |
| Owusu, JA | 1 |
| Chambers, CB | 1 |
| Moe, KS | 1 |
| Zarkovic, A | 1 |
| Chow, K | 1 |
| Mora, JS | 2 |
| Iwao, K | 1 |
| Inatani, M | 1 |
| Ogata-Iwao, M | 1 |
| Takihara, Y | 1 |
| Tanihara, H | 1 |
| How, A | 1 |
| Chua, JL | 1 |
| Charlton, A | 1 |
| Su, R | 1 |
| Lim, M | 1 |
| Kumar, RS | 1 |
| Crowston, JG | 1 |
| Wong, TT | 1 |
| Shridharani, SM | 1 |
| Magarakis, M | 1 |
| Manson, PN | 1 |
| Singh, NK | 1 |
| Basdag, B | 1 |
| Rosson, GD | 1 |
| Xu, XD | 1 |
| Liang, L | 1 |
| Chen, CS | 1 |
| Lu, B | 1 |
| Wang, NL | 1 |
| Jiang, FG | 1 |
| Zhang, XZ | 1 |
| Zhuo, RX | 1 |
| YANG, LQ | 1 |
| LAN, YQ | 1 |
| GUO, H | 1 |
| CHENG, LZ | 1 |
| FAN, JZ | 1 |
| CAI, X | 1 |
| ZHANG, LM | 1 |
| CHEN, RF | 1 |
| ZHOU, HS | 1 |
| Nikkhah, D | 1 |
| Abood, A | 1 |
| Watt, D | 1 |
| Duman, L | 1 |
| Büyükyavuz, BI | 1 |
| Altuntas, I | 1 |
| Gökcimen, A | 1 |
| Ceyhan, L | 1 |
| Darici, H | 1 |
| Aylak, F | 1 |
| Tomruk, O | 1 |
| Simon, S | 1 |
| Temlett, J | 1 |
| Chehade, M | 1 |
| Selva, D | 1 |
| Takanashi, K | 1 |
| Katsuki, S | 1 |
| Fujita, T | 1 |
| Waga, E | 1 |
| Shimodate, Y | 1 |
| Sasaki, K | 1 |
| Someya, T | 1 |
| Ohno, K | 1 |
| Fujita, M | 1 |
| Spinks, RL | 1 |
| Baker, SN | 1 |
| Jackson, A | 1 |
| Khaw, PT | 4 |
| Lemon, RN | 1 |
| Fraser, S | 1 |
| Eşme, A | 1 |
| Yildirim, C | 1 |
| Tatlipinar, S | 1 |
| Düzcan, E | 1 |
| Yaylali, V | 1 |
| Ozden, S | 1 |
| Berman, B | 1 |
| Villa, AM | 1 |
| Ramirez, CC | 1 |
| Klink, T | 1 |
| Guthoff, R | 1 |
| Grehn, F | 1 |
| Schlunck, G | 1 |
| Lemperle, G | 1 |
| Rullan, PP | 1 |
| Gauthier-Hazan, N | 1 |
| Müller, M | 1 |
| Pape, S | 1 |
| Kusserow, C | 1 |
| Hoerauf, H | 1 |
| Laqua, H | 1 |
| Labbé, A | 1 |
| Khammari, C | 1 |
| Baudouin, C | 1 |
| Reish, RG | 1 |
| Eriksson, E | 1 |
| Heuer, DK | 1 |
| Parrish, RK | 2 |
| Gressel, MG | 2 |
| Hodapp, E | 1 |
| Palmberg, PF | 1 |
| Anderson, DR | 1 |
| Galentine, P | 1 |
| Sloas, H | 1 |
| Hargett, N | 1 |
| Cupples, HP | 1 |
| Folberg, R | 1 |
| Ryan, RF | 1 |
| Litwin, MS | 1 |
| Krementz, ET | 1 |
| Khalil, AM | 1 |
| Khatib, RA | 1 |
| Mufarrij, AA | 1 |
| Tawil, AN | 1 |
| Issa, PY | 1 |
| Hurwitz, BS | 1 |
| Collignon-Brach, J | 1 |
| Jing, M | 2 |
| Xi, S | 2 |
| Chen, R | 2 |
| Schmidbauer, JM | 1 |
| Höh, H | 1 |
| Jähnig, T | 1 |
| Daberkow, I | 1 |
| Khan, U | 1 |
| Occleston, NL | 1 |
| McGrouther, DA | 1 |
| Lewandowska-Furmanik, M | 1 |
| Toczołowski, J | 1 |
| Migdal, CS | 1 |
| Fitzpatrick, RE | 1 |
| Xu, Y | 1 |
| Yang, G | 1 |
| Jin, W | 1 |
| Mackay, HJ | 1 |
| Williamson, EC | 1 |
| Vasey, P | 1 |
| Harnett, AN | 1 |
| Sprunger, DT | 1 |
| Helveston, EM | 1 |
| Evan, AP | 1 |
| Wilkins, MR | 1 |
| Kriukov, AI | 2 |
| Sharkov, SM | 2 |
| Shubin, MN | 2 |
