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fluorouracil and Cholestasis, Intrahepatic

fluorouracil has been researched along with Cholestasis, Intrahepatic in 4 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gerhardt, T1
Rings, D1
Höblinger, A1
Heller, J1
Sauerbruch, T1
Schepke, M1
Knox, JJ1
Hedley, D1
Oza, A1
Feld, R1
Siu, LL1
Chen, E1
Nematollahi, M1
Pond, GR1
Zhang, J1
Moore, MJ1
Brooks, AJ1
Begg, EJ1
Chapman, BA1
Fitzharris, BM1
Foitl, DR1
Hyman, G1
Lefkowitch, JH1

Trials

1 trial available for fluorouracil and Cholestasis, Intrahepatic

ArticleYear
Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Apr-01, Volume: 23, Issue:10

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemot

2005

Other Studies

3 other studies available for fluorouracil and Cholestasis, Intrahepatic

ArticleYear
Combination of bilateral metal stenting and trans-stent photodynamic therapy for palliative treatment of hilar cholangiocarcinoma.
    Zeitschrift fur Gastroenterologie, 2010, Volume: 48, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Bile D

2010
Two cases of severe liver injury possibly related to 5-fluorouracil and calcium folinate.
    Internal medicine journal, 2007, Volume: 37, Issue:5

    Topics: Acute Disease; Aged; Antineoplastic Agents; Cholestasis, Intrahepatic; Colorectal Neoplasms; Fluorou

2007
Jaundice and intrahepatic cholestasis following high-dose megestrol acetate for breast cancer.
    Cancer, 1989, Feb-01, Volume: 63, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Breast Neoplasms; Cholestasis, Intr

1989