fluorouracil has been researched along with Cicatrix, Hypertrophic in 49 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Cicatrix, Hypertrophic: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed by enlargement and overgrowth of cicatricial tissue and regresses spontaneously.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 9.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "To compare the use of intralesional triamcinolone acetonide and its combination with 5 flourouracil in the treatment of keloid and hypertrophic scars in terms of reduction in initial height of the scar." | 9.19 | Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Bashir, MM; Khan, FA; Khan, MA, 2014) |
| "TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments." | 9.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "To compare the clinical response of keloidal and hypertrophic scars after treatment with intralesional corticosteroid alone or combined with 5-fluorouracil (5-FU), 5-FU alone, and the 585-nm flashlamp-pumped pulsed-dye laser (PDL)." | 9.10 | Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. ( Fitzpatrick, RE; Manuskiatti, W, 2002) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 7.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| " This review assesses recurrence and the reporting of recurrence in pathologic scar after treatment with intralesional triamcinolone (TAC) in combination with another intralesional agent." | 7.01 | Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents. ( Chandy, RJ; Feldman, SR; Khan, D; Rimmer, SN, 2023) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 6.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| " The aim of this study was to evaluate and compare the therapeutic efficacy of dermabrasion, dermabrasion combined with 5% 5-fluorouracil cream, and dermabrasion combined with topical placentrex gel in the management of localized stable vitiligo." | 6.73 | Comparative evaluation of the therapeutic efficacy of dermabrasion, dermabrasion combined with topical 5% 5-fluorouracil cream, and dermabrasion combined with topical placentrex gel in localized stable vitiligo. ( Gupta, RR; Mahajan, BB; Ohri, A; Sethi, S, 2007) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that usually cause major physical, psychological, and cosmetic problems." | 6.72 | New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2006) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 6.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| "The objective was to establish the safety and efficacy of intralesional 5-fluorouracil (5-FU) for the treatment of keloids and hypertrophic scars." | 5.30 | Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. ( Ahmad, S; Khalid, FA; Mehrose, MY; Mujahid, AM; Rehman, SU; Saleem, M; Tarar, MN; Yousaf, MA, 2019) |
| "To compare the use of intralesional triamcinolone acetonide and its combination with 5 flourouracil in the treatment of keloid and hypertrophic scars in terms of reduction in initial height of the scar." | 5.19 | Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Bashir, MM; Khan, FA; Khan, MA, 2014) |
| "TAC may be beneficial for the short-term treatment of hypertrophic scars and keloids; however, 5-FU, 5-FU+TAC, and verapamil may produce superior results for medium- and long-term treatments." | 5.12 | The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis. ( Li, Y; Wei, X; Zhuang, Z, 2021) |
