fluorouracil has been researched along with Cholangitis in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Cholangitis: Inflammation of the biliary ductal system (BILE DUCTS); intrahepatic, extrahepatic, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the number of long-term esophageal cancer survivors has been increasing due to advances in early detection and therapy." | 1.40 | Second primary pancreatic adenocarcinoma three years after successfully treated index esophageal cancer. ( Dasanu, CA; Nandy, N, 2014) |
| "Results of liver transplantation in the treatment of cholangiocarcinoma have been poor as a result of the high incidence of locoregional dissemination and tumor recurrence." | 1.31 | Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma. ( Chinnakotla, S; DeRoover, A; Fox, I; Langnas, A; McCashland, T; Shaw, B; Sorrell, M; Sudan, D; Tempero, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nandy, N | 1 |
| Dasanu, CA | 1 |
| Hecht, JR | 1 |
| Farrell, JJ | 1 |
| Senzer, N | 1 |
| Nemunaitis, J | 1 |
| Rosemurgy, A | 1 |
| Chung, T | 1 |
| Hanna, N | 1 |
| Chang, KJ | 1 |
| Javle, M | 1 |
| Posner, M | 1 |
| Waxman, I | 1 |
| Reid, A | 1 |
| Erickson, R | 1 |
| Canto, M | 1 |
| Chak, A | 1 |
| Blatner, G | 1 |
| Kovacevic, M | 1 |
| Thornton, M | 1 |
| Sudan, D | 1 |
| DeRoover, A | 1 |
| Chinnakotla, S | 1 |
| Fox, I | 1 |
| Shaw, B | 1 |
| McCashland, T | 1 |
| Sorrell, M | 1 |
| Tempero, M | 1 |
| Langnas, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Registry Study of Neoadjuvant Therapy in Conjunction With Liver Transplantation for Cholangiocarcinoma[NCT00301379] | 59 participants (Actual) | Observational | 2005-08-12 | Terminated (stopped due to Low accrual) | |||
| A Single-Arm Nonrandomized Phase II Study of Liver Transplantation in Locally Advanced Unresectable Non-Metastatic Intrahepatic Cholangiocarcinoma Treated With Neoadjuvant Systemic Therapy[NCT06140134] | 30 participants (Anticipated) | Observational [Patient Registry] | 2023-12-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fluorouracil and Cholangitis
| Article | Year |
|---|---|
EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study.
Topics: Adenoviruses, Human; Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma; Chemoradiotherapy; Cho | 2012 |
2 other studies available for fluorouracil and Cholangitis
| Article | Year |
|---|---|
Second primary pancreatic adenocarcinoma three years after successfully treated index esophageal cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Ad | 2014 |
Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma.
Topics: Adult; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarc | 2002 |
Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma.
Topics: Adult; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarc | 2002 |
Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma.
Topics: Adult; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarc | 2002 |
Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma.
Topics: Adult; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarc | 2002 |