| Kalashnikova, EA | 2 |
| Khamzalieva, RB | 2 |
| Akhmedov, ShM | 2 |
| Kaplan, LA | 1 |
| Walter, JF | 1 |
| Macknet, KD | 1 |
| Krause, H | 1 |
| Grussendorf, EI | 1 |
| Straus, DJ | 1 |
| Mausolf, FA | 1 |
| Ellerby, RA | 1 |
| McCracken, JD | 1 |
| Ophir, A | 4 |
| Ticho, U | 2 |
| Dietze, PJ | 1 |
| Feldman, RM | 1 |
| Gross, RL | 1 |
| Kitazawa, Y | 2 |
| Kawase, K | 1 |
| Matsushita, H | 1 |
| Minobe, M | 1 |
| Grierson, I | 1 |
| Hitchings, RA | 1 |
| Rice, NS | 1 |
| Aron, NK | 1 |
| Tajuri, S | 1 |
| Heath, TD | 1 |
| Lopez, NG | 1 |
| Lewis, GP | 1 |
| Stern, WH | 1 |
| Taniguchi, T | 1 |
| Nakano, Y | 1 |
| Shirato, S | 1 |
| Yamamoto, T | 1 |
| Flynn, JT | 1 |
| Melamed, S | 1 |
| Pei, J | 1 |
| Puliafito, CA | 1 |
| Epstein, DL | 1 |
| Dickinson, JT | 1 |
| Rooker, DW | 1 |
| Leonard, JR | 1 |
| Richardson, JR | 1 |
| Linton, PC | 1 |
| Leadbetter, GW | 1 |
| Peck, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489] | Phase 4 | 70 participants | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for fluorouracil and Cicatrix
| Article | Year |
|---|---|
5-Fluorouracil in Dermatology: The Diverse Uses Beyond Malignant and Premalignant Skin Disease.
Topics: Adrenal Cortex Hormones; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Dermatitis; Derma | 2021 |
Opportunities for laser-assisted drug delivery in the treatment of cutaneous disorders.
Topics: Administration, Cutaneous; Anesthetics, Local; Antineoplastic Agents; Cicatrix; Cosmetic Techniques; | 2017 |
Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma?
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Randomiz | 2018 |
5-Fluorouracil for glaucoma surgery.
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Randomized Controlled Trials as Topic; Tr | 2014 |
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Press | 2015 |
Scar Management in the Pediatric and Adolescent Populations.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimetabolites; Child; Cicatrix; Com | 2016 |
A Combination Approach to Surgical Scars.
Topics: Adrenal Cortex Hormones; Antimetabolites, Antineoplastic; Atrophy; Cicatrix; Combined Modality Thera | 2016 |
Treating Scars of the Cheek Region.
Topics: Anti-Inflammatory Agents; Antimetabolites; Cheek; Cicatrix; Combined Modality Therapy; Fluorouracil; | 2017 |
Periorbital Scar Correction.
Topics: Antimetabolites; Blepharoplasty; Cicatrix; Ectropion; Entropion; Eyelids; Fluorouracil; Humans | 2017 |
The emerging role of antineoplastic agents in the treatment of keloids and hypertrophic scars: a review.
Topics: Antineoplastic Agents; Bleomycin; Cicatrix; Fluorouracil; Humans; Hypertrophy; Interferon-alpha; Kel | 2010 |
Novel opportunities in the treatment and prevention of scarring.
