fluorouracil has been researched along with Chronic Hepatitis C in 10 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 67-year-old male diagnosed as having inoperable advanced hepatocellular carcinoma with portal invasion was able to undergo resection after continuous intra-arterial chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP)." | 7.71 | [A case of advanced hepatocellular carcinoma with portal invasion resected after treatment by continuous intra-arterial chemotherapy with cisplatin and 5-fluorouracil]. ( Furutani, S; Hara, F; Ikeda, E; Kashiyama, Y; Matsumoto, H; Mitunaga, S; Moriyama, S; Naitoh, M; Nawa, S; Ohtuka, K; Tuji, T, 2001) |
| "While ribavirin mono-therapy regimens have minimal effect on patients with chronic hepatitis C virus (HCV) infections, they can be efficacious when combined with interferon." | 3.79 | Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs. ( Feigelstock, DA; Mihalik, KB, 2013) |
| "A 67-year-old male diagnosed as having inoperable advanced hepatocellular carcinoma with portal invasion was able to undergo resection after continuous intra-arterial chemotherapy with 5-fluorouracil (5-FU) and cisplatin (CDDP)." | 3.71 | [A case of advanced hepatocellular carcinoma with portal invasion resected after treatment by continuous intra-arterial chemotherapy with cisplatin and 5-fluorouracil]. ( Furutani, S; Hara, F; Ikeda, E; Kashiyama, Y; Matsumoto, H; Mitunaga, S; Moriyama, S; Naitoh, M; Nawa, S; Ohtuka, K; Tuji, T, 2001) |
| "A 62-year-old woman being treated for chronic hepatitis C and high blood pressure was shown by computed tomography to have tumors in the lateral and medial segments of her liver, and in her right breast." | 2.48 | [Liver arterial infusion chemotherapy with adjuvant trastuzumab for the simultaneous treatment of liver and breast cancer-a case report]. ( Akashi, M; Fujii, T; Inoue, Y; Momosaki, S; Nakayama, Y; Nishida, R; Saitsu, H; Shirouzu, K; Takahashi, H; Takahashi, R; Takami, Y; Takayoshi, K; Uchino, K, 2012) |
| "The relevant literature regarding treatment of liver cirrhosis complicated with HCC and synchronous colon Ca reveals poor and controversial outcomes." | 1.38 | How can we treat a patient with liver cirrhosis (hepatitis C virus), hepatocellular carcinoma, and synchronous colon cancer? ( Antoniou, E; Dimitroulis, D; Kostakis, A; Labadariou, A; Mantas, D; Nikitakis, N; Paraskeva, P; Smyrnis, A; Tsavaris, N; Vernicos, P, 2012) |
| "However, the immunological features of liver cirrhosis (LC) patients with advanced hepatocellular carcinoma (aHCC) treated by intra-arterial chemotherapy are still unclear." | 1.35 | Th1/Th2 balance: an important indicator of efficacy for intra-arterial chemotherapy. ( Higami, K; Ikehara, T; Kanayama, M; Matsui, T; Miki, K; Miyaki, D; Momiyama, K; Nagai, H; Sumino, Y; Watanabe, M, 2008) |
| "Diffused hepatoma was involved in the posterior lobe, and tumor thrombus extended into the main portal vein (Vp4)." | 1.33 | [A case report of hepatocellular carcinoma (Vp4)--an attempt to reduce residual tumor thrombus using combination therapy (hepatic arterial infusion, hepatic arterial embolization and radiation)]. ( Ebisui, C; Fujimoto, T; Fujiwara, S; Fukuchi, N; Hasuike, Y; Hayashi, N; Izumiyama, K; Kida, H; Koshino, T; Sakita, I; Tsujie, M; Yoshida, T, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mihalik, KB | 1 |
| Feigelstock, DA | 1 |
| Seo, JH | 1 |
| Song, MJ | 1 |
| Kanayama, M | 2 |
| Nagai, H | 3 |
| Sumino, Y | 3 |
| Momiyama, K | 2 |
| Antoniou, E | 1 |
