fluorouracil has been researched along with Chronic Primary Open Angle Glaucoma in 108 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 8.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To determine whether the use of postoperative subconjunctival 5-fluorouracil (5-FU) reduces the risk of trabeculectomy bleb failure after uncomplicated small incisional cataract surgery." | 7.76 | Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery. ( Salmon, JF; Shahid, H, 2010) |
| "To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil." | 7.72 | Transient, profound cataract associated with intracameral 5-fluorouracil. ( Libre, PE, 2003) |
| "Subconjunctival injections of 5-Fluorouracil after filtering surgery are helpful to control high-risk glaucoma, but there are several disadvantages of this treatment as fistulas of the conjunctiva, corneal surface problems, discomfort for the patient, difficult follow-up and a potential toxicity on the ciliary epithelium that may be pronounced in some cases." | 7.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "These include young patients, those with pigmentary glaucoma, secondary glaucoma, angle recession glaucoma, aphakic or pseudophakic glaucoma, and patients requiring reoperation." | 6.67 | Intraoperative mitomycin C in complicated glaucomas. ( Dogra, A; Kaur, J; Singh, G, 1993) |
| "We examined the safety and efficacy of 5-fluorouracil in eyes with open-angle glaucoma undergoing combined cataract removal and filtration surgery." | 5.07 | 5-Fluorouracil after primary combined filtration surgery. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Shields, MB; Wong, PC, 1994) |
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 4.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To determine the outcome of needling with adjunctive 5-fluorouracil (5-FU) in patients with a failing Ahmed glaucoma valve (AGV) implant, and to identify predictors of long-term intraocular pressure (IOP) control." | 3.83 | Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs. ( Floriani, I; Hollander, L; Katsanos, A; Konstas, AG; Poli, D; Quaranta, L, 2016) |
| "To determine whether the use of postoperative subconjunctival 5-fluorouracil (5-FU) reduces the risk of trabeculectomy bleb failure after uncomplicated small incisional cataract surgery." | 3.76 | Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery. ( Salmon, JF; Shahid, H, 2010) |
| " Intraocular pressure, visual acuity, complications and numbers of injections of 5-fluorouracil, suture removal, needling procedures and visits to ophthalmologists were recorded for 2 years." | 3.75 | Trabeculectomy with an active postoperative regimen: results and resource utilization. ( Alm, A; Niemelä, P; Taube, AB, 2009) |
| "To report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil." | 3.72 | Transient, profound cataract associated with intracameral 5-fluorouracil. ( Libre, PE, 2003) |
| "To determine and compare the intraocular pressure (IOP) lowering effects of single-incision combined phacoemulsification and trabeculectomy with phacoemulsification done after previous trabeculectomy, both with an intraoperative dose of 5-fluorouracil (5-FU)." | 3.70 | Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil. ( Donoso, R; Rodríguez, A, 2000) |
| "The revision of a failed filtering bleb using mitomycin C was performed in 40 eyes (28 eyes with primary open angle glaucoma and 12 eyes with secondary open angle glaucoma) in which the previous trabeculectomy using 5-fluorouracil had failed to control intraocular pressure (IOP)." | 3.69 | [Surgical revision of failed filtering bleb with mitomycin C]. ( Hara, T; Shirato, S, 1997) |
| "Forty consecutive case patients who underwent temporal corneal phacoemulsification combined with superior trabeculectomy plus low-dose 5-fluorouracil (case [combined surgery] group) and 40 control patients, matched for age race, preoperative intraocular pressure (IOP), number of preoperative antiglaucoma medications, and number of 5-fluorouracil injections, who underwent trabeculectomy alone plus low-dose 5-fluorouracil (control [trabeculectomy] group)." | 3.69 | Temporal corneal phacoemulsification combined with superior trabeculectomy. A retrospective case-control study. ( Caprioli, J; Park, HJ; Weitzman, M, 1997) |
| " In the 56 eyes where 5-fluorouracil was not used, the mean intraocular pressure (IOP) on diagnosis was 33." | 3.69 | Intraocular pressure control following microtrabeculectomy. ( Spencer, AF; Vernon, SA, 1995) |