| "To compare the clinical response of keloidal and hypertrophic scars after treatment with intralesional corticosteroid alone or combined with 5-fluorouracil (5-FU), 5-FU alone, and the 585-nm flashlamp-pumped pulsed-dye laser (PDL)." | 5.10 | Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments. ( Fitzpatrick, RE; Manuskiatti, W, 2002) |
| "To evaluate the effectiveness of combined ablative fractional CO2 laser and topically applied 5-fluorouracil (5-FU) or verapamil hydrochloride in the treatment of hypertrophic scars (HTSs) and keloids and to examine their possible effects on TGF-β1 expression." | 3.91 | The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study. ( Abd El Azez, TA; Abdel Rahman, SH; Hussein, MS; Sabry, HH; Sanad, RR, 2019) |
| "Intralesional treatments for keloid and hypertrophic scars may be the most reliable treatment option to improve pathologic scars, while laser treatment may have specific benefits for Fitzpatrick skin types I-III over types IV-VI." | 3.01 | Treatment of traumatic hypertrophic scars and keloids: a systematic review of randomized control trials. ( Alam, M; Anvery, N; Asadbeigi, SN; Christensen, RE; Dirr, MA; Hisham, FI; Ibrahim, SA; Jain-Poster, K; Kang, BY; Kim, K; Merkel, EA; Poon, E; Reynolds, KA; Worley, B, 2023) |
| " This review assesses recurrence and the reporting of recurrence in pathologic scar after treatment with intralesional triamcinolone (TAC) in combination with another intralesional agent." | 3.01 | Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents. ( Chandy, RJ; Feldman, SR; Khan, D; Rimmer, SN, 2023) |
| "As 5-fluorouracil was associated with fewer adverse events, these findings support the use of a nonsteroidal agent in the management of traumatic scars by laser-assisted therapy." | 2.90 | Treatment of Hypertrophic Scars Using Laser-Assisted Corticosteroid Versus Laser-Assisted 5-Fluorouracil Delivery. ( Daoud, A; Rudnick, A; Waibel, JS; Wulkan, AJ, 2019) |
| "Different approaches are used aiming to improve these scars, including intralesional corticosteroids, surgery and more recently, laser therapy." | 2.82 | Laser therapy for treating hypertrophic and keloid scars. ( da Silva, CA; da Silva, EM; Kuczynski, U; Leszczynski, R; Pinto, ACPN, 2022) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 2.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| " The aim of this study was to evaluate and compare the therapeutic efficacy of dermabrasion, dermabrasion combined with 5% 5-fluorouracil cream, and dermabrasion combined with topical placentrex gel in the management of localized stable vitiligo." | 2.73 | Comparative evaluation of the therapeutic efficacy of dermabrasion, dermabrasion combined with topical 5% 5-fluorouracil cream, and dermabrasion combined with topical placentrex gel in localized stable vitiligo. ( Gupta, RR; Mahajan, BB; Ohri, A; Sethi, S, 2007) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that usually cause major physical, psychological, and cosmetic problems." | 2.72 | New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2006) |
| "5-fluorouracil has proven to be an effective therapy in the treatment of a variety of dermatologic conditions." | 2.58 | Intralesional and Laser-Assisted 5-Fluorouracil in Dermatologic Disease: A Systematic Review. ( Alkousakis, T; Cameron, MC; Fathi, R; Prince, GT, 2018) |
| " We aimed to compare the efficacy and safety of TAC alone and in combination with 5-FU for the treatment of hypertrophic scars and keloids." | 2.55 | Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis. ( Fan, B; Feng, S; Lin, W; Ren, Y; Wei, Z; Zhou, X, 2017) |