Topics: Bleomycin; Botulinum Toxins, Type A; Celecoxib; Cicatrix; Fluorouracil; Humans; Immunosuppressive Ag | 2004 |
[Postoperative care after glaucoma filtration surgery].
Topics: Administration, Topical; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Immunosuppress | 2006 |
Avoiding and treating dermal filler complications.
Topics: Adipose Tissue; Adrenal Cortex Hormones; Animals; Autoimmune Diseases; Biocompatible Materials; Catt | 2006 |
[Wound healing modulation in glaucoma surgery].
Topics: Adult; Animals; Cataract Extraction; Child; Cicatrix; Eye Diseases; Filtering Surgery; Fluorouracil; | 2007 |
Scar treatments: preclinical and clinical studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bandages; Bleomycin; Cicatrix; Clinical Trials as | 2008 |
Squamous cell carcinoma of the cervix implanting in the episiotomy site.
Topics: Adult; Carcinoma, Squamous Cell; Cicatrix; Cisplatin; Doxorubicin; Episiotomy; Female; Fluorouracil; | 1993 |
[Mitomycin C in glaucoma surgery].
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Midd | 1993 |
Current techniques in wound healing modulation in glaucoma surgery.
Topics: Animals; Antimetabolites; Cataract Extraction; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; | 1996 |
Post-operative 5-Fluorouracil for glaucoma surgery.
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Trabeculectomy; Wound Healing | 2001 |
Encapsulated filtering bleb. A selective review--new deductions.
Topics: Animals; Blister; Cicatrix; Conjunctival Diseases; Fibroblasts; Fluorouracil; Glaucoma; Humans; Post | 1992 |
[Prevention of eye scarring by 5-fluorouracil].
Topics: Animals; Cicatrix; Disease Models, Animal; Eye; Fluorouracil; Glaucoma; Humans; Postoperative Compli | 1987 |
4 trials available for fluorouracil and Cicatrix
| Article | Year |
|---|---|
The chromatographic constitution of andiroba oil and his healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option.
Topics: Animals; Cicatrix; Cricetinae; Fluorouracil; Low-Level Light Therapy; Mesocricetus; Stomatitis | 2023 |
[Use of 5-fluorouracil shortly after trabeculectomy].
Topics: Antimetabolites; Cicatrix; Conjunctiva; Fluorouracil; Humans; Injections; Middle Aged; Ocular Hypert | 1996 |
Treatment of inflamed hypertrophic scars using intralesional 5-FU.
Topics: Acne Vulgaris; Adult; Aged; Anti-Inflammatory Agents; Antimetabolites; Cicatrix; Female; Fluorouraci | 1999 |
Trabeculectomy with mitomycin. A comparative study with fluorouracil.
Topics: Adult; Aged; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocula | 1991 |
47 other studies available for fluorouracil and Cicatrix
| Article | Year |
|---|---|
Use of 5-Fluorouracil Injections in Traumatic Cicatricial Malposition of Eyelids.
Topics: Cicatrix; Ectropion; Eyelids; Fluorouracil; Humans | 2022 |
A Novel HRD Signature Is Predictive of FOLFIRINOX Benefit in Metastatic Pancreatic Cancer.
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; BRCA1 Protein; BRCA2 Protein; Cicatrix; De | 2023 |
Use of 5-Fluorouracil for Management of the Thick-Skinned Nose.
Topics: Adult; Cicatrix; Cohort Studies; Esthetics; Female; Fluorouracil; Follow-Up Studies; Humans; Injecti | 2018 |
Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes.
Topics: Animals; Anterior Eye Segment; Cicatrix; Delayed-Action Preparations; Fluorouracil; Glaucoma; Glauco | 2015 |
Cicatricial Ectropion With Topical 5% Fluorouracil Cream.
Topics: Administration, Cutaneous; Aged, 80 and over; Antimetabolites, Antineoplastic; Cicatrix; Ectropion; | 2016 |
Comparison of 90-s versus 5-min intraoperative 5-fluorouracil in trabeculectomy.
Topics: Aged; Antihypertensive Agents; Antimetabolites; Blister; Cicatrix; Female; Fluorouracil; Follow-Up S | 2010 |
Restricted post-trabeculectomy bleb formation by conjunctival scarring.
