fluorouracil has been researched along with Chylopericardium in 11 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the clinical application value of the 5-fluorouracil (5-FU) sustained-release particles implanted along the cardiac tangent direction into malignant pericardial effusion (MPCE)." | 7.81 | Therapeutic effects of 5-fluorouracil sustained-release particles in 81 malignant pericardial effusion patients. ( Cui, WC; Dong, L; Gao, Y; Ji, YL; Li, P; Li, RZ; Liang, XH; Pang, MX; Xue, LF, 2015) |
| "A diagnosis of cardiac tamponade was made and pericardiocentesis for continuous drainage was carried out cytologically, the effusion was class V and showed evidence of pericardial metastasis of breast cancer." | 5.31 | [A case of recurring breast cancer causing pericardial metastasis showing a good response following local treatment with methotrexate]. ( Furukawa, J; Katsumoto, Y; Maruyama, K; Maruyama, N; Nakaguchi, K; Nakamura, M; Okajima, S; Shingai, T; Sue, F; Yoshiwara, W, 2001) |
| "This study aimed to investigate the clinical application value of the 5-fluorouracil (5-FU) sustained-release particles implanted along the cardiac tangent direction into malignant pericardial effusion (MPCE)." | 3.81 | Therapeutic effects of 5-fluorouracil sustained-release particles in 81 malignant pericardial effusion patients. ( Cui, WC; Dong, L; Gao, Y; Ji, YL; Li, P; Li, RZ; Liang, XH; Pang, MX; Xue, LF, 2015) |
| "The case history is reported of a 51-year-old man with metastatic colonic carcinoma who was receiving a continuous 5-fluorouracil infusion via a central venous catheter and who developed cardiac perforation and pericardial effusion." | 3.69 | Cardiac perforation associated with continuous infusional chemotherapy. ( Cooper, RA; James, RD; Taylor, KJ, 1996) |
| "The purpose of this study was the evaluation of the effectiveness of intrapericardial administration of tetracycline, 5-fluorouracil and cisplatin in patients with recurrent malignant pericardial effusion." | 3.69 | New approaches to the management and treatment of malignant pericardial effusion. ( Burakowski, J; Fijałkowska, A; Filipecki, S; Szturmowicz, M; Tomkowski, W, 1997) |
| "A diagnosis of cardiac tamponade was made and pericardiocentesis for continuous drainage was carried out cytologically, the effusion was class V and showed evidence of pericardial metastasis of breast cancer." | 1.31 | [A case of recurring breast cancer causing pericardial metastasis showing a good response following local treatment with methotrexate]. ( Furukawa, J; Katsumoto, Y; Maruyama, K; Maruyama, N; Nakaguchi, K; Nakamura, M; Okajima, S; Shingai, T; Sue, F; Yoshiwara, W, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, Y | 1 |
| Iijima, H | 1 |
| Isohashi, F | 1 |
| Tsujii, Y | 1 |
| Fujinaga, T | 1 |
| Nagai, K | 1 |
| Yoshii, S | 1 |
| Sakatani, A | 1 |
| Hiyama, S | 1 |
| Shinzaki, S | 1 |
| Makino, T | 1 |
| Yamasaki, M | 1 |
| Ogawa, K | 1 |
| Doki, Y | 1 |
| Takehara, T | 1 |
| Ji, YL | 1 |
| Li, RZ | 1 |
| Xue, LF | 1 |
| Li, P | 1 |
| Liang, XH | 1 |
| Dong, L | 1 |
| Gao, Y | 1 |
| Cui, WC | 1 |
| Pang, MX | 1 |
| Cooper, RA | 1 |
| James, RD | 1 |
| Taylor, KJ | 1 |
| Tomkowski, W | 1 |
| Szturmowicz, M | 1 |
| Fijałkowska, A | 1 |
| Burakowski, J | 1 |
| Filipecki, S | 1 |
| Lerner-Tung, MB | 1 |
| Chang, AY | 1 |
| Ong, LS | 1 |
| Kreiser, D | 1 |
| Wu, J | 1 |
| Liang, S | 1 |
| Zhang, Z | 1 |
| Yukiiri, K | 1 |
| Mizushige, K | 1 |
| Ueda, T | 1 |
| Kohno, M | 1 |
| Nakaguchi, K | 1 |
| Furukawa, J | 1 |
| Maruyama, N | 1 |
| Nakamura, M | 1 |
| Shingai, T | 1 |
| Maruyama, K | 1 |
| Katsumoto, Y | 1 |
| Okajima, S | 1 |
| Sue, F | 1 |
| Yoshiwara, W | 1 |
| Shinde, SR | 1 |
| Shaha, PB | 1 |
| Shetty, PA | 1 |
| Smith, FE | 1 |
| Lane, M | 1 |
| Hudgins, PT | 1 |
| Lokich, JJ | 1 |
11 other studies available for fluorouracil and Chylopericardium
| Article | Year |
|---|---|
The heart's exposure to radiation increases the risk of cardiac toxicity after chemoradiotherapy for superficial esophageal cancer: a retrospective cohort study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Cardiotoxicity; Chemoradi | 2019 |
Therapeutic effects of 5-fluorouracil sustained-release particles in 81 malignant pericardial effusion patients.
Topics: Antimetabolites, Antineoplastic; Delayed-Action Preparations; Female; Fluorouracil; Humans; Lung Neo | 2015 |
Cardiac perforation associated with continuous infusional chemotherapy.
Topics: Antineoplastic Agents; Catheterization, Central Venous; Colonic Neoplasms; Fluorouracil; Heart Injur | 1996 |
New approaches to the management and treatment of malignant pericardial effusion.
Topics: Adult; Aged; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineop | 1997 |
Pharmacokinetics of intrapericardial administration of 5-fluorouracil.
Topics: Adenocarcinoma; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Area Under Curve; Bre | 1997 |
[Percutanous trans-catheter intervention for the diagnosis and treatment of malignant pericardial effusion, with a report of 50 cases].
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Catheteriz | 1996 |
Second primary cardiac B-cell lymphoma after radiation therapy and chemotherapy--a case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Carcinoma, Squamous Cell; Cisp | 2001 |
[A case of recurring breast cancer causing pericardial metastasis showing a good response following local treatment with methotrexate].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; C | 2001 |
Cardiac tamponade as the only initial feature of malignancy: a case report and review of the literature.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiac Tamponade; Common Col | 1986 |
Conservative management of malignant pericardial effusion.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cardiomegaly; Female; Fluorouracil; Follow-Up Studies | 1974 |
The management of malignant pericardial effusions.
Topics: Angiography; Cardiac Tamponade; Fluorouracil; Gold; Heart Neoplasms; Humans; Lung; Mechlorethamine; | 1973 |