| " The patient underwent 10 treatment sessions with the 595-nm long-pulsed dye laser followed immediately by the 1450-nm diode laser in combination with intralesional triamcinolone and 5-fluorouracil." | 1.36 | 595-nm long pulsed dye laser and 1450-nm diode laser in combination with intralesional triamcinolone/5-fluorouracil for hypertrophic scarring following a phenol peel. ( Friedman, PM; Glaich, AS; Goldberg, LH; Katz, TM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (22.45) | 29.6817 |
| 2010's | 22 (44.90) | 24.3611 |
| 2020's | 16 (32.65) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, C | 1 |
| Mukovozov, I | 1 |
| Jazdarehee, A | 1 |
| Rai, R | 1 |
| Sachdeva, M | 1 |
| Shunmugam, M | 1 |
| Zaslavsky, K | 1 |
| Byun, S | 1 |
| Barankin, B | 1 |
| Erlendsson, AM | 1 |
| Rosenberg, LK | 1 |
| Lerche, CM | 1 |
| Togsverd-Bo, K | 1 |
| Wiegell, SR | 1 |
| Karmisholt, K | 1 |
| Philipsen, PA | 1 |
| Hansen, ACN | 1 |
| Janfelt, C | 1 |
| Holmes, J | 1 |
| Rossi, A | 1 |
| Haedersdal, M | 1 |
| Leszczynski, R | 1 |
| da Silva, CA | 1 |
| Pinto, ACPN | 1 |
| Kuczynski, U | 1 |
| da Silva, EM | 1 |
| Wu, W | 1 |
| Zhao, Y | 1 |
| Chen, Y | 1 |
| Zhong, A | 1 |
| Rios, JES | 1 |
| Almeida, FM | 1 |
| Limongi, RM | 1 |
| Lino-Junior, RS | 1 |
| de Araújo, LA | 1 |
| de Ávila, MP | 1 |
| Magacho, L | 1 |
| Worley, B | 1 |
| Kim, K | 1 |
| Jain-Poster, K | 1 |
| Reynolds, KA | 1 |
| Merkel, EA | 1 |
| Kang, BY | 1 |
| Dirr, MA | 1 |
| Anvery, N | 1 |
| Christensen, RE | 1 |
| Hisham, FI | 1 |
| Ibrahim, SA | 1 |
| Asadbeigi, SN | 1 |
| Poon, E | 1 |
| Alam, M | 1 |
| Dika, E | 1 |
| Mussi, M | 1 |
| Lambertini, M | 1 |
| Vaccari, S | 1 |
| Baraldi, C | 1 |
| Campione, E | 1 |
| Scotti, B | 1 |
| Stancic, BH | 1 |
| Zengarini, C | 1 |
| Rimmer, SN | 1 |
| Chandy, RJ | 1 |
| Khan, D | 1 |
| Feldman, SR | 1 |
| Artzi, O | 2 |
| Koren, A | 2 |
| Niv, R | 1 |
| Mehrabi, JN | 1 |
| Mashiah, J | 1 |
| Friedman, O | 1 |
| Feng, Y | 1 |
| Sun, ZL | 2 |
| Yuan, FL | 2 |
| Teplyi, V | 1 |
| Grebchenko, K | 1 |
| Wang, J | 1 |
| Wu, QY | 1 |
| Li, X | 1 |
| Lv, GZ | 1 |
| Jiang, ZY | 1 |
| Liao, XC | 1 |
| Liu, MZ | 1 |
| Fu, ZH | 1 |
| Min, DH | 1 |
| Yu, XT | 1 |
| Guo, GH | 1 |
| Mustoe, TA | 1 |
| Huang, J | 1 |
| Chen, J | 2 |
| Wo, Y | 5 |
| Wang, X | 1 |
| Zhang, Y | 5 |
| Chen, X | 1 |
| Zhang, Z | 5 |
| Biskup, E | 1 |
| Zhuang, Z | 1 |
| Li, Y | 2 |
| Wei, X | 1 |
| Singla, P | 1 |
| Dietert, JB | 1 |
| Hurst, EA | 1 |
| Prince, GT | 1 |
| Cameron, MC | 1 |
| Fathi, R | 1 |
| Alkousakis, T | 1 |
| Salameh, F | 1 |
| Sprecher, E | 1 |
| Khalid, FA | 2 |
| Mehrose, MY | 2 |
| Saleem, M | 2 |
| Yousaf, MA | 1 |
| Mujahid, AM | 2 |
| Rehman, SU | 2 |
| Ahmad, S | 2 |
| Tarar, MN | 2 |
| Waibel, JS | 1 |
| Wulkan, AJ | 1 |
| Rudnick, A | 1 |
| Daoud, A | 1 |
| Amin, M | 1 |
| Sabry, HH | 1 |
| Abdel Rahman, SH | 1 |
| Hussein, MS | 1 |
| Sanad, RR | 1 |
| Abd El Azez, TA | 1 |
| Ledon, JA | 1 |
| Savas, J | 1 |
| Franca, K | 1 |
| Chacon, A | 1 |
| Nouri, K | 1 |
| Arno, AI | 1 |
| Gauglitz, GG | 4 |
| Barret, JP | 1 |
| Jeschke, MG | 1 |
| Wang, K | 1 |
| Mao, X | 2 |
| Su, W | 2 |
| Li, K | 1 |
| Cui, D | 4 |
| Khan, MA | 1 |
| Bashir, MM | 1 |
| Khan, FA | 1 |
| Heppt, MV | 1 |
| Breuninger, H | 1 |
| Reinholz, M | 1 |
| Feller-Heppt, G | 1 |
| Ruzicka, T | 1 |
| Trace, AP | 1 |
| Enos, CW | 1 |
| Mantel, A | 1 |
| Harvey, VM | 1 |
| Poetschke, J | 1 |
| Çalıskan, E | 1 |
| Gamsızkan, M | 1 |
| Açıkgöz, G | 1 |
| Durmuş, M | 1 |
| Toklu, S | 1 |
| Doğrul, A | 1 |
| Kurt, A | 1 |
| Tunca, M | 1 |
| Ren, Y | 1 |
| Zhou, X | 1 |
| Wei, Z | 1 |
| Lin, W | 1 |
| Fan, B | 1 |
| Feng, S | 1 |
| Wang, XQ | 2 |
