fluorouracil has been researched along with Choroid Neoplasms in 8 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Choroid Neoplasms: Tumors of the choroid; most common intraocular tumors are malignant melanomas of the choroid. These usually occur after puberty and increase in incidence with advancing age. Most malignant melanomas of the uveal tract develop from benign melanomas (nevi).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 59-year-old patient with a coexisting primary choroidal melanoma and colorectal cancer was treated with external beam radiation (EBR) of his choroidal melanoma and systemic chemotherapy with leukovorin/5 fluorouracil (FU) for treatment of his metastatic colorectal cancer." | 3.74 | Regression of radiation-induced macular edema after systemic bevacizumab. ( Bakri, SJ; Pulido, JS; Solano, JM, 2007) |
| "A case of relapsing breast carcinoma presenting with acute visual loss secondary to choroidal metastases is described." | 1.28 | Choroidal metastases as a presenting sign after 24 years of a primary breast cancer. ( Baheti, D; Consul, S; Gupta, R, 1991) |
| "A choroidal metastasis from a primary breast carcinoma in a 32-year-old woman underwent clinically complete regression during a course of five-drug combined chemotherapy for widespread metastases." | 1.26 | Response of a choroidal metastasis to multiple-drug chemotherapy. ( Brinkley, JR, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez-Alvarez, MJ | 1 |
| Arriola-Villalobos, P | 1 |
| Reche-Frutos, J | 1 |
| García-Sánchez, J | 1 |
| Samuel, J | 1 |
| Flood, TP | 1 |
| Agbemadzo, B | 1 |
| Renta, V | 1 |
| Mullai, N | 1 |
| Osafo, DC | 1 |
| Holloway, N | 1 |
| Cohen, JA | 1 |
| Asproudis, I | 1 |
| Gorezis, S | 1 |
| Stefaniotou, M | 1 |
| Peschos, D | 1 |
| Psilas, K | 1 |
| Solano, JM | 1 |
| Bakri, SJ | 1 |
| Pulido, JS | 1 |
| Brinkley, JR | 1 |
| Caroli-Bosc, FX | 1 |
| Caujolle, C | 1 |
| Gastaud, P | 1 |
| Montoya, ML | 1 |
| Demarquay, JF | 1 |
| Delmont, JP | 1 |
| Biswal, BM | 1 |
| Gupta, R | 1 |
| Consul, S | 1 |
| Baheti, D | 1 |
8 other studies available for fluorouracil and Choroid Neoplasms
| Article | Year |
|---|---|
[Choroidal metastasis from a breast carcinoma. Diagnosis and follow-up with optical coherence tomography and fluorescein angiography and autofluorescence with HRA-II (Heidelberg Retina Angiograph)].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; C | 2009 |
Choroidal metastasis from adenocarcinoma of the esophagus.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Choroid Neoplasms | 2003 |
Choroidal metastasis from breast carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Ductal, B | 2006 |
Regression of radiation-induced macular edema after systemic bevacizumab.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetab | 2007 |
Response of a choroidal metastasis to multiple-drug chemotherapy.
Topics: Adult; Antineoplastic Agents; Breast Neoplasms; Choroid Neoplasms; Cyclophosphamide; Drug Therapy, C | 1980 |
[Probable choroid metastasis of an esophageal adenocarcinoma that regressed with chemotherapy].
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Choroid Neoplasms; Cisplatin; | 1998 |
Restoration of vision following combination chemotherapy of nasopharyngeal carcinoma choroidal metastases.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Choroid Neoplasms; | 2001 |
Choroidal metastases as a presenting sign after 24 years of a primary breast cancer.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Choroid Neoplasms; | 1991 |