| "Six patients, each with one eye that had previously undergone circular buckling surgery for the repair of retinal detachment before or followed by cataract extraction with or without intraocular lens implantation, underwent trabeculectomy with 5-fluorouracil (5-FU) for intractable glaucoma." | 3.68 | Trabeculectomy with 5-fluorouracil subsequent to circular buckling operation and cataract extraction. ( Ophir, A; Ticho, U, 1992) |
| "Subconjunctival injections of 5-Fluorouracil after filtering surgery are helpful to control high-risk glaucoma, but there are several disadvantages of this treatment as fistulas of the conjunctiva, corneal surface problems, discomfort for the patient, difficult follow-up and a potential toxicity on the ciliary epithelium that may be pronounced in some cases." | 3.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 27 primary open-angle glaucoma patients (33 eyes) who had never been operated upon (25 eyes) or had undergone single trabeculectomy that failed to reduce IOP (8 eyes)." | 3.67 | Long-term results of 5-fluorouracil trabeculectomy for primary open-angle glaucoma. ( Kitazawa, Y; Shimizu, U; Taniguchi, T, 1989) |
| "68 eyes with chronic open angle glaucoma were included in a randomised trial of intraoperative 5-FU versus placebo." | 2.70 | A randomised trial of the effect of intraoperative 5-FU on the outcome of trabeculectomy in east Africa. ( Khaw, PT; Yorston, D, 2001) |
| "The use of low-dose subconjunctival 5-FU (mean dosage of 24." | 2.69 | Long-term outcome of primary glaucoma triple procedure with adjunctive 5-fluorouracil. ( Glover, BK; Hughes, BA; Juzych, MS; Kim, C; Kim, YY; O'Grady, JM; Ren, J; Shin, DH, 1998) |
| "When comparing the different types of open angle glaucoma, no difference was found in terms of reduction in IOP, number of patients requiring antiglaucoma medications, or success rate." | 2.69 | Deep sclerectomy with collagen implant: medium term results. ( Karlen, ME; Mermoud, A; Sanchez, E; Schnyder, CC; Sickenberg, M, 1999) |
| "Forty-two open angle glaucoma patients with uncontrolled intra-ocular pressure and with no risk factor of bleb fibrosis, underwent a NPDS." | 2.69 | [Deep nonpenetrating sclerectomy and open angle glaucoma. Intermediate results from the first operated patients]. ( Hamard, H; Hamard, P; Kopel, J; Plaza, L; Quesnot, S, 1999) |
| "Mitomycin C-treated eyes received an average of 0." | 2.68 | 5-Fluorouracil and mitomycin C in pseudophakic patients. ( Belkin, JK; Lamping, KA, 1995) |
| "Intraocular pressure was 20 mmHg or lower in 94% of 5-FU eyes and in 73% of control eyes (P < 0." | 2.67 | 5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Wong, PC, 1994) |
| "These include young patients, those with pigmentary glaucoma, secondary glaucoma, angle recession glaucoma, aphakic or pseudophakic glaucoma, and patients requiring reoperation." | 2.67 | Intraoperative mitomycin C in complicated glaucomas. ( Dogra, A; Kaur, J; Singh, G, 1993) |
| " The optimum route of administration and dosing regimen of anti-VEGF antibodies and their positioning in comparison with 5-fluorouracil and mitomycin C are uncertain." | 2.47 | Anti--vascular endothelial growth factor therapy in glaucoma filtration surgery. ( Barton, K; Mathew, R, 2011) |
| "The average total bleb score during follow-up in the success group was always higher than in the failure group, but there was no statistically significant difference at any time." | 1.37 | The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy. ( Ellinger, P; Grehn, F; Guthoff, R; Kann, G; Klink, J; Klink, T, 2011) |
| "Juvenile-onset Open Angle Glaucoma (JOAG) has been proposed to be a small subset of Primary Open Angle Glaucoma (POAG) and on a continual spectrum of Primary Open Angle Glaucoma." | 1.35 | Bilateral ocular hypertension with rapidly progressive optic neuropathy in a teen. ( Byrne, E; Hua, LV; Yudcovitch, L, 2009) |
| "Primary open angle glaucoma is characterized by late presentation." | 1.34 | Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria. ( Lawan, A, 2007) |
| "5-Fluorouracil (5-FU) has been used in patients with a pre-existing bleb, undergoing cataract surgery, but there are no published reports for or against its use in such cases." | 1.34 | Phacoemulsification in patients with previous trabeculectomy: role of 5-fluorouracil. ( Arora, S; Corridan, PG; Sharma, TK, 2007) |