| Liu, YK | 2 |
| Wang, ZY | 1 |
| Jiang, YZ | 1 |
| Lu, SL | 2 |
| Darougheh, A | 2 |
| Asilian, A | 2 |
| Shariati, F | 2 |
| Haurani, MJ | 1 |
| Foreman, K | 1 |
| Yang, JJ | 1 |
| Siddiqui, A | 1 |
| Juckett, G | 1 |
| Hartman-Adams, H | 1 |
| Qing, C | 1 |
| Donaldson, MR | 1 |
| Stetson, CL | 1 |
| Katz, TM | 1 |
| Glaich, AS | 1 |
| Goldberg, LH | 1 |
| Friedman, PM | 1 |
| He, R | 2 |
| Qian, Y | 2 |
| Wang, D | 2 |
| Chen, H | 1 |
| Pu, Z | 1 |
| Pavicic, T | 1 |
| Manuskiatti, W | 1 |
| Fitzpatrick, RE | 1 |
| Müller, M | 1 |
| Pape, S | 1 |
| Kusserow, C | 1 |
| Hoerauf, H | 1 |
| Laqua, H | 1 |
| Sethi, S | 1 |
| Mahajan, BB | 1 |
| Gupta, RR | 1 |
| Ohri, A | 1 |
| Goldan, O | 1 |
| Weissman, O | 1 |
| Regev, E | 1 |
| Haik, J | 1 |
| Winkler, E | 1 |
| Lebwohl, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Post-Surgical Intralesional Injection With Triamcinolone Versus Triamcinolone Plus Fluorouracil in the Treatment of Keloids[NCT04710719] | 7 participants (Actual) | Interventional | 2021-02-01 | Completed | |||
| Effect of Cryotherpy on Hypertrophic Scar[NCT04532840] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2019-04-15 | Active, not recruiting | ||
| The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair[NCT03219580] | Phase 3 | 50 participants (Anticipated) | Interventional | 2017-05-20 | Enrolling by invitation | ||
| Open, Non-comparative, Multicentre Clinical Investigation to Evaluate the Performance and Safety of the Medical Device Plenhyage® (Polymerised Polynucleotides Dermal Filler) in the Treatment of Dermal Tissue Defects[NCT05239117] | 48 participants (Actual) | Interventional | 2022-03-30 | Active, not recruiting | |||
| Assessing and Improving Patient Knowledge About Keloids[NCT01176877] | 40 participants (Actual) | Interventional | 2010-08-31 | Completed | |||
| Intra-lesional ACE Inhibitor for Treatment of Hypertrophic Scars[NCT05259137] | Phase 2/Phase 3 | 30 participants (Anticipated) | Interventional | 2023-08-31 | Not yet recruiting | ||
| Effect of Pulse Width of a 595-nm Flashlamp-pumped Pulsed-dye Laser on the Treatment Response of Keloidal and Hypertrophic Sternotomy Scars[NCT00142441] | 19 participants | Interventional | 2003-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: immediately before and after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | Immediate post-educational lecture score | |
| Keloid Scar | 12.9 | 18.3 |
All subjects completed a written questionnaire to assess knowledge about keloid scars before an educational lecture about keloids, immediately after the educational lecture about keloids, and 3 months after the educational lecture about keloids. This written questionnaire to assess knowledge about keloid scars contained 19 questions related to risk factors for developing keloid scars, keloid scar prevention, and keloid scar treatment. A correct response to a question was awarded 1 point and all correct responses were summed to achieve a total score. Possible total score ranged from 0 to 19. A score of 0 is associated with worse knowledge about keloid scars and a score of 19 is associated with better knowledge about keloid scars. (NCT01176877)
Timeframe: before and 3 months after a 5 minute educational lecture
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Pre-educational lecture score | 3 months post-educational lecture score | |
| Keloid Scars | 13.2 | 16.8 |
16 reviews available for fluorouracil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Management of hypertrophic scars in adults: A systematic review and meta-analysis.
