fluorouracil has been researched along with Choroid Neovascularization in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Macular relocation surgery involved phacoemulsification, vitrectomy, 360 degrees retinotomy, excision of choroidal neovascular membrane, and macular relocation using an infusion of 5-fluorouracil and low molecular weight heparin as adjuvant to prevent proliferative vitreoretinopathy." | 3.72 | Case selection in macular relocation surgery for age related macular degeneration. ( Briggs, M; Groenewald, C; Lancaster, E; Lenfestey, P; Li, KK; Lim, KS; Stanga, P; Wong, D, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wong, D | 1 |
| Stanga, P | 1 |
| Briggs, M | 1 |
| Lenfestey, P | 1 |
| Lancaster, E | 1 |
| Li, KK | 1 |
| Lim, KS | 1 |
| Groenewald, C | 1 |
| Kayikcioglu, OR | 1 |
| Falkenstein, I | 1 |
| Cheng, L | 1 |
| Kozak, I | 1 |
| La Bree, L | 1 |
| Azen, SP | 1 |
| Wong-Staal, F | 1 |
| Paoni, NF | 1 |
| Freeman, WR | 1 |
2 other studies available for fluorouracil and Choroid Neovascularization
| Article | Year |
|---|---|
Case selection in macular relocation surgery for age related macular degeneration.
Topics: Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Choroidal Neovascularization; Fluorouracil; Follow- | 2004 |
Therapy with ribozyme to the proliferating cell nuclear antigen-ribozyme and 5-fluorouracil of experimental choroidal neovascularization in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Choroidal Neovascularization; Combined Modality Therapy; D | 2006 |