| "Within this group, blebs were classified into three different categories according to their optical coherence tomography pattern: type A (featuring a thick wall and a single large fluid-filled space), type B (featuring a thin wall and multiple large fluid-filled spaces) and type C (featuring multiple, irregular and flattened fluid-filled spaces)." | 1.33 | Filtering blebs imaging by optical coherence tomography. ( Barboni, P; Savini, G; Zanini, M, 2005) |
| "All the complications related to the bleb leak resolved after bleb reconstruction." | 1.31 | [Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps]. ( Ayed, T; Hamard, H; Hamard, P; Quesnot, S; Tazartes, M, 2001) |
| "Both patients had ocular hypotony and decreased visual acuity following these injections." | 1.29 | Hypotonic maculopathy after trabeculectomy with postoperative use of 5-fluorouracil. ( Altan, T; Bavbek, T; Kazokoglu, H; Temel, A, 1994) |
| "A 71-year-old white woman with primary open angle glaucoma received trabeculectomy with antimetabolite." | 1.29 | Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite. ( Kaufman, PL; Kee, C, 1994) |
| " Our study may provide data on the appropriate dosage and indications for the use of this drug after glaucoma surgery." | 1.28 | Trabeculectomy with 5-fluorouracil. ( Iwata, K; Nanba, K; Sawaguchi, S; Watanabe, J, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.93) | 18.7374 |
| 1990's | 57 (52.78) | 18.2507 |
| 2000's | 31 (28.70) | 29.6817 |
| 2010's | 16 (14.81) | 24.3611 |
| 2020's | 3 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Wałek, E | 1 |
| Przeździecka-Dołyk, J | 1 |
| Helemejko, I | 1 |
| Misiuk-Hojło, M | 1 |
| Ang, BCH | 1 |
| Seen, S | 1 |
| Kumaran, A | 1 |
| De Leon, JMS | 1 |
| Seah, SKL | 1 |
| Foster, PJ | 6 |
| Gazzard, G | 7 |
| Htoon, HM | 3 |
| Khaw, PT | 9 |
| Aung, T | 8 |
| Husain, R | 6 |
| Başer, EF | 1 |
| Seymenoğlu, RG | 1 |
| Shihadeh, W | 1 |
| Massad, I | 1 |
| Khader, Y | 1 |
| Al-Rawi, A | 1 |
| Alshalakhti, T | 1 |
| Wirbelauer, C | 1 |
| Mertens, CN | 1 |
| Vinod, K | 1 |
| Gedde, SJ | 1 |
| Feuer, WJ | 1 |
| Panarelli, JF | 1 |
| Chang, TC | 1 |
| Chen, PP | 1 |
| Parrish, RK | 1 |
| Wong, MH | 1 |
| Ang, BC | 1 |
| Wong, TT | 3 |
| Oen, FT | 4 |
| Seah, SK | 5 |
| Na, JH | 1 |
| Sung, KR | 1 |
| Shin, JA | 1 |
| Moon, JI | 1 |
| Quaranta, L | 2 |
| Floriani, I | 1 |
| Hollander, L | 1 |
| Poli, D | 1 |
| Katsanos, A | 1 |
| Konstas, AG | 1 |
| Wilson, ME | 1 |
| Gupta, P | 1 |
| Tran, KV | 1 |
| Arora, KS | 1 |
| Lee, CH | 1 |
| Chang, DS | 1 |
| Friedman, DS | 1 |
| Taube, AB | 1 |
| Niemelä, P | 1 |
| Alm, A | 1 |
| Rekas, M | 1 |
| Wierzbowska, J | 1 |
| Lewczuk, K | 1 |
| Siemiatkowska, A | 1 |
| Stankiewicz, A | 1 |
| Devereux, JG | 2 |
| Minassian, D | 1 |
| Tan, SB | 1 |
| Chew, PT | 4 |
| Hua, LV | 1 |
| Byrne, E | 1 |
| Yudcovitch, L | 1 |
| Shahid, H | 1 |
| Salmon, JF | 1 |
| Hoehn, R | 1 |
| Lamparter, J | 1 |
| Pfeiffer, N | 1 |
| Vossmerbaeumer, U | 1 |
| Simsek, T | 1 |
| Firat, P | 1 |
| Citirik, M | 1 |
| Ozdamar, Y | 1 |
| Elgin, U | 1 |
| Klink, T | 1 |
| Kann, G | 1 |
| Ellinger, P | 1 |
| Klink, J | 1 |
| Grehn, F | 1 |
| Guthoff, R | 1 |
| Tan, YL | 1 |
| Tsou, PF | 1 |
| Tan, GS | 1 |
| Perera, SA | 1 |
| Ho, CL | 1 |
| Mathew, R | 1 |
| Barton, K | 1 |
| Day, AC | 1 |
| Machin, D | 1 |
| Liang, S | 1 |
| Bunce, C | 3 |
| Zahid, S | 1 |
| Musch, DC | 2 |
| Niziol, LM | 1 |
| Lichter, PR | 2 |
| Libre, PE | 1 |
| Carassa, RG | 1 |
| Bettin, P | 1 |
| Fiori, M | 1 |
| Brancato, R | 1 |
| Oen, F | 1 |
| Chew, P | 1 |
| Seah, S | 1 |
| Detry-Morel, M | 2 |
| De Temmerman, S | 1 |
| Aydin, A | 1 |
| Wollstein, G | 1 |
| Price, LL | 1 |
| Fujimoto, JG | 1 |
| Schuman, JS | 1 |
| Zalish, M | 1 |
| Oron, Y | 1 |
| Geyer, O | 1 |
| Ahmed, II | 2 |
| Shaarawy, T | 1 |
| O'Brart, DP | 2 |
| Shiew, M | 1 |
| Edmunds, B | 1 |
| Paris, G | 1 |
| Zhao, M | 1 |
| Sponsel, WE | 1 |
| Lim, MC | 1 |
| Hoh, ST | 1 |
| Savini, G | 1 |
| Zanini, M | 1 |
| Barboni, P | 1 |
| Tello, CA | 1 |
| Sharma, TK | 1 |
| Arora, S | 1 |
| Corridan, PG | 1 |
| Hueber, A | 1 |
| Esser, JM | 1 |
| Kociok, N | 1 |
| Welsandt, G | 1 |
| Lüke, C | 1 |
| Roters, S | 1 |
| Esser, PJ | 1 |
| Lawan, A | 1 |
| Vernon, SA | 1 |
| Spencer, AF | 1 |
| Chalfin, S | 1 |
| Memmen, JE | 1 |
| Uva, MG | 1 |
| Gagliano, C | 1 |
| Ott, JP | 1 |
| Ferrigno, G | 1 |
| Sciacca, S | 1 |
| Reibaldi, A | 1 |
| Lamping, KA | 1 |
| Belkin, JK | 1 |
| Altan, T | 1 |
| Temel, A | 1 |
| Bavbek, T | 1 |