Topics: Adult; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Silicones; Treatment Outcome; Triamcino | 2022 |
Laser therapy for treating hypertrophic and keloid scars.
Topics: Adrenal Cortex Hormones; Adult; Aluminum; Atrophy; Carbon Dioxide; Child; Cicatrix, Hypertrophic; Di | 2022 |
Comparing the Efficacy of Multiple Drugs Injection for the Treatment of Hypertrophic Scars and Keloid: A Network Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Network Meta-Analysis; Treatment Outcome | 2023 |
Treatment of traumatic hypertrophic scars and keloids: a systematic review of randomized control trials.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Hypertrophy; Injections, Intralesional; Keloid; Qualit | 2023 |
Recurrence rates in the treatment of keloids and hypertrophic scars with intralesional triamcinolone combined with other intralesional agents.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Treatment Outcome; Triamcinolone | 2023 |
Efficacy and Safety of Intralesional Triamcinolone Versus Combination of Triamcinolone with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-analysis.
Topics: Cicatrix, Hypertrophic; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; | 2020 |
The safety and efficacy of intralesional triamcinolone acetonide for keloids and hypertrophic scars: A systematic review and meta-analysis.
Topics: Atrophy; Burns; Cicatrix, Hypertrophic; Culture Media; Fluorouracil; Humans; Injections, Intralesion | 2021 |
Intralesional and Laser-Assisted 5-Fluorouracil in Dermatologic Disease: A Systematic Review.
Topics: Animals; Antimetabolites, Antineoplastic; Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, | 2018 |
Intralesional treatment for keloids and hypertrophic scars: a review.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites; Bleomycin; Calcium Channel Bl | 2013 |
Up-to-date approach to manage keloids and hypertrophic scars: a useful guide.
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aminoquinolines; Anti-Inflammatory Agents; Antineop | 2014 |
Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges.
Topics: Adjuvants, Immunologic; Aminoquinolines; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Anti | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Current options for the treatment of pathological scarring.
Topics: Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Humans; Keloid; Laser Therapy | 2016 |
Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Fluorouracil; H | 2017 |
Antimitotic drug injections and radiotherapy: a review of the effectiveness of treatment for hypertrophic scars and keloids.
Topics: Adrenal Cortex Hormones; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antimitotic A | 2008 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
Management of keloids and hypertrophic scars.
Topics: Bleomycin; Cicatrix, Hypertrophic; Cryotherapy; Fluorouracil; Glucocorticoids; Humans; Keloid; Recur | 2009 |
A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Bleomycin; Cicatrix, Hypertrophic; Colchicine; Drug Ther | 2009 |
10 trials available for fluorouracil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
A one-time pneumatic jet-injection of 5-fluorouracil and triamcinolone acetonide for treatment of hypertrophic scars-A blinded randomized controlled trial.
Topics: Cicatrix, Hypertrophic; Drug Therapy, Combination; Fluorouracil; Humans; Injections, Intralesional; | 2022 |
THE USAGE OF RADIOFREQUENCY ABLATION FOR TREATMENT OF KELOIDS AND HYPERTROPHIC SCARS.
