fluorouracil has been researched along with Chromosomes, Ring in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of an 84 years old prostate cancer patient with severe side effects after radiotherapy in 2006." | 1.39 | Persisting ring chromosomes detected by mFISH in lymphocytes of a cancer patient-a case report. ( Eble, MJ; Kriehuber, R; Pinkawa, M; Schmitz, S, 2013) |
| "The level of structural chromosomal aberrations two years after the therapeutic treatment was 0." | 1.28 | [Chromosomal restructurings and the distribution of chromosome fragile sites in the peripheral blood lymphocytes in a breast cancer patient after cytostatic therapy]. ( Iakovleva, TK; Moiseenko, VM; Monakhov, AS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmitz, S | 1 |
| Pinkawa, M | 1 |
| Eble, MJ | 1 |
| Kriehuber, R | 1 |
| Iakovleva, TK | 1 |
| Monakhov, AS | 1 |
| Moiseenko, VM | 1 |
2 other studies available for fluorouracil and Chromosomes, Ring
| Article | Year |
|---|---|
Persisting ring chromosomes detected by mFISH in lymphocytes of a cancer patient-a case report.
Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Chromosome Aberratio | 2013 |
[Chromosomal restructurings and the distribution of chromosome fragile sites in the peripheral blood lymphocytes in a breast cancer patient after cytostatic therapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltr | 1992 |