| Kazokoglu, H | 1 |
| Oh, SY | 1 |
| Youn, DH | 1 |
| Kim, DM | 1 |
| Hong, C | 1 |
| Kee, C | 1 |
| Kaufman, PL | 1 |
| Mazey, BJ | 1 |
| Siegel, MJ | 1 |
| Siegel, LI | 1 |
| Dunn, SP | 1 |
| Goldenfeld, M | 2 |
| Krupin, T | 2 |
| Ruderman, JM | 2 |
| Wong, PC | 2 |
| Rosenberg, LF | 2 |
| Ritch, R | 4 |
| Liebmann, JM | 4 |
| Gieser, DK | 2 |
| Reinhard, T | 1 |
| Klüppel, M | 1 |
| Sundmacher, R | 1 |
| Shields, MB | 1 |
| Hayashi, M | 1 |
| Ibaraki, N | 1 |
| Tsuru, T | 1 |
| Hurvitz, LM | 1 |
| O'Grady, JM | 2 |
| Juzych, MS | 3 |
| Shin, DH | 3 |
| Lemon, LC | 1 |
| Swendris, RP | 2 |
| Egbert, PR | 2 |
| Williams, AS | 1 |
| Singh, K | 2 |
| Dadzie, P | 1 |
| Egbert, TB | 1 |
| Singh, G | 1 |
| Kaur, J | 1 |
| Dogra, A | 1 |
| Khatana, AK | 1 |
| Parrow, KA | 1 |
| Oppenheim, B | 1 |
| Ortiz, JM | 1 |
| Smith, MF | 2 |
| Doyle, JW | 2 |
| Smith, TJ | 2 |
| Ashton, P | 1 |
| Susanna, R | 1 |
| Takahashi, W | 1 |
| Nicolela, M | 1 |
| Spiegel, D | 1 |
| Sachs, H | 1 |
| Yanes, G | 1 |
| Lamba, PA | 2 |
| Pandey, PK | 2 |
| Raina, UK | 2 |
| Krishna, V | 2 |
| Gandolfi, SA | 1 |
| Vecchi, M | 1 |
| Park, HJ | 1 |
| Weitzman, M | 1 |
| Caprioli, J | 1 |
| Greenfield, DS | 1 |
| Wanichwecharungruang, B | 1 |
| Yamagami, S | 1 |
| Hamada, N | 1 |
| Araie, M | 3 |
| Shirato, S | 4 |
| Hara, T | 2 |
| Fechtner, RD | 1 |
| Byrd, S | 1 |
| Budenz, D | 1 |
| Gallenga, PE | 2 |
| Mastropasqua, L | 2 |
| Carpineto, P | 2 |
| Ciancaglini, M | 2 |
| Zuppardi, E | 2 |
| Ren, J | 1 |
| Kim, YY | 1 |
| Hughes, BA | 1 |
| Kim, C | 1 |
| Glover, BK | 1 |
| Lobefalo, L | 1 |
| Mermoud, A | 2 |
| Schnyder, CC | 2 |
| Sickenberg, M | 2 |
| Chiou, AG | 1 |
| Hédiguer, SE | 1 |
| Faggioni, R | 1 |
| Migdal, C | 1 |
| Karlen, ME | 1 |
| Sanchez, E | 1 |
| el Sayyad, F | 1 |
| el-Rashood, A | 1 |
| Helal, M | 1 |
| Hisham, M | 1 |
| el-Maghraby, A | 1 |
| Hamard, P | 2 |
| Plaza, L | 1 |
| Kopel, J | 1 |
| Quesnot, S | 2 |
| Hamard, H | 2 |
| Freedman, SF | 1 |
| McCormick, K | 1 |
| Cox, TA | 1 |
| Donoso, R | 1 |
| Rodríguez, A | 1 |
| Pires, RT | 1 |
| Chokshi, A | 1 |
| Tseng, SC | 1 |
| Membrey, WL | 2 |
| Poinoosawmy, DP | 2 |
| Hitchings, RA | 2 |
| Bettelli, S | 1 |
| Gandolfo, E | 1 |
| Alsagoff, Z | 1 |
| Chee, CK | 1 |
| Wong, JS | 1 |
| Fitzke, FW | 1 |
| Tazartes, M | 1 |
| Ayed, T | 1 |
| Yorston, D | 1 |
| Gillespie, BW | 1 |
| Guire, KE | 1 |
| Janz, NK | 1 |
| Wren, PA | 1 |
| Mills, RP | 1 |
| Uchida, S | 1 |
| Suzuki, Y | 1 |
| Shigeeda, T | 1 |
| Rowlands, E | 1 |
| Islam, N | 1 |
| Noury, AM | 1 |
| Hodge, W | 1 |
| Saheb, N | 1 |
| Balazsi, G | 1 |
| Kasner, O | 1 |
| Demailly, P | 1 |
| Kretz, G | 1 |
| Ophir, A | 2 |
| Ticho, U | 2 |
| Sherwood, MB | 1 |
| Shoji, N | 1 |
| Nakano, Y | 1 |
| Terry, S | 1 |
| Bansal, RK | 1 |
| Gupta, A | 1 |
| Phelan, MJ | 2 |
| Skuta, GL | 2 |
| Whiteside-Michel, J | 1 |
| Watanabe, J | 1 |
| Iwata, K | 1 |
| Sawaguchi, S | 1 |
| Nanba, K | 1 |
| Wilson, RP | 1 |
| Steinmann, WC | 1 |
| Loane, ME | 1 |
| Weinreb, RN | 1 |
| Beckman, RL | 1 |
| Sofinski, SJ | 1 |
| Greff, LJ | 1 |
| Oates, DC | 1 |
| Simmons, RJ | 1 |
| Peterson, MR | 1 |
| Stanley, SA | 1 |
| Krug, JH | 1 |
| Melamed, S | 1 |
| Cohen, JS | 1 |
| Taniguchi, T | 1 |
| Kitazawa, Y | 1 |
| Shimizu, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Combined Phacotrabeculectomy and Trabeculectomy Only in the Treatment of Primary Angle-closure Glaucoma[NCT01298635] | 31 participants (Actual) | Interventional | 2005-01-31 | Completed | |||
| Anterior Segment Optical Coherence Tomography Findings in Patients With Ahmed Glaucoma Drainage Implants With Either a Pericardial Patch Graft and Fibrin Tissue Glue or a Partial-Thickness Scleral Flap and Conventional Sutures[NCT00453024] | Phase 2 | 40 participants (Anticipated) | Interventional | 2007-02-28 | Recruiting | ||
| Multidrug Resistance After Trabeculectomy With Mitomycin C[NCT00449631] | 30 participants | Observational | Completed | ||||
| Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489] | Phase 4 | 70 participants | Interventional | 2004-09-30 | Completed | ||
| Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy[NCT00695747] | 95 participants (Actual) | Interventional | 1998-01-31 | Completed | |||
| [NCT00000149] | Phase 3 | 0 participants | Interventional | 1993-10-31 | Active, not recruiting | ||
| Phacoemulsification Combined With Trabeculectomy Versus Phacoemulsification Combined With Trabeculotomy for Treatment of Chronic Angle Closure Glaucoma[NCT04683055] | 50 participants (Actual) | Interventional | 2020-10-28 | Completed | |||