Topics: Adult; Catheter Ablation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; H | 2019 |
Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial.
Topics: Adult; Body Piercing; Burns; Cicatrix, Hypertrophic; Double-Blind Method; Drug Therapy, Combination; | 2019 |
Treatment of Hypertrophic Scars Using Laser-Assisted Corticosteroid Versus Laser-Assisted 5-Fluorouracil Delivery.
Topics: Cicatrix, Hypertrophic; Dermatologic Agents; Double-Blind Method; Fluorouracil; Glucocorticoids; Hum | 2019 |
Intralesional triamcinolone alone and in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.
Topics: Adult; Cicatrix, Hypertrophic; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, | 2014 |
Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Double-Blind Method; Drug | 2009 |
In vitro study of ethosome penetration in human skin and hypertrophic scar tissue.
Topics: Administration, Cutaneous; Adult; Cicatrix, Hypertrophic; Female; Fluorouracil; Humans; Immunosuppre | 2012 |
Treatment response of keloidal and hypertrophic sternotomy scars: comparison among intralesional corticosteroid, 5-fluorouracil, and 585-nm flashlamp-pumped pulsed-dye laser treatments.
Topics: Adrenal Cortex Hormones; Adult; Aged; Biopsy, Needle; Cicatrix, Hypertrophic; Drug Therapy, Combinat | 2002 |
New combination of triamcinolone, 5-Fluorouracil, and pulsed-dye laser for treatment of keloid and hypertrophic scars.
Topics: Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Drug Therapy, Combination; Female; Fluorou | 2006 |
Comparative evaluation of the therapeutic efficacy of dermabrasion, dermabrasion combined with topical 5% 5-fluorouracil cream, and dermabrasion combined with topical placentrex gel in localized stable vitiligo.
Topics: Administration, Topical; Adult; Cicatrix, Hypertrophic; Combined Modality Therapy; Dermabrasion; Der | 2007 |
23 other studies available for fluorouracil and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
The effect of bevacizumab, 5-fluorouracil, and triamcinolone on the healing modulation of surgical wounds in rats.
Topics: Animals; Bevacizumab; Cicatrix, Hypertrophic; Collagen; Fluorouracil; Rats; Surgical Wound; Treatmen | 2023 |
Postsurgical hypertrophic scars after nonmelanoma skin cancer surgical excision: clinical and confocal microscopy outcomes of topical 5-fluorouracil in an adjuvant setting.
Topics: Adjuvants, Immunologic; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Microscopy, Confocal; | 2023 |
A new approach in the treatment of pediatric hypertrophic burn scars: Tixel-associated topical triamcinolone acetonide and 5-fluorouracil delivery.
Topics: Administration, Cutaneous; Age Factors; Burns; Child; Child, Preschool; Cicatrix, Hypertrophic; Comb | 2020 |
Comments on "A new approach in the treatment of pediatric hypertrophic burn scars: Tixel-associated topical triamcinolone acetonide and 5-fluorouracil delivery".
Topics: Burns; Child; Cicatrix, Hypertrophic; Fluorouracil; Humans; Keloid; Triamcinolone Acetonide | 2020 |
Comments on"Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomisedcontrol trial".
Topics: Burns; Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolon | 2020 |
Invited Discussion On: Efficacy and Safety of Intralesional Triamcinolone Versus Combination of Triamcinolone with 5-Fluorouracil in the Treatment of Keloids and Hypertrophic Scars: A Systematic Review and Meta-Analysis.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolone | 2020 |
CO
Topics: Animals; Cicatrix, Hypertrophic; Collagen Type I; Disease Models, Animal; Fluorouracil; Lasers, Gas; | 2021 |
Cells to Surgery Quiz: January 2018.
