Page last updated: 2024-10-27

fluorouracil and Choroid Hemorrhage

fluorouracil has been researched along with Choroid Hemorrhage in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Choroid Hemorrhage: Hemorrhage from the vessels of the choroid.

Research Excerpts

ExcerptRelevanceReference
"The risk of suprachoroidal hemorrhage was strongly associated with the level of the preoperative intraocular pressure."2.67Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group. ( , 1992)
"Complications included suprachoroidal hemorrhage in 7 (14%) of 49 eyes and intraoperative vitreous hemorrhage in 2."1.29Holmium laser sclerectomy. Success and complications. ( Bellows, AR; Hutchinson, BT; Lytle, R; Puliafito, CA; Schuman, JS; Stinson, WG, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schuman, JS1
Stinson, WG1
Hutchinson, BT1
Bellows, AR1
Puliafito, CA1
Lytle, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000122]Phase 30 participants Interventional1985-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fluorouracil and Choroid Hemorrhage

ArticleYear
Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group.
    American journal of ophthalmology, 1992, May-15, Volume: 113, Issue:5

    Topics: Aged; Cataract Extraction; Choroid Hemorrhage; Fluorouracil; Glaucoma; Humans; Incidence; Intraocula

1992

Other Studies

1 other study available for fluorouracil and Choroid Hemorrhage

ArticleYear
Holmium laser sclerectomy. Success and complications.
    Ophthalmology, 1993, Volume: 100, Issue:7

    Topics: Aged; Choroid Hemorrhage; Chronic Disease; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao

1993