| Glaucoma Eye Drop Instillation: Impact of Education[NCT01416415] | 119 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Not practical to continue due interim results) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fluorouracil and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
[Role of Intraoperative Indirect Channelography in Glaucoma Stent Implantation].
Topics: Administration, Ophthalmic; Aged, 80 and over; Bevacizumab; Combined Modality Therapy; Female; Fluor | 2017 |
Anti--vascular endothelial growth factor therapy in glaucoma filtration surgery.
Topics: Alkylating Agents; Angiogenesis Inhibitors; Filtering Surgery; Fluorouracil; Glaucoma, Open-Angle; H | 2011 |
New aspects in the surgical treatment of glaucoma.
Topics: Combined Modality Therapy; Cryosurgery; Fluorouracil; Glaucoma, Open-Angle; Humans; Light Coagulatio | 1991 |
32 trials available for fluorouracil and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
The Singapore 5-fluorouracil trial: intraocular pressure outcomes at 8 years.
Topics: Antihypertensive Agents; Antimetabolites; Combined Modality Therapy; Double-Blind Method; Fluorourac | 2013 |
The singapore 5-Fluorouracil trabeculectomy study: effects on intraocular pressure control and disease progression at 3 years.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease Progression; Double | 2009 |
Central corneal thickness and glaucoma in East Asian people.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alkylating Agents; Asian People; Case-Control Studies; Cornea | 2011 |
Cataract surgery after trabeculectomy: the effect on trabeculectomy function.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Female; Fluorouracil; Follow-Up Studies; Glaucoma | 2012 |
Risk of endophthalmitis and other long-term complications of trabeculectomy in the Collaborative Initial Glaucoma Treatment Study (CIGTS).
Topics: Antimetabolites; Cataract Extraction; Endophthalmitis; Fluorouracil; Follow-Up Studies; Glaucoma, Op | 2013 |
Viscocanalostomy versus trabeculectomy in white adults affected by open-angle glaucoma: a 2-year randomized, controlled trial.
Topics: Aged; Anterior Eye Segment; Conjunctiva; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open- | 2003 |
Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucomas.
Topics: Antimetabolites; Cross-Sectional Studies; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, O | 2003 |
A randomised, prospective study comparing trabeculectomy with viscocanalostomy with adjunctive antimetabolite usage for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Cataract; Female; Filtering Surgery; Fluor | 2004 |
5-Fluorouracil and mitomycin C in pseudophakic patients.
Topics: Aged; Cataract Extraction; Conjunctiva; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraope | 1995 |
5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Exfoliation Syndrome; Female; Fluorouracil; Foll | 1994 |
5-Fluorouracil after primary combined filtration surgery.
Topics: Aged; Cataract; Cataract Extraction; Combined Modality Therapy; Female; Fluorouracil; Glaucoma, Open | 1994 |
Trabeculectomy, phacoemulsification, and posterior chamber lens implantation with and without 5-fluorouracil.
Topics: Aged; Cataract Extraction; Chronic Disease; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma, | 1993 |
A prospective trial of intraoperative fluorouracil during trabeculectomy in a black population.
Topics: Adult; Aged; Aged, 80 and over; Black People; Female; Fluorouracil; Follow-Up Studies; Ghana; Glauco | 1993 |
Intraoperative mitomycin C in complicated glaucomas.
Topics: Adult; Age Factors; Aged; Aphakia; Drug Evaluation; Female; Fluorouracil; Glaucoma; Glaucoma, Open-A | 1993 |
Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Female; Fluorouracil; Glaucoma, Angle-Closure; | 1996 |
5-fluorouracil in combined trabeculectomy and clear-cornea phacoemulsification with posterior chamber intraocular lens implantation. A one-year randomized, controlled clinical trial.
Topics: Antimetabolites; Cataract; Cornea; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; In | 1997 |
Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas.
Topics: Administration, Topical; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Angle-C | 1997 |
Risk of hypotony after primary trabeculectomy with antifibrotic agents in a black west African population.