Topics: Administration, Cutaneous; Arm; Arm Injuries; Bleomycin; Botulinum Toxins, Type A; Cicatrix, Hypertr | 2018 |
Novel Stereoscopic Optical System for Objectively Measuring Above-Surface Scar Volume-First-Time Quantification of Responses to Various Treatment Modalities.
Topics: Adult; Cicatrix, Hypertrophic; Cryosurgery; Dermatologic Agents; Feasibility Studies; Female; Fluoro | 2018 |
Reply to comments on "comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial".
Topics: Burns; Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid; Triamcinolon | 2020 |
The Efficacy of Combining Fractional Carbon Dioxide Laser With Verapamil Hydrochloride or 5-Fluorouracil in the Treatment of Hypertrophic Scars and Keloids: A Clinical and Immunohistochemical Study.
Topics: Administration, Topical; Cicatrix, Hypertrophic; Combined Modality Therapy; Dose Fractionation, Radi | 2019 |
Enhanced in vivo delivery of 5-fluorouracil by ethosomal gels in rabbit ear hypertrophic scar model.
Topics: Administration, Cutaneous; Animals; Antimetabolites; Cell Line; Chemistry, Pharmaceutical; Cicatrix, | 2014 |
Current Strategies in the Treatment of Scars and Keloids.
Topics: Antimetabolites, Antineoplastic; Botulinum Toxins, Type A; Cicatrix, Hypertrophic; Cryosurgery; Fluo | 2015 |
Intralesional treatments for hypertrophic scars: comparison among corticosteroid, 5-fluorouracil and botulinum toxin in rabbit ear hypertrophic scar model.
Topics: Adrenal Cortex Hormones; Animals; Botulinum Toxins; Cicatrix, Hypertrophic; Fluorouracil; Immunosupp | 2016 |
5-Fluorouracil treatment of problematic scars.
Topics: Adult; Antimetabolites; Cicatrix, Hypertrophic; Disease Progression; Female; Fluorouracil; Follow-Up | 2009 |
Hypertrophic scarring after treatment with fluorouracil, 2%, in pyruvic acid, 98%, for verruca vulgaris.
Topics: Adolescent; Cicatrix, Hypertrophic; Fluorouracil; Humans; Immunosuppressive Agents; Male; Pyruvic Ac | 2010 |
595-nm long pulsed dye laser and 1450-nm diode laser in combination with intralesional triamcinolone/5-fluorouracil for hypertrophic scarring following a phenol peel.
Topics: Aged; Chemexfoliation; Cicatrix, Hypertrophic; Combined Modality Therapy; Female; Fluorouracil; Gluc | 2010 |
Preparation and characterization of different sizes of ethosomes encapsulated with 5-fluorouracil and its experimental study of permeability in hypertrophic scar.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Microscopy, Electron, Scanning; Microscopy, Electron, | 2010 |
Preparation of ethosomes and deformable liposomes encapsulated with 5-fluorouracil and their investigation of permeability and retention in hypertrophic scar.
Topics: Adolescent; Adult; Cicatrix, Hypertrophic; Fluorouracil; Humans; Liposomes; Microscopy, Electron, Tr | 2011 |
[Emerging strategies for the prevention and therapy of excessive scars].
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Aminoquinolines; Botulinum Toxins, Type A; Cicatrix | 2012 |
[Late needling with 5-fluorouracil when scarring of filtering bleb seems imminent].
Topics: Blister; Cicatrix; Cicatrix, Hypertrophic; Drug Administration Schedule; Filtering Surgery; Fluorour | 2007 |
Treatment of postdermabrasion facial hypertrophic and keloid scars with intralesional 5-Fluorouracil injections.
Topics: Aged; Antimetabolites, Antineoplastic; Cicatrix, Hypertrophic; Face; Female; Fluorouracil; Humans; I | 2008 |
From the literature: intralesional 5-FU in the treatment of hypertrophic scars and keloids: clinical experience.
Topics: Cicatrix, Hypertrophic; Fluorouracil; Humans; Injections, Intralesional; Keloid | 2000 |