| Mantas, D | 1 |
| Paraskeva, P | 1 |
| Dimitroulis, D | 1 |
| Smyrnis, A | 1 |
| Nikitakis, N | 1 |
| Labadariou, A | 1 |
| Tsavaris, N | 1 |
| Vernicos, P | 1 |
| Kostakis, A | 1 |
| Takahashi, R | 1 |
| Fujii, T | 1 |
| Inoue, Y | 1 |
| Takahashi, H | 1 |
| Akashi, M | 1 |
| Nishida, R | 1 |
| Takami, Y | 1 |
| Saitsu, H | 1 |
| Momosaki, S | 1 |
| Nakayama, Y | 1 |
| Uchino, K | 1 |
| Takayoshi, K | 1 |
| Shirouzu, K | 1 |
| Kida, H | 1 |
| Hasuike, Y | 1 |
| Fukuchi, N | 1 |
| Fujiwara, S | 1 |
| Hayashi, N | 1 |
| Tsujie, M | 1 |
| Yoshida, T | 1 |
| Ebisui, C | 1 |
| Sakita, I | 1 |
| Fujimoto, T | 1 |
| Koshino, T | 1 |
| Izumiyama, K | 1 |
| Fukumori, K | 1 |
| Yano, Y | 1 |
| Kuwaki, K | 1 |
| Sumie, S | 1 |
| Ando, E | 1 |
| Tanaka, M | 1 |
| Sata, M | 1 |
| Miyaki, D | 1 |
| Matsui, T | 1 |
| Higami, K | 1 |
| Ikehara, T | 1 |
| Watanabe, M | 1 |
| Miki, K | 1 |
| Matsumoto, H | 1 |
| Naitoh, M | 1 |
| Hara, F | 1 |
| Mitunaga, S | 1 |
| Ikeda, E | 1 |
| Moriyama, S | 1 |
| Tuji, T | 1 |
| Furutani, S | 1 |
| Nawa, S | 1 |
| Ohtuka, K | 1 |
| Kashiyama, Y | 1 |
1 review available for fluorouracil and Chronic Hepatitis C
| Article | Year |
|---|---|
[Liver arterial infusion chemotherapy with adjuvant trastuzumab for the simultaneous treatment of liver and breast cancer-a case report].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Ne | 2012 |
1 trial available for fluorouracil and Chronic Hepatitis C
| Article | Year |
|---|---|
Influence of the etiology of liver cirrhosis on the response to combined intra-arterial chemotherapy in patients with advanced hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocel | 2009 |
8 other studies available for fluorouracil and Chronic Hepatitis C
| Article | Year |
|---|---|
Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs.
Topics: Amino Acid Substitution; Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Fluorouracil | 2013 |
Education and Imaging. Hepatobiliary and Pancreatic: Complete remission after hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with decompensated cirrhosis.
Topics: Aged; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcino | 2016 |
Changes of host immunity in relation to efficacy in liver cirrhosis patients with advanced hepatocellular carcinoma treated by intra-arterial chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Case-Control Studie | 2009 |
How can we treat a patient with liver cirrhosis (hepatitis C virus), hepatocellular carcinoma, and synchronous colon cancer?
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Hepatocellular; Chemotherapy, Adj | 2012 |
[A case report of hepatocellular carcinoma (Vp4)--an attempt to reduce residual tumor thrombus using combination therapy (hepatic arterial infusion, hepatic arterial embolization and radiation)].
Topics: Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Embolization, Therapeutic; Fluorouracil; | 2005 |
[A case of chronic hepatitis C virus-related advanced hepatocelluar carcinoma surviving more than 8 years].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Administr | 2007 |
Th1/Th2 balance: an important indicator of efficacy for intra-arterial chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Drug Mon | 2008 |
[A case of advanced hepatocellular carcinoma with portal invasion resected after treatment by continuous intra-arterial chemotherapy with cisplatin and 5-fluorouracil].
Topics: Aged; Carcinoma, Hepatocellular; Cisplatin; Combined Modality Therapy; Fluorouracil; Hepatitis C, Ch | 2001 |