Topics: Antimetabolites; Blister; Cicatrix; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; C | 2009 |
Combined treatment with bevacizumab and 5-fluorouracil attenuates the postoperative scarring response after experimental glaucoma filtration surgery.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimet | 2010 |
Peptide hydrogel as an intraocular drug delivery system for inhibition of postoperative scarring formation.
Topics: Animals; Cicatrix; Drug Carriers; Fluorouracil; Hydrogels; Oligopeptides; Ophthalmic Solutions; Post | 2010 |
Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation.
Topics: Administration, Topical; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevaciz | 2010 |
Cicatricial ectropion: a complication of topical 5-fluorouracil.
Topics: Administration, Topical; Aged, 80 and over; Cicatrix; Ectropion; Facial Dermatoses; Fluorouracil; Fo | 2012 |
The efficacy of single-dose 5-fluorouracil therapy in experimental caustic esophageal burn.
Topics: Animals; Burns, Chemical; Caustics; Cell Differentiation; Cell Division; Cicatrix; Drug Evaluation, | 2011 |
Medial rectus Botox injection with pterygium excision and autograft as a novel technique for management of recurrent pterygium.
Topics: Aged; Antimetabolites; Botulinum Toxins, Type A; Cicatrix; Combined Modality Therapy; Conjunctiva; F | 2012 |
[A case of advanced primary colorectal carcinoma accompanied by liver metastasis in which ileus developed due to marked fibrosis with cicatricial formation in primary colorectal cancer treated by chemotherapy including bevacizumab].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carc | 2012 |
Problem of dural scarring in recording from awake, behaving monkeys: a solution using 5-fluorouracil.
Topics: Animals; Antimetabolites; Cerebral Cortex; Cicatrix; Connective Tissue; Dura Mater; Electrophysiolog | 2003 |
Trabeculectomy and antimetabolites.
Topics: Antimetabolites; Cicatrix; Clinical Competence; Fluorouracil; Glaucoma; Humans; Mitomycin; Trabecule | 2004 |
Effects of intraoperative sponge mitomycin C and 5-fluorouracil on scar formation following strabismus surgery in rabbits.
Topics: Animals; Cicatrix; Connective Tissue Diseases; Fluorouracil; Intraoperative Care; Mitomycin; Oculomo | 2004 |
[Late needling with 5-fluorouracil when scarring of filtering bleb seems imminent].
Topics: Blister; Cicatrix; Cicatrix, Hypertrophic; Drug Administration Schedule; Filtering Surgery; Fluorour | 2007 |
5-fluorouracil and glaucoma filtering surgery. II. A pilot study.
Topics: Adolescent; Adult; Aged; Cataract Extraction; Child; Cicatrix; Combined Modality Therapy; Dose-Respo | 1984 |
Bilateral cicatricial ectropion following topical administration of 5-fluorouracil.
Topics: Administration, Topical; Aged; Cicatrix; Drug Eruptions; Ectropion; Facial Dermatoses; Fluorouracil; | 1981 |
5-fluorouracil and glaucoma filtering surgery: I. An animal model.
Topics: Animals; Aotus trivirgatus; Cicatrix; Combined Modality Therapy; Fibroblasts; Fluorouracil; Glaucoma | 1984 |
A new concept in the management of Marjolin's ulcers.
Topics: Administration, Topical; Adult; Carcinoma, Squamous Cell; Cicatrix; Female; Fluorouracil; Humans; Ma | 1981 |
Cicatricial ectropion: a complication of systemic fluorouracil.
Topics: Aged; Aged, 80 and over; Breast Neoplasms; Cicatrix; Colonic Neoplasms; Dexamethasone; Ectropion; Fe | 1993 |
[Subconjunctival 5-fluorouracil polyphase liposome interference with scar formation in experimental filtration surgery].
Topics: Animals; Cicatrix; Drug Carriers; Female; Filtering Surgery; Fluorouracil; Glaucoma; Liposomes; Male | 1996 |
[Antiproliferative therapy with 5-fluorouracil in erbium:YAG laser sclerostomy ab externo].
Topics: Antimetabolites; Cell Division; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; | 1996 |
Single exposures to 5-fluorouracil: a possible mode of targeted therapy to reduce contractile scarring in the injured tendon.