Topics: Fluorouracil; Follow-Up Studies; Ghana; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Intraope | 1998 |
Delayed postoperative use of 5-fluorouracil in primary open angle glaucoma.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Fluorouracil; Follow-Up Studies; Glauc | 1997 |
Long-term outcome of primary glaucoma triple procedure with adjunctive 5-fluorouracil.
Topics: Aged; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; | 1998 |
Delayed post-operative use of 5-fluorouracil as an adjunct in medically uncontrolled open angle glaucoma.
Topics: Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Drug Administration Schedule; Fema | 1998 |
Deep sclerectomy with collagen implant: medium term results.
Topics: Aged; Collagen; Female; Fibrosis; Fluorouracil; Glaucoma, Open-Angle; Humans; Male; Postoperative Co | 1999 |
Fornix-based versus limbal-based conjunctival flaps in initial trabeculectomy with postoperative 5-fluorouracil: four-year follow-up findings.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Fluorouracil; Follow-Up Studies; Glauc | 1999 |
[Deep nonpenetrating sclerectomy and open angle glaucoma. Intermediate results from the first operated patients].
Topics: Administration, Topical; Aged; Collagen; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Ang | 1999 |
Efficacy of sulodexide as adjunct in trabeculectomy. A two-year randomized clinical study.
Topics: Chemotherapy, Adjuvant; Fibrinolytic Agents; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; | 2000 |
Indocyanine green anterior segment angiography for studying conjunctival vascular changes after trabeculectomy.
Topics: Adult; Aged; Anterior Eye Segment; Capillary Permeability; Conjunctiva; Female; Fluorescein Angiogra | 2001 |
A randomised trial of the effect of intraoperative 5-FU on the outcome of trabeculectomy in east Africa.
Topics: Antimetabolites; Chronic Disease; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Int | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
A randomised, prospective study comparing trabeculectomy augmented with antimetabolites with a viscocanalostomy technique for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Fo | 2002 |
Daunorubicin versus 5-fluoro-uracil in surgical treatment of primary open angle glaucoma: a prospective study.
Topics: Aged; Daunorubicin; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Injection | 1992 |
Encapsulated filtering bleb and subconjunctival 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Fibroblasts; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; | 1992 |
Use of trabeculectomy with postoperative 5-fluorouracil in patients requiring extremely low intraocular pressure levels to limit further glaucoma progression.
Topics: Aged; Aged, 80 and over; Chronic Disease; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-An | 1991 |
73 other studies available for fluorouracil and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma Drainage Implants; Glaucoma, Op | 2020 |
Visual field progression 8 years after trabeculectomy in Asian eyes: results from The Singapore 5-Fluorouracil Study.
Topics: Adult; Aged; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Hum | 2020 |
Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma.
Topics: Aged; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular | 2021 |
Comparison of the Outcomes of Trabeculectomy with 5-Fluorouracil versus Ologen Implant in Primary Open-Angle Glaucoma.
Topics: Collagen; Drug Implants; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Glycosaminog | 2017 |
Practice Preferences for Glaucoma Surgery: A Survey of the American Glaucoma Society.
Topics: Alkylating Agents; Cataract; Female; Filtering Surgery; Fluorouracil; Glaucoma Drainage Implants; Gl | 2017 |
Antifibrotic effects of pirfenidone on Tenon's fibroblasts in glaucomatous eyes: comparison with mitomycin C and 5-fluorouracil.
Topics: Actins; Adult; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Catara | 2015 |
Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs.
Topics: Aged; Antimetabolites; Combined Modality Therapy; Female; Filtering Surgery; Fluorouracil; Follow-Up | 2016 |
Results From a Modified Bleb Needling Procedure With Continuous Infusion Performed in the Operating Room.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocular Press | 2016 |
Trabeculectomy with an active postoperative regimen: results and resource utilization.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Glaucoma; Glaucoma, Open-Angle; Humans; Injections; Intraoc | 2009 |
The effectiveness of phacodeepsclerectomy performed with implantation sk-gel and T-flux--12 months observations.
Topics: Absorbable Implants; Aged; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Gels; | 2008 |
Bilateral ocular hypertension with rapidly progressive optic neuropathy in a teen.
Topics: Adolescent; Antimetabolites; Disease Progression; Female; Fluorouracil; Fundus Oculi; Glaucoma, Open | 2009 |
Use of 5-Fluorouracil injections to reduce the risk of trabeculectomy bleb failure after cataract surgery.
Topics: Aged; Aged, 80 and over; Cataract; Cataract Extraction; Conjunctiva; Drug Administration Schedule; F | 2010 |
Seizures following subconjunctival 5-FU therapy.
Topics: Aged; Alkylating Agents; Antimetabolites; Combined Modality Therapy; Conjunctiva; Fibrosis; Fluorour | 2011 |
Short-term effects of subconjunctival injections of 5-fluorouracil on conjunctival epithelium.
Topics: Adult; Aged; Antimetabolites; Apoptosis; Conjunctiva; Epithelium; Female; Fluorouracil; Glaucoma, Op | 2010 |
The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy.
Topics: Antimetabolites; Blister; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Follow-Up St | 2011 |
Postoperative complications after glaucoma surgery for primary angle-closure glaucoma vs primary open-angle glaucoma.
Topics: Aged; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Gonioscopy; Humans; Incid | 2011 |
Transient, profound cataract associated with intracameral 5-fluorouracil.
Topics: Antimetabolites, Antineoplastic; Cataract; Filtering Surgery; Fluorouracil; Glaucoma, Open-Angle; Hu | 2003 |
[Assessment of nonpenetrating deep sclerectomy with reticulated hyaluronic acid implant SKGEL and/or preoperative application of 5-luorouracil: results of 2 and a half years].
Topics: Adult; Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Hyaluronic Acid; | 2003 |
Optical coherence tomography assessment of retinal nerve fiber layer thickness changes after glaucoma surgery.
Topics: Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Interferometry; Intraocu | 2003 |
Outcome of consecutive trabeculectomy.
Topics: Adolescent; Adult; Aged; Antimetabolites; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intrao | 2004 |
Viscocanalostomy versus trabeculectomy.
Topics: Anterior Eye Segment; Antimetabolites, Antineoplastic; Conjunctiva; Fluorouracil; Glaucoma, Open-Ang | 2004 |
Operative revision of non-functioning filtering blebs with 5-fluorouracil to regain intraocular pressure control.
Topics: Adult; Aged; Antimetabolites; Conjunctiva; Female; Filtering Surgery; Fluorouracil; Glaucoma, Open-A | 2004 |
Use of surodex in phacotrabeculectomy surgery.
Topics: Anterior Eye Segment; Dexamethasone; Drug Delivery Systems; Fluorouracil; Follow-Up Studies; Glaucom | 2005 |
Filtering blebs imaging by optical coherence tomography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Child; Combined Modality Thera | 2005 |
Failed trabeculectomy.
Topics: Antimetabolites; Conjunctiva; Fistula; Fluorouracil; Glaucoma Drainage Implants; Glaucoma, Open-Angl | 2005 |
Phacoemulsification in patients with previous trabeculectomy: role of 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Antimetabolites; Drug Administration Schedule; Dru | 2007 |
Mitomycin C induces multidrug resistance in glaucoma surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; ATP Binding Cassette Transporter, Sub | 2008 |
Pattern of presentation and outcome of surgical management of primary open angle glaucoma in Kano, Northern Nigeria.
Topics: Adult; Age Distribution; Aged; Antimetabolites; Blindness; Female; Fluorouracil; Glaucoma, Open-Angl | 2007 |
Intraocular pressure control following microtrabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pres | 1995 |
Corneal endothelial toxic effect secondary to fluorouracil needle bleb revision.
Topics: Corneal Edema; Endothelium, Corneal; Fluorouracil; Glaucoma, Open-Angle; Humans; Needles; Reoperatio | 1995 |
[Experiences with sclerostomy with the Holmium laser].
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glaucom | 1994 |
Hypotonic maculopathy after trabeculectomy with postoperative use of 5-fluorouracil.
Topics: Adult; Female; Fluorescein Angiography; Fluorouracil; Fundus Oculi; Glaucoma, Open-Angle; Humans; Ma | 1994 |
The effects of intraoperative mitomycin-C or 5-fluorouracil on glaucoma filtering surgery.
Topics: Adult; Aged; Animals; Filtering Surgery; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, Open-Angle | 1994 |
Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite.
Topics: Aged; Female; Fluorescein Angiography; Fluorouracil; Fundus Oculi; Glaucoma, Open-Angle; Humans; Int | 1994 |
Corneal endothelial toxic effect secondary to fluorouracil needle bleb revision.
Topics: Aged; Corneal Edema; Endothelium, Corneal; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Male; | 1994 |
[5-fluorouracil injection treatment after fistulating glaucoma operations].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Combined Modality Therapy; Female; Fluorouracil; | 1993 |
Lamellar keratoplasty after trabeculectomy with 5-fluorouracil.
Topics: Corneal Diseases; Corneal Transplantation; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Middl | 1994 |
Corneal opacification after 5-fluorouracil injections.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Corneal Opacity; Female; Fluorouracil; Glaucoma, Open- | 1994 |
Needling revision of failed filtering blebs with adjunctive 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Fluorouracil; Follow-Up Studies; Glaucoma, | 1993 |
Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil.
Topics: Adult; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Macula Lutea; Male; Ocular | 1993 |
Use of oversized bandage soft contact lenses in the management of early hypotony following filtration surgery.
Topics: Aged; Aged, 80 and over; Antimetabolites; Contact Lenses, Hydrophilic; Female; Fluorouracil; Follow- | 1996 |
Sustained-release subconjunctival 5-fluorouracil.
Topics: Aged; Antimetabolites; Conjunctiva; Delayed-Action Preparations; Drug Implants; Female; Fluorouracil | 1996 |
Late bleb leakage after trabeculectomy with 5-fluorouracil or mitomycin C.
Topics: Adult; Aged; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular | 1996 |
[Single dose intraoperative administration of 5-fluorouracil (5-FU) in trabeculectomy. Long-term results of a pilot study].
Topics: Aged; Antimetabolites; Cell Division; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open-Ang | 1996 |
Temporal corneal phacoemulsification combined with superior trabeculectomy. A retrospective case-control study.
Topics: Aged; Aged, 80 and over; Antimetabolites; Case-Control Studies; Cornea; Female; Fluorouracil; Glauco | 1997 |
Pseudotumor cerebri appearing with unilateral papilledema after trabeculectomy.