Topics: Animals; Antimetabolites; Cells, Cultured; Cicatrix; Collagen; Cytoskeleton; Fibroblasts; Fluorourac | 1997 |
[Injectable bioerodible polymer with 5-fluorouracil used in filtration surgery in rabbits].
Topics: Animals; Antimetabolites; Cicatrix; Drug Delivery Systems; Female; Filtering Surgery; Fluorouracil; | 1997 |
[The inhibitory effect of tissue plasminogen activator combined with 5-fluorouracil polyphase liposome on the scar formation in experimental filtration surgery].
Topics: Animals; Cicatrix; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Female; Fibrosis; Fluor | 1997 |
Recurrent inflammation in a site of previous necrotising fasciitis during intravenous CMF chemotherapy.
Topics: Abdomen; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cicatrix; Cyclophosphamid | 1999 |
Intraoperative sponge 5-fluorouracil to reduce postoperative scarring in strabismus surgery.
Topics: Administration, Topical; Animals; Antimetabolites; Cicatrix; Conjunctiva; Fluorouracil; Intraoperati | 1997 |
[Prevention of postoperative scar processes in otorhinolaryngology experimental rationale].
Topics: Antimetabolites; Cell Movement; Cicatrix; Ear Diseases; Fibroblasts; Fluorouracil; Humans; Otologic | 2001 |
[Prevention of postoperative scars in otorhinolaryngology: experimental rationale].
Topics: Cell Movement; Cicatrix; Fibroblasts; Fluorouracil; Immunosuppressive Agents; In Vitro Techniques; O | 2002 |
Hypertrophic scarring as a complication of fluorouracil therapy.
Topics: Adult; Carcinoma, Basal Cell; Cicatrix; Fluocinonide; Fluorouracil; Humans; Hypertrophy; Male; Skin | 1979 |
[Therapy of morbus Bowen with 5-fluoro-uracil ointment (author's transl)].
Topics: Bowen's Disease; Carcinoma, Squamous Cell; Cicatrix; Fluorouracil; Humans; Male; Skin Neoplasms; Tim | 1979 |
Cicatricial ectropion secondary to 5-fluorouracil therapy.
Topics: Aged; Cicatrix; Ectropion; Female; Fluorouracil; Humans; Male; Middle Aged | 1977 |
Toxic effects of 5-fluorouracil on fibroblasts following trabeculectomy.
Topics: Adult; Cicatrix; Conjunctival Diseases; Fibroblasts; Fluorouracil; Glaucoma; Humans; Inclusion Bodie | 1992 |
Intraoperative application of 5-fluorouracil during trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1992 |
Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Cicatrix; Conjunctiva; Dosage F | 1991 |
5-fluorouracil and beyond.
Topics: Child; Cicatrix; Fluorouracil; Glaucoma; Humans; Trabeculectomy | 1991 |
Postburn scar carcinoma.
Topics: Adult; Aged; Burns; Carcinoma, Squamous Cell; Cicatrix; Combined Modality Therapy; Female; Fluoroura | 1989 |
Fluoropyrimidine treatment of ocular cicatricial disease.
Topics: Animals; Cell Division; Cicatrix; Eye Diseases; Fibroblasts; Floxuridine; Fluorouracil; Osmolar Conc | 1986 |
5-Fluorouracil for trabeculectomy in glaucoma.
Topics: Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Pos | 1987 |
Problems in strabismus management.
Topics: Adolescent; Child; Cicatrix; Female; Fluorouracil; Humans; Male; Postoperative Complications; Strabi | 1986 |
Q-switched neodymium-YAG laser trabeculopuncture in monkeys.
Topics: Animals; Cicatrix; Fluorouracil; Hyaluronic Acid; Injections; Intraocular Pressure; Laser Therapy; M | 1985 |
Minor surgery for benign and malignant facial lesions.
Topics: Acne Vulgaris; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cicatrix; Cortisone; Curettage; Cyst | 1974 |
A new concept in the treatment of stomal stenosis.
Topics: Cesium Isotopes; Child; Cicatrix; Fluorouracil; Humans; Ileum; Male; Mucus; Skin Diseases; Skin Tran | 1972 |
Hypertrophic scar after cryotherapy and topical tretinoin.
Topics: Administration, Topical; Carcinoma, Basal Cell; Carmustine; Cicatrix; Connective Tissue; Cryosurgery | 1973 |