Topics: Acetazolamide; Adult; Antimetabolites; Carbonic Anhydrase Inhibitors; Female; Fluorouracil; Fundus O | 1997 |
Risk factors for unsatisfactory intraocular pressure control in combined trabeculectomy and cataract surgery.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; Fluorouracil; Follo | 1997 |
[Surgical revision of failed filtering bleb with mitomycin C].
Topics: Adult; Aged; Aged, 80 and over; Female; Filtering Surgery; Fluorouracil; Follow-Up Studies; Glaucoma | 1997 |
Management of coexisting pseudophakic bullous keratopathy and open-angle glaucoma.
Topics: Administration, Topical; Aged; Cataract Extraction; Corneal Diseases; Female; Fluorouracil; Follow-U | 1998 |
Comparison of deep sclerectomy with collagen implant and trabeculectomy in open-angle glaucoma.
Topics: Aged; Collagen; Female; Fluorouracil; Follow-Up Studies; Glaucoma Drainage Implants; Glaucoma, Open- | 1999 |
Mitomycin C-augumented trabeculectomy with postoperative wound modulation in pediatric glaucoma.
Topics: Adolescent; Chemotherapy, Adjuvant; Child; Child, Preschool; Female; Fluorouracil; Follow-Up Studies | 1999 |
Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil.
Topics: Aged; Antimetabolites; Cataract; Conjunctiva; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections | 2000 |
Amniotic membrane transplantation or conjunctival limbal autograft for limbal stem cell deficiency induced by 5-fluorouracil in glaucoma surgeries.
Topics: Aged; Amnion; Cell Transplantation; Conjunctiva; Corneal Diseases; Epithelial Cells; Epithelium, Cor | 2000 |
Glaucoma surgery with or without adjunctive antiproliferatives in normal tension glaucoma: 1 intraocular pressure control and complications.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; I | 2000 |
Glaucoma surgery with or without adjunctive antiproliferatives in normal tension glaucoma: 2 Visual field progression.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; I | 2001 |
[Prognostic outcome of leaking filtering blebs reconstruction with rotational conjunctival flaps].
Topics: Adult; Aged; Antimetabolites; Blister; Combined Modality Therapy; Conjunctival Diseases; Female; Flu | 2001 |
Non penetrating deep sclerectomy (NPDS) with SKGEL implant and/or 5-fluorouracile (5-FU).
Topics: Female; Fluorouracil; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hyaluronic Acid; Int | 2001 |
Long-term follow-up of initial 5-fluorouracil trabeculectomy in primary open-angle glaucoma in Japanese patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Follow-Up Studie | 2001 |
Treatment of encapsulated blebs with 30-gauge needling and injection of low-dose 5-fluorouracil.
Topics: Adult; Aged; Conjunctival Diseases; Cysts; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, | 1992 |
Trabeculectomy with 5-fluorouracil subsequent to circular buckling operation and cataract extraction.
Topics: Adult; Aged; Atropine; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open- | 1992 |
Results of intraoperative 5-fluorouracil supplementation on trabeculectomy for open-angle glaucoma.
Topics: Administration, Topical; Adult; Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; | 1992 |
Postoperative subconjunctival 5-fluorouracil injections and success probability of trabeculectomy in Japanese: results of 5-year follow-up.
Topics: Adult; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Injections; Intra | 1992 |
Combined no-stitch phacoemulsification cataract extraction with foldable silicone intraocular implant and holmium laser sclerostomy followed by 5-FU injections.
Topics: Aged; Cataract Extraction; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocular Press | 1992 |
5-fluorouracil in trabeculectomy for patients under the age of 40 years.
Topics: Adolescent; Adult; Age Factors; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle | 1992 |
Reversible corneal keratinization following trabeculectomy and treatment with 5-fluorouracil.
Topics: Aged; Conjunctiva; Corneal Diseases; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pressur | 1990 |
Initial 5-fluorouracil trabeculectomy in young patients.
Topics: Adolescent; Adult; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Fol | 1992 |
Trabeculectomy with 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Glaucoma, Angle | 1991 |
Reducing corneal toxicity of 5-fluorouracil in the early postoperative period following glaucoma filtering surgery.
Topics: Aged; Aged, 80 and over; Aphakia; Corneal Diseases; Female; Fluorouracil; Glaucoma, Open-Angle; Huma | 1991 |
Bandage contact lens augmentation of 5-fluorouracil treatment in glaucoma filtration surgery.
Topics: Aged; Cataract Extraction; Contact Lenses; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intra | 1991 |
Striate melanokeratosis following trabeculectomy with 5-fluorouracil.
Topics: Corneal Diseases; Fluorouracil; Glaucoma, Open-Angle; Humans; Keratosis; Male; Melanosis; Middle Age | 1990 |
Adjunctive use of delayed and adjustable low-dose 5-fluorouracil in refractory glaucoma.
Topics: Adolescent; Adult; Aged; Conjunctiva; Dose-Response Relationship, Drug; Drug Administration Schedule | 1990 |
Combined cataract implant and filtering surgery with 5-fluorouracil.
Topics: Aged; Cataract Extraction; Contrast Sensitivity; Female; Fluorouracil; Glaucoma, Angle-Closure; Glau | 1990 |
Long-term results of 5-fluorouracil trabeculectomy for primary open-angle glaucoma.
Topics: Adult; Aged; Epinephrine; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocula | 1989 |